RecQ Protein-Like 5 (RECQL5) ELISA Kits

The protein encoded by RECQL5 is a helicase that is important for genome stability. Additionally we are shipping RECQL5 Antibodies (67) and RECQL5 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human RECQL5 RECQL5 9400 O94762
Anti-Mouse RECQL5 RECQL5 170472  
Anti-Rat RECQL5 RECQL5 287834  
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More ELISA Kits for RECQL5 Interaction Partners

Human RecQ Protein-Like 5 (RECQL5) interaction partners

  1. the open and closed forms of RECQL5 were used together with a quantitative comparison of all current RecQ family structures to construct a mechanistic model for RECQL5 helicase activity

  2. Study characterized the G-quadruplex (GQ) unfolding activity of RECQ5 for different DNA constructs under different salt conditions, showed that RECQ5 is overall a weak GQ destabilizer compared to Bloom and Werner

  3. interaction between RECQ5 and proliferating cell nuclear antigen (PCNA (show PCNA ELISA Kits)) promotes RAD18 (show RAD18 ELISA Kits)-dependent PCNA (show PCNA ELISA Kits) ubiquitination and the helicase activity of RECQ5 promotes the processing of replication intermediates.

  4. RECQL5 has unique strand annealing properties relative to the other human RecQ helicase proteins

  5. RECQL5 is a critical regulator of genome stability in myeloproliferative neoplasms and demonstrate that replication stress-associated cytotoxicity can be amplified specifically in JAK2V617F mutant cells through RECQL5-targeted synthetic lethality.

  6. Expression of RECQL5 in breast cancer can drive proliferation supporting an oncogenic function for RECQL5 in breast cancer. RECQL5 is a promising biomarker in breast cancer.

  7. RecQ5 prevents transcription associated genome instability by facilitating PIAS1 (show PIAS1 ELISA Kits)-SRSF1 (show SRSF1 ELISA Kits) ligase complex sumoylation of DNA topoisomerase 1 (show TOP1 ELISA Kits).

  8. results suggested RECQL5 as a tumor suppressor in osteosarcoma and may be a potential therapeutic target for osteosarcoma treatment

  9. PARylation is involved in the recruitment of RECQL5 and WRN to laser-induced DNA damage and RECQL5 and WRN have differential responses to PARylated PARP1 and Poly(ADP-ribose).

  10. The RECQL5 genetic polymorphism was associated with osteosarcoma in a Chinese population.

Mouse (Murine) RecQ Protein-Like 5 (RECQL5) interaction partners

  1. Recql5 protects the liver against LPS (show TLR4 ELISA Kits)/D-Gal (show GAL ELISA Kits)-induced injury by suppressing hepatocyte apoptosis and oxidative stress and modulation of CYP450 expression.

  2. Recql5 has a tumor suppressor role in the gastrointestinal tract of Apc (show APC ELISA Kits)(min) mice.

  3. Recql5-deficient cells exhibit elevated frequencies of spontaneous DNA double-strand breaks and homologous recombination (

  4. Data suggest that Recql5 helps maintain active DNA replication to prevent collapse of replication forks and accumulation of DSBs, preserve genome integrity and prevent cell death after replication stress due to topoisomerase I (show TOP1 ELISA Kits) poisoning.

RECQL5 Antigen Profile

Antigen Summary

The protein encoded by this gene is a helicase that is important for genome stability. The encoded protein also prevents aberrant homologous recombination by displacing RAD51 from ssDNA. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RecQ Protein-Like 5 (RECQL5) ELISA Kits

  • RecQ protein-like 5 (RECQL5) antibody
  • RecQ protein-like 5 (recql5) antibody
  • RecQ protein-like 5 (LOC100225598) antibody
  • RecQ protein-like 5 (Recql5) antibody
  • DKFZp459N0627 antibody
  • RECQ5 antibody
  • Recq5b antibody
  • Recql5b antibody

Protein level used designations for RecQ Protein-Like 5 (RECQL5) ELISA Kits

ATP-dependent DNA helicase Q5 , RecQ protein-like 5 , ATP-dependent DNA helicase Q5-like , DNA helicase, RecQ-like type 5

GENE ID SPECIES
373891 Gallus gallus
454885 Pan troglodytes
566553 Danio rerio
702951 Macaca mulatta
100027279 Monodelphis domestica
100059566 Equus caballus
100173649 Pongo abelii
100216093 Xenopus (Silurana) tropicalis
100225598 Taeniopygia guttata
100397260 Callithrix jacchus
100469169 Ailuropoda melanoleuca
100544199 Meleagris gallopavo
9400 Homo sapiens
512590 Bos taurus
170472 Mus musculus
287834 Rattus norvegicus
483317 Canis lupus familiaris
100626380 Sus scrofa
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