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Receptor (G Protein-Coupled) Activity Modifying Protein 2 Proteins (RAMP2)

The protein encoded by RAMP2 is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). Additionally we are shipping RAMP2 Antibodies (50) and RAMP2 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RAMP2 54409 Q9WUP0
RAMP2 58966 Q9JHJ1
RAMP2 10266 O60895
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Top RAMP2 Proteins at antibodies-online.com

Showing 7 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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Yeast Guinea Pig His tag   1 mg Log in to see 56 to 66 Days
$2,185.33
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Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,196.33
Details

RAMP2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Rat (Rattus)

Human , ,
, ,

More Proteins for Receptor (G Protein-Coupled) Activity Modifying Protein 2 (RAMP2) Interaction Partners

Mouse (Murine) Receptor (G Protein-Coupled) Activity Modifying Protein 2 (RAMP2) interaction partners

  1. RAMP2 is essential for early vascular development and knockout-mice die in utero.

  2. These results indicate the AM-RAMP2 system works to protect nerve cells from both acute and chronic cerebral ischemia by maintaining cerebral blood flow suppressing oxidative stress, and in the case of chronic ischemia, enhancing capillary growth.

  3. The AM-RAMP2 system is a key determinant of vascular integrity and homeostasis from prenatal stages through adulthood.

  4. These data demonstrate that the adrenomedullin (show ADM Proteins)-RAMP2 system is essential for cardiac metabolism and homeostasis.

  5. Data show that mechanical ventilation reduced the expression of receptor activity-modifying protein RAMP3 (show RAMP3 Proteins), but not of intermedin (IMD (show ADM2 Proteins)), calcitonin receptor-like receptor (CRLR (show CALCRL Proteins)), and RAMP1 (show RAMP1 Proteins) and RAMP2.

  6. Adrenomedullin (show ADM Proteins)-RAMP2 system is the potential target for the induction of liver sinusoidal endothelial cells.

  7. this work reveals an essential role for RAMP2 in endocrine physiology and provides the first in vivo evidence for a physiological role of RAMP2 beyond that of AM/CLR (show CALCR Proteins) signaling

  8. role in cell surface expression of CRLR (show CALCRL Proteins)/RAMP heterodimeric receptors

  9. RAMP2 plays a key role in the sensitivity and potency of AM-induced hypotensive responses via the AM1 receptor.

  10. RAMP2 and RAMP3 (show RAMP3 Proteins) have distinct physiological functions throughout embryogenesis, adulthood, and old age

Human Receptor (G Protein-Coupled) Activity Modifying Protein 2 (RAMP2) interaction partners

  1. This study reveals the glucagon receptor (show GCGR Proteins) as a previously unidentified target for GLP-1 receptor (show GLP1R Proteins) agonists and highlights a role for RAMP2 in regulating its pharmacology.

  2. Data suggest that ligand binding of a G protein-coupled receptor (GPCR (show TAS1R3 Proteins)) may inform drug development targeting calcitonin receptor-like receptor (CLR (show CALCRL Proteins)):receptor activity-modifying proteins RAMP1 (show RAMP1 Proteins)/2 complexes.

  3. the AM system is widely expressed in human thymus from newborns; both AM1 receptor components CLR (show DCLK3 Proteins) and RAMP2, but not RAMP3 (show RAMP3 Proteins), are not associated with the plasma membrane of TECs and thymocytes but are located intracellularly, notably in the nucleus

  4. Adrenomedullin (show ADM Proteins)-RAMP2 system suppresses ER stress-induced tubule cell death and is involved in kidney protection.

  5. Data suggest isoforms of RAMP modulate accessibility of peptides to residues situated on CALCRL (calcitonin receptor-like receptor (show CALCRL Proteins)) N-terminal domain; RAMP3 (show RAMP3 Proteins)/RAMP2/RAMP1 (show RAMP1 Proteins) appear to alter accessibility of specific residues at CALCRL (show CALCRL Proteins)-RAMP interface.

  6. RAMP2 gene expression increases with gestational age development in the fetal lung.

  7. The CRLR (show CALCRL Proteins)-RAMP2 interactions were confirmed for the full-length proteins on the cell surface by site-specific photo-crosslinking.

  8. the hCRLR C-tail is crucial for adrenomedullin-evoked cAMP production and internalization of the CRLR/RAMP2, while the receptor internalization is dependent on the aforementioned GPCR kinases, but not Gs coupling.

  9. results show the presence of calcitonin receptor-like receptor (show CALCRL Proteins) and receptor activity-modifying proteins in middle meningeal, middle cerebral, pial, and superficial temporal vessels

  10. Co-expression of calcitonin (show CALCA Proteins) receptors (CT) lacking a portion of domain 1 with receptor activity-modifying protein (RAMP) 1 (show RAMP1 Proteins), 2, or 3 appears to produce functional CT-(8 (show SYCP1 Proteins)-32)-sensitive adrenomedullin (show ADM Proteins) receptors.

Cow (Bovine) Receptor (G Protein-Coupled) Activity Modifying Protein 2 (RAMP2) interaction partners

  1. Data indicate that adrenomedullin (show ADM Proteins) mRNA and protein signal were only found in trophoblast binucleate cells (BNCs), whereas those of CRLR (show CALCRL Proteins), RAMP2 and RAMP3 (show RAMP3 Proteins) were detected in cotyledonary villous and caruncular epithelial cells.

RAMP2 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface.

Gene names and symbols associated with RAMP2

  • receptor (G protein-coupled) activity modifying protein 2 (RAMP2)
  • receptor (G protein-coupled) activity modifying protein 2 (ramp2)
  • receptor (G protein-coupled) activity modifying protein 2 (LOC100224587)
  • receptor (calcitonin) activity modifying protein 2 (Ramp2)
  • receptor (G protein-coupled) activity modifying protein 2 (Ramp2)
  • RAMP2 protein
  • zgc:174936 protein

Protein level used designations for RAMP2

receptor (calcitonin) activity modifying protein 2 , receptor activity modifying protein 2 , receptor activity-modifying protein 2 , receptor (G protein-coupled) activity modifying protein 2 , receptor activity modifying protein 2 isoform , CRLR activity-modifying protein 2 , calcitonin receptor-like receptor activity modifying protein 2 , calcitonin-receptor-like receptor activity-modifying protein 2 , receptor-activity-modifying protein 2

GENE ID SPECIES
420022 Gallus gallus
480515 Canis lupus familiaris
566313 Danio rerio
707718 Macaca mulatta
100224587 Taeniopygia guttata
54409 Mus musculus
100135611 Cavia porcellus
58966 Rattus norvegicus
10266 Homo sapiens
454698 Pan troglodytes
397155 Sus scrofa
504230 Bos taurus
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