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Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Additionally we are shipping RIN1 Antibodies (40) and many more products for this protein.
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Findings suggest that RIN1 orchestrates RAB5 (show RAB5A Proteins) activation, ABL kinase activation and BIN1 (show BIN1 Proteins) recruitment to determine EGFR (show EGFR Proteins) fate.
over-expression of RIN1 may play an important role in the progression of non-small cell lung cancer and RIN1 expression may offer a valuable marker for predicting the outcome of patients with NSCLC
RIN1 plays an important role in gastric adenocarcinoma progression and that a high RIN1 expression predicts an unfavorable prognosis in gastric adenocarcinoma patients.
RIN1 expression could be a potential prognostic predictor for the melanoma patients and provide a potential target therapy for melanoma treatment.
RIN1 expression could be a potential prognostic predictor for bladder urothelial carcinoma (UC) patients.
These data identify a novel PKD signaling pathway through RIN1 and Abl kinases that is involved in the regulation of actin remodeling and cell migration.
BCR (show BCR Proteins)-ABL1 (show ABL1 Proteins) kinase activity is regulated by RIN1
Plays an important role in both insulin receptor (show INSR Proteins) membrane trafficking and signaling.
These results indicate that the RIN1 gene serves as an important signal transduction system for evaluating the malignancy of colorectal cancer.
Rin1 regulates EGFR (show EGFR Proteins) degradation in cooperation with STAM (show STAM Proteins)
These results provide insight into regulated expression of Rin1, define a promoter useful in telencephalic neuron studies, and describe a novel REST site variant directing expression to mature neurons.
This study provided evidence that Rin1 normally functions as a negative regulator of fear learning and memory (Rin1-/- mice have enhanced fear conditioning and diminished fear extinction).
Rin1 links histone ubiquitylation to gene silencing and X inactivation.
RIN1 is an ABL tyrosine kinase activator and a regulator of epithelial-cell adhesion and migration.
the EphA4 (show EPHA4 Proteins) receptor is required for synaptic plasticity in the amygdala, raising the possibility that an underlying mechanism of Rin1 function in amygdala is to down-regulate EphA4 (show EPHA4 Proteins) signaling by promoting its endocytosis.
Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.
Ras and Rab interactor 1
, ras and Rab interactor 1-like
, ras and Rab interactor 1
, ras inhibitor 1
, ras inhibitor JC99
, ras inhibitor RIN1
, ras interaction/interference protein 1
, ras inhibitor