anti-RecQ Protein-Like 5 (RECQL5) Antibodies

The protein encoded by RECQL5 is a helicase that is important for genome stability. Additionally we are shipping RECQL5 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RECQL5 9400 O94762
RECQL5 170472  
RECQL5 287834  
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Top anti-RECQL5 Antibodies at antibodies-online.com

Showing 10 out of 67 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB RECQL5 Antibody (Center) (ABIN1881739) western blot analysis in human Uterus tissue lysates (35 µg/lane). This demonstrates the RECQL5 antibody detected the RECQL5 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: RECQL5 Antibody [NBP1-83438] - Staining of human cell line A-431 shows positivity in nucleus & cytoplasm. Immunohistochemistry-Paraffin: RECQL5 Antibody [NBP1-83438] - Staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IP, S, WB 100 μL Log in to see 7 to 9 Days
$486.94
Details
Human Rabbit Un-conjugated IP, WB 0.1 mL Log in to see 7 to 9 Days
$486.94
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: RECQL5 Antibody [NBP1-83437] - Staining of human cell line A-431 shows positivity in nucleus & nuclear membrane. Immunohistochemistry-Paraffin: RECQL5 Antibody [NBP1-83437] - Staining of human kidney shows strong membranous positivity in cells of tubules. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated WB RecQL5 antibody used at 0.25 ug/ml to detect target protein. 50 μg Log in to see 2 to 3 Days
$473.93
Details
Human Rabbit Un-conjugated WB Western blot analysis in human Uterus tissue lysates (35ug/lane). 400 μL Log in to see 2 to 3 Days
$515.63
Details

RECQL5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-RECQL5 Antibodies

  1. Human Polyclonal RECQL5 Primary Antibody for WB - ABIN1881739 : Schwendener, Raynard, Paliwal, Cheng, Kanagaraj, Shevelev, Stark, Sung, Janscak: Physical interaction of RECQ5 helicase with RAD51 facilitates its anti-recombinase activity. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for 1881739

  2. Human Polyclonal RECQL5 Primary Antibody for ICC, IF - ABIN4349789 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)
    Show all 2 references for 4349789

  3. Cow (Bovine) Polyclonal RECQL5 Primary Antibody for WB - ABIN2775189 : Garcia, Liu, Jiricny, West, Janscak: Human RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptide. in The EMBO journal 2004 (PubMed)

More Antibodies against RECQL5 Interaction Partners

Human RecQ Protein-Like 5 (RECQL5) interaction partners

  1. RECQ5 removes RAD51 (show RAD51 Antibodies) filaments stabilizing stalled replication forks at common fragile sites and hence facilitates CFS cleavage by MUS81 (show MUS81 Antibodies)-EME1 (show EME1 Antibodies).

  2. the open and closed forms of RECQL5 were used together with a quantitative comparison of all current RecQ family structures to construct a mechanistic model for RECQL5 helicase activity

  3. Study characterized the G-quadruplex (GQ) unfolding activity of RECQ5 for different DNA constructs under different salt conditions, showed that RECQ5 is overall a weak GQ destabilizer compared to Bloom and Werner

  4. interaction between RECQ5 and proliferating cell nuclear antigen (PCNA (show PCNA Antibodies)) promotes RAD18 (show RAD18 Antibodies)-dependent PCNA (show PCNA Antibodies) ubiquitination and the helicase activity of RECQ5 promotes the processing of replication intermediates.

  5. RECQL5 has unique strand annealing properties relative to the other human RecQ helicase proteins

  6. RECQL5 is a critical regulator of genome stability in myeloproliferative neoplasms and demonstrate that replication stress-associated cytotoxicity can be amplified specifically in JAK2V617F mutant cells through RECQL5-targeted synthetic lethality.

  7. Expression of RECQL5 in breast cancer can drive proliferation supporting an oncogenic function for RECQL5 in breast cancer. RECQL5 is a promising biomarker in breast cancer.

  8. RecQ5 prevents transcription associated genome instability by facilitating PIAS1 (show PIAS1 Antibodies)-SRSF1 (show SRSF1 Antibodies) ligase complex sumoylation of DNA topoisomerase 1 (show TOP1 Antibodies).

  9. results suggested RECQL5 as a tumor suppressor in osteosarcoma and may be a potential therapeutic target for osteosarcoma treatment

  10. PARylation is involved in the recruitment of RECQL5 and WRN to laser-induced DNA damage and RECQL5 and WRN have differential responses to PARylated PARP1 and Poly(ADP-ribose).

Mouse (Murine) RecQ Protein-Like 5 (RECQL5) interaction partners

  1. Recql5 protects the liver against LPS (show TLR4 Antibodies)/D-Gal (show GAL Antibodies)-induced injury by suppressing hepatocyte apoptosis and oxidative stress and modulation of CYP450 expression.

  2. Recql5 has a tumor suppressor role in the gastrointestinal tract of Apc (show APC Antibodies)(min) mice.

  3. Recql5-deficient cells exhibit elevated frequencies of spontaneous DNA double-strand breaks and homologous recombination (

  4. Data suggest that Recql5 helps maintain active DNA replication to prevent collapse of replication forks and accumulation of DSBs, preserve genome integrity and prevent cell death after replication stress due to topoisomerase I (show TOP1 Antibodies) poisoning.

RECQL5 Antigen Profile

Protein Summary

The protein encoded by this gene is a helicase that is important for genome stability. The encoded protein also prevents aberrant homologous recombination by displacing RAD51 from ssDNA. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RECQL5

  • RecQ protein-like 5 (RECQL5) antibody
  • RecQ protein-like 5 (recql5) antibody
  • RecQ protein-like 5 (LOC100225598) antibody
  • RecQ protein-like 5 (Recql5) antibody
  • DKFZp459N0627 antibody
  • RECQ5 antibody
  • Recq5b antibody
  • Recql5b antibody

Protein level used designations for RECQL5

ATP-dependent DNA helicase Q5 , RecQ protein-like 5 , ATP-dependent DNA helicase Q5-like , DNA helicase, RecQ-like type 5

GENE ID SPECIES
373891 Gallus gallus
454885 Pan troglodytes
566553 Danio rerio
702951 Macaca mulatta
100027279 Monodelphis domestica
100059566 Equus caballus
100173649 Pongo abelii
100216093 Xenopus (Silurana) tropicalis
100225598 Taeniopygia guttata
100397260 Callithrix jacchus
100469169 Ailuropoda melanoleuca
100544199 Meleagris gallopavo
9400 Homo sapiens
512590 Bos taurus
170472 Mus musculus
287834 Rattus norvegicus
483317 Canis lupus familiaris
100626380 Sus scrofa
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