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Receptor-Interacting serine-threonine Kinase 3 Proteins (RIPK3)

The product of RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. Additionally we are shipping RIPK3 Antibodies (153) and RIPK3 Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RIPK3 11035 Q9Y572
RIPK3 56532  
RIPK3 246240 Q9Z2P5
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Top RIPK3 Proteins at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Mouse His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$767.80
Details
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$803.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Mouse His tag   1 mg Log in to see 56 to 66 Days
$3,375.17
Details
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$322.08
Details
HOST_Escherichia coli (E. coli) Cow Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details

RIPK3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine) ,
,
Rat (Rattus)

Top referenced RIPK3 Proteins

  1. Human RIPK3 Protein expressed in Wheat germ - ABIN1318116 : Northington, Chavez-Valdez, Graham, Razdan, Gauda, Martin: Necrostatin decreases oxidative damage, inflammation, and injury after neonatal HI. in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2011 (PubMed)

More Proteins for Receptor-Interacting serine-threonine Kinase 3 (RIPK3) Interaction Partners

Human Receptor-Interacting serine-threonine Kinase 3 (RIPK3) interaction partners

  1. CHIP is a bona fide negative regulator of the RIPK1 (show RIPK1 Proteins)-RIPK3 necrosome formation leading to desensitization of TNF (show TNF Proteins)-mediated necroptosis

  2. CNOT3 (show CNOT3 Proteins) suppression promotes necroptosis by stabilizing mRNAs for cell death-inducing proteins, Ripk1 (show RIPK1 Proteins) and Ripk3.

  3. RIPK3 expression may allow unmasking the necroptotic signalling machinery in melanoma and points to reactivation of this pathway as a treatment option for metastatic melanoma.

  4. Additionally, later in infection, RIP3 is cleaved by the coxsackievirus B3-encoded cysteine protease (show CTSB Proteins) 3C(pro), which serves to abrogate RIP3-mediated necrotic signaling and induce a nonnecrotic form of cell death.

  5. Results identify a crucial role for RIPK3-PGAM5 (show PGAM5 Proteins)-Drp1 (show CRMP1 Proteins)/NFAT (show NFATC1 Proteins) signalling in NKT (show SLC22A6 Proteins) cell activation, and further suggest that RIPK3-PGAM5 (show PGAM5 Proteins) signalling may mediate crosstalk between mitochondrial function and immune signalling.

  6. although JNK (show MAPK8 Proteins) activation and RIP3 expression are induced by FS, neither contributes to the liver injury.

  7. The RIP3 expression is reduced in tumors compared to normal tissue in 85% of breast cancer patients, suggesting that RIP3 deficiency is positively selected during tumor growth/development.

  8. Data implicate the infiltrating macrophages as a source of damaging inflammasomes after photoreceptor detachment in a RIP3-dependent manner and suggest a novel therapeutic target for treatment of retinal diseases.

  9. PolyIC stimulation of cervical cancer cells induced necroptotic cell death, which was strictly dependent on the expression of the receptor-interacting protein (show RIPK1 Proteins) kinase (show CDK7 Proteins) RIPK3.

  10. Data suggest that neoalbaconol-induced necroptosis include receptor interacting serine/threonine kinase (show TLK2 Proteins) 1-dependent expression of tumor necrosis factor alpha (show TNF Proteins) and receptor interacting serine/threonine kinase 3-dependent generation of reactive oxygen species.

Mouse (Murine) Receptor-Interacting serine-threonine Kinase 3 (RIPK3) interaction partners

  1. we demonstrate that the phosphorylation of Ser345 is not required for the interaction between RIPK3 and MLKL in the necrosome, but is essential for MLKL translocation, accumulation in the plasma membrane, and consequent necroptosis.

  2. CHIP is a bona fide negative regulator of the RIPK1 (show RIPK1 Proteins)-RIPK3 necrosome formation leading to desensitization of TNF (show TNF Proteins)-mediated necroptosis

  3. Data indicate that receptor-interacting serine-threonine kinase 3 (RIPK3) deletion prevents inflammatory phenotypes in CreLysM (lysozyme (show LYZ Proteins) M) Casp8fl/fl (caspase 8 (show CASP8 Proteins)) mice.

  4. RIP3-induced activation of CaMKII (show CAMK2G Proteins), via phosphorylation or oxidation or both, triggers opening of the mitochondrial permeability transition pore and myocardial necroptosis.

  5. RIPK3 is an essential molecule to maintain the temporal manner of the normal progression of wound closure

  6. deficiency of RIPK3 or MLKL prevents oxalate crystal-induced acute kidney injury.

  7. Results identify a crucial role for RIPK3-PGAM5 (show PGAM5 Proteins)-Drp1 (show CRMP1 Proteins)/NFAT (show NFATC1 Proteins) signalling in NKT (show CTSL1 Proteins) cell activation, and further suggest that RIPK3-PGAM5 (show PGAM5 Proteins) signalling may mediate crosstalk between mitochondrial function and immune signalling.

  8. although JNK (show MAPK8 Proteins) activation and RIP3 expression are induced by FS, neither contributes to the liver injury.

  9. RIPK3 can promote NLRP3 inflammasome and IL-1beta inflammatory responses independent of MLKL and necroptotic cell death

  10. Data implicate the infiltrating macrophages as a source of damaging inflammasomes after photoreceptor detachment in a RIP3-dependent manner and suggest a novel therapeutic target for treatment of retinal diseases.

RIPK3 Protein Profile

Protein Summary

The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.

Gene names and symbols associated with RIPK3

  • receptor-interacting serine-threonine kinase 3 (RIPK3)
  • receptor-interacting serine-threonine kinase 3 (ripk3)
  • receptor-interacting serine-threonine kinase 3 (Ripk3)
  • 2610528K09Rik protein
  • AW107945 protein
  • Hcyp2 protein
  • Rip3 protein
  • RIPK3 protein

Protein level used designations for RIPK3

receptor-interacting serine-threonine kinase 3 , receptor-interacting serine/threonine-protein kinase 3-like , RIP-3 , RIP-like protein kinase 3 , receptor interacting protein 3 , receptor-interacting protein 3 , receptor-interacting serine/threonine-protein kinase 3 , mRIP3 , homocysteine respondent protein HCYP2

GENE ID SPECIES
452820 Pan troglodytes
100461174 Pongo abelii
733239 Xenopus laevis
11035 Homo sapiens
56532 Mus musculus
246240 Rattus norvegicus
608486 Canis lupus familiaris
507427 Bos taurus
100734737 Cavia porcellus
Selected quality suppliers for RIPK3 Proteins (RIPK3)
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