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Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Additionally we are shipping RIN1 Proteins (5) and many more products for this protein.
Showing 10 out of 45 products:
Human Polyclonal RIN1 Primary Antibody for IHC, IHC (p) - ABIN4350556
Balaji, French, Miller, Colicelli: The RAB5-GEF function of RIN1 regulates multiple steps during Listeria monocytogenes infection. in Traffic (Copenhagen, Denmark) 2014
Findings suggest that RIN1 plays an important oncogenic role in clear cell renal cell carcinoma (show MOK Antibodies) malignancy by activation of EGFR (show EGFR Antibodies) signaling through interacting with Rab25 (show RAB25 Antibodies).
Smad2 (show SMAD2 Antibodies) is a key scaffold, allowing RIN1 to act as a GTP (show AK3 Antibodies) exchange factor for MFN2 (show MFN2 Antibodies)-GTPase (show RACGAP1 Antibodies) activation to promote mitochondrial ATP synthesis and suppress superoxide production during mitochondrial fusion.
Overexpression experiments in tandem with pull-down assays indicated that specific Ser291/292 phosphorylation of RIN1 favored binding to activated Ras
analysis of a novel deregulated mechanism in chronic myeloid leukemia (show BCL11A Antibodies) patients, indicating BIN1 (show BIN1 Antibodies) and RIN1 as players in the maintenance of the abnormal RTK signaling in this hematological disease
Findings suggest that RIN1 orchestrates RAB5 (show RAB5A Antibodies) activation, ABL kinase activation and BIN1 (show BIN1 Antibodies) recruitment to determine EGFR (show EGFR Antibodies) fate.
over-expression of RIN1 may play an important role in the progression of non-small cell lung cancer and RIN1 expression may offer a valuable marker for predicting the outcome of patients with NSCLC
RIN1 plays an important role in gastric adenocarcinoma progression and that a high RIN1 expression predicts an unfavorable prognosis in gastric adenocarcinoma patients.
RIN1 expression could be a potential prognostic predictor for the melanoma patients and provide a potential target therapy for melanoma treatment.
RIN1 expression could be a potential prognostic predictor for bladder urothelial carcinoma (UC) patients.
These data identify a novel PKD signaling pathway through RIN1 and Abl kinases that is involved in the regulation of actin remodeling and cell migration.
BCR (show BCR Antibodies)-ABL1 (show ABL1 Antibodies) kinase activity is regulated by RIN1
These results provide insight into regulated expression of Rin1, define a promoter useful in telencephalic neuron studies, and describe a novel REST site variant directing expression to mature neurons.
This study provided evidence that Rin1 normally functions as a negative regulator of fear learning and memory (Rin1-/- mice have enhanced fear conditioning and diminished fear extinction).
Rin1 links histone ubiquitylation to gene silencing and X inactivation.
RIN1 is an ABL tyrosine kinase activator and a regulator of epithelial-cell adhesion and migration.
the EphA4 (show EPHA4 Antibodies) receptor is required for synaptic plasticity in the amygdala, raising the possibility that an underlying mechanism of Rin1 function in amygdala is to down-regulate EphA4 (show EPHA4 Antibodies) signaling by promoting its endocytosis.
Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.
Ras and Rab interactor 1
, ras and Rab interactor 1-like
, ras and Rab interactor 1
, ras inhibitor 1
, ras inhibitor JC99
, ras inhibitor RIN1
, ras interaction/interference protein 1
, ras inhibitor