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Might act as an inhibitor of spontaneous calcium carbonate precipitation.. Additionally we are shipping Regenerating Islet-Derived 2 Antibodies (3) and and many more products for this protein.
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Normal expression of Reg2 (show FLOT1 Proteins) gene is required for appropriate compensations in pancreatic islet proliferation and expansion in response to obesity and aging.
mReg2 inhibits AIF (show AIFM1 Proteins)-mediated apoptosis by promoting the nuclear presence of Scythe (show BAT3 Proteins) and inducing hsp70 (show HSP70 Proteins).
Reg2 (show FLOT1 Proteins) induces glucose-regulated peptide 78 (GRP78 (show HSPA5 Proteins)) expression via the Akt (show AKT1 Proteins)-mTORC1 axis.
Direct stimulation of Reg2 (show FLOT1 Proteins) and Reg3beta genes by glucocorticoids.
Reg2 (show FLOT1 Proteins), Reg3alpha, and Reg3beta were abundantly expressed in most acinar cells of the pancreas with clear age-dependent and isoform-specific patterns.
Reg2 (show FLOT1 Proteins) protects MIN6 cells from streptozotocin-induced apoptosis by attenuating streptozotocin's ability to disrupt mitochondrial membrane integrity, activate caspase-3 (show CASP3 Proteins) and promote poly-ADP ribose polymerase (show PARP1 Proteins) cleavage, and induce apoptosis.
adjuvant immunotherapy regulates type 1 diabetes in diabetic mice and induces Reg2 (show FLOT1 Proteins)-mediated regeneration of beta cells
Overexpression of Reg2 gene offered no protection against streptozotocin-induced beta-cell damage and diabetes and did not protect acinar cells against caerulein-induced acute pancreatitis.
Reg2 (show FLOT1 Proteins) deficiency enhanced liver sensitivity to Fas (show FAS Proteins)-induced oxidative stress and delayed liver regeneration with persistent TNF-alpha (show TNF Proteins)/IL6 (show IL6 Proteins)/STAT3 (show STAT3 Proteins) signaling.
Reg-II is a likely mouse exocrine pancreas cytoprotective candidate protein whose expression is regulated by keratin filament organization and phosphorylation
Might act as an inhibitor of spontaneous calcium carbonate precipitation.
, islet of Langerhans regenerating protein 2
, pancreatic stone protein 2
, pancreatic thread protein 2
, regenerating islet-derived, mouse homolog 2