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Ras and Rab Interactor 1 Proteins (RIN1)

Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Additionally we are shipping RIN1 Antibodies (41) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RIN1 9610 Q13671
RIN1 225870 Q921Q7
RIN1 207119 P97680
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Top RIN1 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$4,269.83
Details

RIN1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Ras and Rab Interactor 1 (RIN1) Interaction Partners

Human Ras and Rab Interactor 1 (RIN1) interaction partners

  1. Findings suggest that RIN1 orchestrates RAB5 (show RAB5A Proteins) activation, ABL kinase activation and BIN1 (show BIN1 Proteins) recruitment to determine EGFR (show EGFR Proteins) fate.

  2. over-expression of RIN1 may play an important role in the progression of non-small cell lung cancer and RIN1 expression may offer a valuable marker for predicting the outcome of patients with NSCLC

  3. RIN1 plays an important role in gastric adenocarcinoma progression and that a high RIN1 expression predicts an unfavorable prognosis in gastric adenocarcinoma patients.

  4. RIN1 expression could be a potential prognostic predictor for the melanoma patients and provide a potential target therapy for melanoma treatment.

  5. RIN1 expression could be a potential prognostic predictor for bladder urothelial carcinoma (UC) patients.

  6. These data identify a novel PKD signaling pathway through RIN1 and Abl kinases that is involved in the regulation of actin remodeling and cell migration.

  7. BCR (show BCR Proteins)-ABL1 (show ABL1 Proteins) kinase activity is regulated by RIN1

  8. Plays an important role in both insulin receptor (show INSR Proteins) membrane trafficking and signaling.

  9. These results indicate that the RIN1 gene serves as an important signal transduction system for evaluating the malignancy of colorectal cancer.

  10. Rin1 regulates EGFR (show EGFR Proteins) degradation in cooperation with STAM (show STAM Proteins)

Mouse (Murine) Ras and Rab Interactor 1 (RIN1) interaction partners

  1. BCR (show BCR Proteins)-ABL1 (show ABL1 Proteins) kinase activity is regulated by RIN1

  2. These results provide insight into regulated expression of Rin1, define a promoter useful in telencephalic neuron studies, and describe a novel REST site variant directing expression to mature neurons.

  3. This study provided evidence that Rin1 normally functions as a negative regulator of fear learning and memory (Rin1-/- mice have enhanced fear conditioning and diminished fear extinction).

  4. Rin1 links histone ubiquitylation to gene silencing and X inactivation.

  5. RIN1 is an ABL tyrosine kinase activator and a regulator of epithelial-cell adhesion and migration.

  6. the EphA4 (show EPHA4 Proteins) receptor is required for synaptic plasticity in the amygdala, raising the possibility that an underlying mechanism of Rin1 function in amygdala is to down-regulate EphA4 (show EPHA4 Proteins) signaling by promoting its endocytosis.

RIN1 Protein Profile

Protein Summary

Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.

Gene names and symbols associated with RIN1

  • Ras and Rab interactor 1 (RIN1)
  • Ras and Rab interactor 1 (Rin1)
  • RIN1 protein

Protein level used designations for RIN1

Ras and Rab interactor 1 , ras and Rab interactor 1-like , ras and Rab interactor 1 , ras inhibitor 1 , ras inhibitor JC99 , ras inhibitor RIN1 , ras interaction/interference protein 1 , ras inhibitor

GENE ID SPECIES
611928 Canis lupus familiaris
714321 Macaca mulatta
100058267 Equus caballus
100395614 Callithrix jacchus
100437658 Pongo abelii
100482238 Ailuropoda melanoleuca
9610 Homo sapiens
225870 Mus musculus
207119 Rattus norvegicus
100520715 Sus scrofa
509295 Bos taurus
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