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anti-Receptor-Associated Protein of The Synapse (RAPSN) Antibodies

RAPSN encodes a member of a family of proteins that are receptor associated proteins of the synapse. Additionally we are shipping Receptor-Associated Protein of The Synapse Proteins (8) and Receptor-Associated Protein of The Synapse Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RAPSN 5913 Q13702
RAPSN 19400 P12672
RAPSN 362161  
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Top anti-Receptor-Associated Protein of The Synapse Antibodies at antibodies-online.com

Showing 10 out of 40 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-RAPSN Antibody Titration: 0.2-1 ug/mlPositive Control: Jurkat cell lysate WB Suggested Anti-RAPSN  Antibody Titration: 0.2-1 µg/mL  Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated EIA, WB   0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Skeletal Muscle (formalin-fixed, paraffin-embedded) stained with RAPSN antibody ABIN337353 at 10-20 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with RAPSN antibody ABIN337346 at 10-20 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Dog Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB RAPSN antibody used at 0.25 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details

RAPSN Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Rat (Rattus) ,
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Top referenced anti-Receptor-Associated Protein of The Synapse Antibodies

  1. Chicken Polyclonal RAPSN Primary Antibody for WB - ABIN2775693 : Müller, Abicht, Christen, Stucka, Schara, Mortier, Huebner, Lochmüller: A newly identified chromosomal microdeletion of the rapsyn gene causes a congenital myasthenic syndrome. in Neuromuscular disorders : NMD 2004 (PubMed)

  2. Human Polyclonal RAPSN Primary Antibody for EIA, WB - ABIN401664 : Banwell, Ohno, Sieb, Engel: Novel truncating RAPSN mutations causing congenital myasthenic syndrome responsive to 3,4-diaminopyridine. in Neuromuscular disorders : NMD 2004 (PubMed)

More Antibodies against Receptor-Associated Protein of The Synapse Interaction Partners

Human Receptor-Associated Protein of The Synapse (RAPSN) interaction partners

  1. These findings uncover a new link between rapsyn, lysosome positioning, exocytosis and plasma membrane integrity.

  2. a mutation of the RAPSN gene may have a role in development of congenital myasthenic syndrome after general anaesthesia [case report]

  3. Investigation of mutations in RAPSN determines that patients with congenital myasthenic syndrome can be misdiagnosed with seronegative myasthenia gravis.

  4. An allelic quantification on patient's DNA identified three novel multi-exon deletions of RAPSN.

  5. nAChR (show CHRNA4 Antibodies) mobility in plasma membranes of myoblast cells during their differentiation to myotubes in the presence and absence of rapsyn

  6. Rapsyn mutations in humans cause endplate acetylcholine-receptor deficiency and myasthenic syndrome

  7. E-box mutations in the RAPSN promoter region may have a role in congenital myasthenic syndrome

  8. Four patients from four different families with RAPSN mutations and congenital myasthenic syndrome

  9. Rapsyn is essential for clustering the acetylcholine receptor at the postsynaptic membrane of the neuromuscular junction.

  10. recombination events may have occurred within the rapsyn gene and that this may have implications in the phenotypic expression of postsynaptic congenital myasthenic syndrome

Mouse (Murine) Receptor-Associated Protein of The Synapse (RAPSN) interaction partners

  1. Protein kinase CK2 (show CSNK2A1 Antibodies) interacts at the neuromuscular synapse with Rapsyn, Rac1, 14-3-3gamma (show YWHAG Antibodies), and Dok-7 (show DOK7 Antibodies) proteins and phosphorylates the latter two.

  2. Plectin (show PLEC Antibodies) bridges acetylcholine receptors and intermediate filaments via direct interaction with the AChR-scaffolding protein rapsyn in an isoform-specific manner.

  3. Molecular modelling, immunoprecipitation and bimolecular fluorescence complementation approaches identify an alpha-helical stretch of rapsyn to be crucial for binding to the dimerisation and docking domain of PKA type I.

  4. typical anchoring proteins of central excitatory synapses coimmunoprecipitate and colocalize with rapsyn

  5. alpha-Actinin (show ACTN1 Antibodies), rapsyn, and surface AChR form a ternary complex.

  6. nAChR (show CHRNA4 Antibodies) mobility in plasma membranes of myoblast cells during their differentiation to myotubes in the presence and absence of rapsyn

  7. These results provide the first experimental evidence that rapsyn is a direct sequence-specific target of Kaiso (show ZBTB33 Antibodies) and delta-catenin (show CTNND2 Antibodies).

  8. Thus, the metabolic half-life of receptors at the synapse may be modulated by local changes in the subsynaptic ratio of rapsyn to AChR.

  9. Remarkable dynamism of rapsyn underlies stability and maintenance of the postsynaptic scaffold and suggests that the insertion of different postsynaptic proteins may be operating independently.

  10. Developmental increase in the amount of rapsyn per acetylcholine receptor promotes postsynaptic receptor packing and stability.

Receptor-Associated Protein of The Synapse (RAPSN) Antigen Profile

Protein Summary

This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with RAPSN

  • receptor-associated protein of the synapse (RAPSN) antibody
  • receptor-associated protein of the synapse (rapsn) antibody
  • receptor-associated protein of the synapse (Rapsn) antibody
  • receptor-associated protein of the synapse, 43kD (rapsn) antibody
  • 43kDa antibody
  • Nraps antibody
  • Raps antibody
  • RAPSN antibody
  • rapsyn antibody
  • RNF205 antibody

Protein level used designations for RAPSN

receptor-associated protein of the synapse , 43 kD receptor-associated protein of the synapse , 43 kDa receptor-associated protein of the synapse-like , 43 kDa postsynaptic protein , 43 kDa receptor-associated protein of the synapse , acetylcholine receptor-associated 43 kDa protein , rapsyn , receptor-associated protein of the synapse, 43kD , 43 kda postsynaptic protein , RING finger protein 205 , acetylcholine receptor-associated 43 kda protein , 43kDa acetylcholine receptor-associated protein , receptor-associated protein of the synapse, 43 kDa , twitch once , two

GENE ID SPECIES
451705 Pan troglodytes
100051540 Equus caballus
100397914 Callithrix jacchus
100447845 Pongo abelii
100579467 Nomascus leucogenys
399137 Xenopus laevis
395986 Gallus gallus
5913 Homo sapiens
609725 Canis lupus familiaris
541061 Bos taurus
19400 Mus musculus
362161 Rattus norvegicus
352942 Danio rerio
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