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binds GTP; member of the subfamily of Ras-homologous GTP binding proteins. Additionally we are shipping Ras-Related GTP Binding A Antibodies (43) and Ras-Related GTP Binding A Proteins (10) and many more products for this protein.
The data indicate that the RRAGA mutations, associated with autosomal dominant cataracts, play a role in the disease by acting through disruption of mTORC1 signaling.
Data suggest that both microtubule-associated DYNLT (dynein light chain Tctex-type 1 (show DYNLT1 ELISA Kits)) and cytoplasmic DYNLT (dynein 1 intermediate chain 2 DYNC1LI2 (show DYNC1LI2 ELISA Kits)) are equally able to bind to small GTPases Rab3D (Rab3d (show RAB3D ELISA Kits) GTPase (show RACGAP1 ELISA Kits)) and RagA (Ras-related GTP binding A).
Data suugest that S-phase kinase-associated protein 2 (Skp2)-mediated Ras-related GTP-binding protein RagA ubiquitination recruits GATOR1 to restrict mTORC1 signaling upon sustained amino acid stimulation.
A mechanism for regulation of mTORC1 signaling by RNF152 (show RNF152 ELISA Kits)-mediated K63-linked polyubiquitination of RagA.
RagA and RagB (show RRAGB ELISA Kits) are key regulators of lysosomal function and cardiac protection.
RagA deficiency leads to E10.5 embryonic death, loss of mTORC1 activity, and severe growth defects.
Fip1 expression and the Fip1-dependent mRNA alternative polyadenylation program change during embryonic stem cell differentiation and are restored to an embryonic stem cell-like state during somatic reprogramming.
Overexpression of constitutively active (ca)RagA and caRagC increased mTORC1 activity, as determined by increased S6K1 (show RPS6KB1 ELISA Kits) phosphorylation.
binds GTP\; member of the subfamily of Ras-homologous GTP binding proteins
, ras-related GTP-binding protein A
, adenovirus E3 14.7 kDa-interacting protein 1
, adenovirus E3-14.7K interacting protein 1
, Ras-related GTP-binding protein ragA