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Ras and Rab Interactor 2 Proteins (RIN2)

The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. Additionally we are shipping RIN2 Antibodies (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat RIN2 RIN2 311494  
RIN2 54453 Q8WYP3
RIN2 74030 Q9D684
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Top RIN2 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

RIN2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Ras and Rab Interactor 2 (RIN2) Interaction Partners

Human Ras and Rab Interactor 2 (RIN2) interaction partners

  1. We describe the fourth family with RIN2 syndrome in two siblings with a novel homozygous mutation in the RIN2 gene and exhibiting additional clinical features that may also contribute to further delineation of the phenotypic spectrum.

  2. These findings confirm that RIN2 defects are associated with a distinct genodermatosis and underscore the involvement of RIN2 and its associated pathways in the pathogenesis of connective tissue disorders.

  3. RIN2 deficiency results in macrocephaly, alopecia, cutis laxa, and scoliosis: MACS syndrome.

RIN2 Protein Profile

Protein Summary

The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with RIN2

  • Ras and Rab interactor 2 (Rin2)
  • Ras and Rab interactor 2 (RIN2)
  • Ras and Rab interactor 2 (rin2)
  • 2010003K16Rik protein
  • 4632403N06Rik protein
  • AW821980 protein
  • MACS protein
  • RASSF4 protein
  • RIN2 protein
  • RINL protein

Protein level used designations for RIN2

ras and Rab interactor 2 , Ras and Rab interactor 2 , RAB5 interacting protein 2 , ras and Rab interactor 2-like , RAS association (RalGDS/AF-6) domain containing protein JC265 , RAS association domain family 4 , RAS inhibitor JC265 , RAS interaction/interference protein 2 , ras interaction/interference protein 2

GENE ID SPECIES
311494 Rattus norvegicus
421246 Gallus gallus
458123 Pan troglodytes
477139 Canis lupus familiaris
537459 Bos taurus
702775 Macaca mulatta
100033251 Monodelphis domestica
100144744 Xenopus (Silurana) tropicalis
100386384 Callithrix jacchus
100461092 Pongo abelii
100543757 Meleagris gallopavo
100552389 Anolis carolinensis
54453 Homo sapiens
74030 Mus musculus
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