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anti-Ras-Related Associated with Diabetes (RRAD) Antibodies

human homolog is a GTP-binding protein. Additionally we are shipping and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RRAD 6236 P55042
RRAD 56437  
RRAD 83521  
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Top anti-RRAD Antibodies at antibodies-online.com

Showing 10 out of 37 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-RRAD Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-RRAD Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from HeLa/HepG2/MCF-7 cells, using RAD Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human heart tissue, using RAD Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details
Cow Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Mouse Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IC, IF, IP, IHC, WB Immunofluorescent analysis of RRAD staining in HepG2 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of RRAD staining in human muscle formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details

RRAD Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
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Mouse (Murine) , ,
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Rat (Rattus) , ,
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Top referenced anti-RRAD Antibodies

  1. Human Polyclonal RRAD Primary Antibody for WB - ABIN2786776 : Chang, Zhang, Tseng, Xie, Ilany, Brüning, Sun, Zhu, Cui, Youker, Yang, Day, Kahn, Chen: Rad GTPase deficiency leads to cardiac hypertrophy. in Circulation 2007 (PubMed)

  2. Human Polyclonal RRAD Primary Antibody for IF, IHC - ABIN1534965 : Reynet, Kahn: Rad: a member of the Ras family overexpressed in muscle of type II diabetic humans. in Science (New York, N.Y.) 1993 (PubMed)

More Antibodies against RRAD Interaction Partners

Human Ras-Related Associated with Diabetes (RRAD) interaction partners

  1. Data show that Ras-related associated with diabetes protein (RRAD) directly binds to the p65 (show GORASP1 Antibodies) subunit of the NF-kappa B (NF-kappaB (show NFKB1 Antibodies))complex and inhibits the nuclear translocation of p65 (show GORASP1 Antibodies), which in turn negatively regulates the NF-kappaB (show NFKB1 Antibodies) signaling

  2. Brg1 (show SMARCA4 Antibodies) inhibits proliferation and migration of human aortic smooth muscle cells by directly up-regulating RRAD in aortic dissection.

  3. RRAD promotes EGFR (show EGFR Antibodies)-mediated STAT3 (show STAT3 Antibodies) activation and induces temozolomide resistance of malignant glioblastoma.

  4. RRAD expression is frequently decreased in lung cancer. Ectopic expression of RRAD greatly reduces glycolysis whereas knockdown of RRAD promotes glycolysis in lung cancer cells.

  5. Rad suppresses the NF-Kappa-B (show NFKB1 Antibodies) mediated transcription and downstream gene activation. Rad can directly bind to RelA/p65 (show NFkBP65 Antibodies) and suppress the interaction of RelA/p65 (show NFkBP65 Antibodies) with the NF-kappa-B (show NFKB1 Antibodies) response DNA element.

  6. Ras(V12)-mediated oncogenic transformation induces RRAD epigenetic inactivation, which in turn promotes glucose uptake and may contribute to ovarian cancer

  7. RRAD hypermethylation is associated with esophageal squamous cell carcinoma.

  8. Mouse Rad Q65P (the murine equivalent of human Rad Q66P) inhibits L-type currents conducted by CaV1.2 (show CACNA1C Antibodies) or CaV1.3 (show CACNA1D Antibodies) channels as potently as wild-type Rad (>95% inhibition of both channels).

  9. Rad over expression could be a molecular target to improve bortezomib sensitivity in human leukemia and lymphoma.

  10. results indicate that RRAD might act as a functional tumor suppressor and its epigenetic inactivation may play an important role in NPC (show NPC1 Antibodies) development

Mouse (Murine) Ras-Related Associated with Diabetes (RRAD) interaction partners

  1. The Rad(-/-) phenotype is marked by enhanced systolic and diastolic function, which is consistent with a model that does not progress into heart failure.

  2. Rad, Gem (show GEM Antibodies) and Rem (show REM1 Antibodies) all reduce depolarization-dependent Ca2 (show CA2 Antibodies)+ entry in developing myotubes.

  3. A dominant-negative Rad mutation causes arrhythmogenesis via PKA-mediated phosphorylation of RYR2 (show RYR2 Antibodies) activity in the heart.

  4. Depletion of Rad GTPase (show RACGAP1 Antibodies) increases L-type calcium channel current leading to increased cardiac contraction, without stimulating cardiac hypertrophy.

  5. Mouse Rad Q65P (the murine equivalent of human Rad Q66P) inhibits L-type currents conducted by CaV1.2 (show CACNA1C Antibodies) or CaV1.3 (show CACNA1D Antibodies) channels as potently as wild-type Rad (>95% inhibition of both channels).

  6. Rad GTPase (show RACGAP1 Antibodies) inhibits cardiac fibrosis through connective tissue growth factor (show CTGF Antibodies) in failing hearts.

  7. both Rem (show REM1 Antibodies) and Rad bind directly to Ca2 (show CA2 Antibodies)+ channel beta-subunits (CaV (show CA5A Antibodies) beta) in vivo

  8. These results demonstrate a potential synergistic interaction between increased expression of Rad and high-fat diet in creation of insulin (show INS Antibodies) resistance and altered lipid metabolism present in type 2 diabetes.

  9. Nuclear localization of RGK proteins (Rad, Rem (show REM1 Antibodies), and Rem2 (show REM2 Antibodies)) contributes to the suppression of RGK-mediated cell shape remodeling.

  10. Rad is a novel mediator that inhibits cardiac hypertrophy through the CaMKII (show CAMK2G Antibodies) pathway

RRAD Antigen Profile

Protein Summary

human homolog is a GTP-binding protein

Gene names and symbols associated with RRAD

  • Ras-related associated with diabetes (RRAD) antibody
  • Ras-related associated with diabetes (Rrad) antibody
  • Rad antibody
  • RAD1 antibody
  • REM3 antibody
  • RRAD antibody
  • ZGC:63471 antibody

Protein level used designations for RRAD

Ras-related associated with diabetes , GTP-binding protein RAD , RAS (RAD and GEM) like GTP binding 3 , ras associated with diabetes , Ras-like GTP-binding protein rad , RAD1

GENE ID SPECIES
415790 Gallus gallus
695086 Macaca mulatta
741038 Pan troglodytes
6236 Homo sapiens
56437 Mus musculus
83521 Rattus norvegicus
611304 Canis lupus familiaris
505165 Bos taurus
Selected quality suppliers for anti-RRAD (RRAD) Antibodies
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