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REEP2 encodes a member of the receptor expression enhancing protein family. Additionally we are shipping REEP2 Proteins (3) and many more products for this protein.
Showing 10 out of 57 products:
Mouse (Murine) Monoclonal REEP2 Primary Antibody for ICC, IF - ABIN2485645
Ilegems, Iwatsuki, Kokrashvili, Benard, Ninomiya, Margolskee: REEP2 enhances sweet receptor function by recruitment to lipid rafts. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2010
Human Polyclonal REEP2 Primary Antibody for EIA, IHC (p) - ABIN500579
Saito, Kubota, Roberts, Chi, Matsunami: RTP family members induce functional expression of mammalian odorant receptors. in Cell 2004
Expression of the REEP1 (show REEP1 Antibodies)/REEP2 subfamily appears to be restricted to neuronal and neuronal-like exocytotic tissues, consistent with neuronally restricted symptoms of REEP1 (show REEP1 Antibodies) genetic disorders.
We have identified mutations in REEP2 in two families with relatively pure, early-onset hereditary spastic paraplegia, one with autosomal-dominant and the other with autosomal-recessive transmission.
In mouse, Reep2 enhances sweet receptor function by a different mechanism than Reep1 uses to enhance olfactory receptor function.
REEP2 recruits sweet receptors into lipid raft microdomains localized near the taste cell's apical region, thereby improving G-protein-coupled receptor (show GPR34 Antibodies) signaling and promoting receptor access to tastants arriving through the apical taste pore.
This gene encodes a member of the receptor expression enhancing protein family. Studies of a related gene in mouse suggest that the encoded protein is found in the cell membrane and enhances the function of sweet taste receptors. Alternative splicing results in multiple transcript variants.
receptor expression-enhancing protein 2