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anti-Ras Homolog Gene Family, Member J (RHOJ) Antibodies

RHOJ encodes one of the many small GTP-binding proteins in the Rho family shown to be associated with focal adhesions in endothelial cells (PMID: 21148427, 22103495). Additionally we are shipping Ras Homolog Gene Family, Member J Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RHOJ 57381 Q9H4E5
Anti-Rat RHOJ RHOJ 299145  
Anti-Mouse RHOJ RHOJ 80837 Q9ER71
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Top anti-Ras Homolog Gene Family, Member J Antibodies at antibodies-online.com

Showing 10 out of 53 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to RHOJ on HeLa cell (antibody concentration 60 µg/mL). RHOJ monoclonal antibody (M01), clone 1E4 Western Blot analysis of RHOJ expression in HepG2. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin fixed, paraffin embedded Mouse heart tissue stained with RhoJ Antibody  followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RHOJ Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis of RhoJ Antibody  in HepG2,MDA-MB231 cell line lysates (35ug/lane).This demonstrates the RHOJ antibody detected the RHOJ protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-RHOJ Antibody Titration: 0.2-1 ug/mlPositive Control: 721_B cell lysate WB Suggested Anti-RHOJ  Antibody Titration: 0.2-1 µg/mL  Positive Control:.21_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB RHOJ Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RHOJ Antibody (Center) for immunohistochemistry.  Clinical relevance has not been evaluated. RHOJ Antibody (Center)  western blot analysis in HepG2,MDA-MB231 cell line lysates (35ug/lane).This demonstrates the RHOJ antibody detected the RHOJ protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IF, ELISA, WB RHOJ monoclonal antibody (M01), clone 1E4 Western Blot analysis of RHOJ expression in HepG2 Immunofluorescence of monoclonal antibody to RHOJ on HeLa cell. [antibody concentration 60 ug/ml] 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated IF, IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB RHOJ antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Mouse Un-conjugated IF, IHC (p), WB   50 μL Log in to see 8 to 10 Days
$451.00
Details

RHOJ Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Top referenced anti-Ras Homolog Gene Family, Member J Antibodies

  1. Human Monoclonal RHOJ Primary Antibody for IF, WB - ABIN394530 : Rose, Behm, Drgon, Johnson, Uhl: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. in Molecular medicine (Cambridge, Mass.) 2010 (PubMed)
    Show all 5 references for ABIN394530

  2. Human Polyclonal RHOJ Primary Antibody for EIA, IHC (p) - ABIN954544 : Nishikimi, Meller, Uekawa, Isobe, Schwartz, Maruyama: Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes. in FEBS letters 2005 (PubMed)
    Show all 4 references for ABIN954544

  3. Human Monoclonal RHOJ Primary Antibody for IF, ELISA - ABIN566105 : Fukushima, Okada, Kataoka, Hirashima, Yoshida, Mann, Gomi, Nishida, Nishikawa, Uemura: Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice. in The Journal of clinical investigation 2011 (PubMed)
    Show all 2 references for ABIN566105

More Antibodies against Ras Homolog Gene Family, Member J Interaction Partners

Human Ras Homolog Gene Family, Member J (RHOJ) interaction partners

  1. FMNL3 interacts with Cdc42 and RhoJ, two Rho family GTPases known to be required for lumen formation. FMNL3 and RhoJ are concentrated at the early apical surface, or AMIS, and regulate the formation of radiating actin cables from this site.

  2. RhoJ-knockout mice showed reduced tumour growth and diminished tumour vessel density, identifying a role for RhoJ in mediating tumour angiogenesis. Studies give insight into the molecular function of RhoJ in regulating cell motility.

  3. These results identify RhoJ blockade as a selective and effective therapeutic strategy for targeting tumor vasculature with minimal side effects.

  4. These observations identify RHOJ as a melanoma linchpin determinant that regulates both actin cytoskeletal dynamics and chemoresistance by activating PAK1 (show PAK1 Antibodies).

  5. Arhgef15 acts as an endothelial cell-specific GEF to mediate VEGF-induced Cdc42 activation and potentiate RhoJ inactivation, thereby promoting actin polymerization and cell motility.

  6. we identified RhoJ and its effector PAK1 (show PAK1 Antibodies), as key modulators of melanoma cell sensitivity to DNA damage

  7. Our study supports a novel role for the Rho family member RhoJ in ednothelial cell morphogenesis and in particular in lumen formation

  8. RhoJ is endothelial-expressed in vivo, activated by vascular endothelial growth factor, localizes to focal adhesions, regulates endothelial cell migration and tube formation, and modulates actomyosin contractility and focal adhesion numbers.

  9. TCL is essential for clathrin-dependent endocytosed receptors to enter the early/sorting endosomes

Mouse (Murine) Ras Homolog Gene Family, Member J (RHOJ) interaction partners

  1. RhoJ-knockout mice showed reduced tumour growth and diminished tumour vessel density, identifying a role for RhoJ in mediating tumour angiogenesis. Studies give insight into the molecular function of RhoJ in regulating cell motility.

  2. These results identify RhoJ blockade as a selective and effective therapeutic strategy for targeting tumor vasculature with minimal side effects.

  3. RhoJ is endothelial-expressed in vivo, activated by vascular endothelial growth factor, localizes to focal adhesions, regulates endothelial cell migration and tube formation, and modulates actomyosin contractility and focal adhesion numbers.

  4. The results strongly suggest that TCL/TC10betaL regulates adipocyte differentiation by controlling mitotic clonal expansion and this regulatory effect is closely linked to C/EBPbeta (show CEBPB Antibodies) and C/EBPdelta (show CEBPD Antibodies) expression.

  5. TCL/TC10betaL has a crucial role in the early stage of adipocyte differentiation, is probably linked to the PPARgamma (show PPARG Antibodies) pathway, and up-regulates epression of genes associated with adipogenesis.

  6. Insulin (show INS Antibodies) induces phosphatidylinositol 3-phosphate formation through TC10 (show RHOQ Antibodies) activation.

Ras Homolog Gene Family, Member J (RHOJ) Antigen Profile

Protein Summary

This gene encodes one of the many small GTP-binding proteins in the Rho family shown to be associated with focal adhesions in endothelial cells (PMID: 21148427, 22103495). The encoded protein is activated by vascular endothelial growth factor and may regulate angiogenesis.

Gene names and symbols associated with RHOJ

  • ras homolog gene family, member J (RHOJ) antibody
  • ras homolog gene family, member J (rhoj) antibody
  • ras homolog family member J (RHOJ) antibody
  • ras homolog family member J (rhoj) antibody
  • ras homolog gene family, member J (LOC100350942) antibody
  • ras homolog family member J (Rhoj) antibody
  • ras homolog gene family, member J (Rhoj) antibody
  • 1110005O19Rik antibody
  • Arhj antibody
  • AW210585 antibody
  • MGC83410 antibody
  • RASL7B antibody
  • RHOJ antibody
  • si:dkey-100h21.1 antibody
  • TC10B antibody
  • TC10L antibody
  • TCL antibody

Protein level used designations for RHOJ

ras homolog gene family, member J , TC10-like Rho GTPase , rho-related GTP-binding protein RhoJ , RAS-like, family 7, member B , ras-like protein family member 7B , tc10-like GTP-binding protein , tc10-like GTP-binding protein TCL

GENE ID SPECIES
423513 Gallus gallus
444554 Xenopus laevis
452960 Pan troglodytes
540619 Bos taurus
556371 Danio rerio
612985 Canis lupus familiaris
705603 Macaca mulatta
100125013 Xenopus (Silurana) tropicalis
100155474 Sus scrofa
100350942 Oryctolagus cuniculus
57381 Homo sapiens
299145 Rattus norvegicus
80837 Mus musculus
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