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Required for completion of mitosis and cytokinesis (By similarity). Additionally we are shipping Regulator of Chromosome Condensation 2 Proteins (3) and many more products for this protein.
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Cow (Bovine) Polyclonal RCC2 Primary Antibody for IP, WB - ABIN2787157
Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006
Impaired RCC2 affects functional and clinical endpoints of colorectal cancer. High-risk patients with either MSI (show MSI1 Antibodies) or MSS (show SIL1 Antibodies) tumors can be identified with cost-effective routine RCC2 assays.
RCC2 exhibits guanine exchange factor activity, in vitro and in cells, for the small GTPase (show RACGAP1 Antibodies) RalA (show rala Antibodies). RCC2 and RalA (show rala Antibodies) apparently work together to contribute to the regulation of kinetochore-microtubule interactions in early mitosis.
MiR (show MLXIP Antibodies)-29c is downregulated in gastric carcinomas and regulates cell proliferation by targeting RCC2.
TD-60 is an essential regulator of cell cycle (show C13orf15 Antibodies) progression during interphase.
a complex containing cortactin (show CTTN Antibodies) and RCC2/TD60 complex that may play a functional role in cells undergoing mitosis.
Studies indicated that DDX21 (show DDX21 Antibodies), HNRNPC (show HNRNPC Antibodies), and RCC2 were isolated from Ku86 (show XRCC5 Antibodies) multicomponent complex in response to DNA damage.
Data show that TD-60 is a member of the RCC1 family and that it binds preferentially the nucleotide-free form of the small G protein Rac1.
Dysregulation of Rac1 and Arf6 (show ARF6 Antibodies) function by RCC2 knockdown also abolished persistent migration along fibronectin (show FN1 Antibodies) fibers, indicating a functional role for RCC2 in directional cell movement.
Required for completion of mitosis and cytokinesis (By similarity).
regulator of chromosome condensation 2
, RCC1-like protein TD-60
, protein RCC2
, telophase disk protein of 60 kDa
, protein RCC2 homolog
, telophase disc 60 kDa protein