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Regulator of G-Protein Signaling 14 (RGS14) ELISA Kits

RGS14 encodes a member of the regulator of G-protein signaling family. Additionally we are shipping RGS14 Antibodies (84) and RGS14 Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human RGS14 RGS14 10636 O43566
Anti-Mouse RGS14 RGS14 51791 P97492
Anti-Rat RGS14 RGS14 114705 O08773
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More ELISA Kits for RGS14 Interaction Partners

Human Regulator of G-Protein Signaling 14 (RGS14) interaction partners

  1. The RBD (show CACNA1D ELISA Kits) region associates with the RGS (show PITX2 ELISA Kits) domain region, producing an intramolecular interaction within RGS14 that enhances the GTPase (show RACGAP1 ELISA Kits) activating function.

  2. RGS14 can form complexes with GPCRs in cells that are dependent on Galpha (show SUCLG1 ELISA Kits)(i/o) and these RGS14.Galpha (show SUCLG1 ELISA Kits)(i1).GPCR (show NMUR1 ELISA Kits) complexes may be substrates for other signaling partners such as Ric-8A (show RIC8A ELISA Kits)

  3. RGS-14 may facilitate cognitive processing by modulating Cav1 (show CAV1 ELISA Kits) channel-mediated intracellular divalent calcium ion Ca(2 (show CA2 ELISA Kits))+ transients.

  4. RGS14 serves as a novel scaffold to integrate GTP-Binding Protein alpha Subunit (show POLG ELISA Kits) and Ras/Raf (show RAF1 ELISA Kits)/MAPkinase signalling events through the action of its GL domain.

  5. We show that RGS14 is a component of mitotic asters formed in vitro from HeLa cell extracts and that depletion of RGS14 from cell extracts blocks aster formation.

  6. NMR 1H, 13C and 15N resonances of the RGS (show PITX2 ELISA Kits) domain (residues 56-207)

Mouse (Murine) Regulator of G-Protein Signaling 14 (RGS14) interaction partners

  1. Study shows that RGS14 (show RGS16 ELISA Kits) mRNA and protein are upregulated throughout postnatal mouse development, and RGS14 (show RGS16 ELISA Kits) protein exhibits a dynamic localization pattern that is enriched in hippocampus and primary olfactory cortex in the adult mouse brain

  2. Inactive Galpha(i1)-GDP enhances the affinity of RGS14 for H-Ras-GTP in live cells, resulting in a ternary signaling complex that is further regulated by G protein-coupled receptors.

  3. Activation of the Rsg14-Galphai1-GDP signaling complex is regulated by Ric8 (show RIC8A ELISA Kits).

  4. These results demonstrate that RGS14 (show RGS16 ELISA Kits) is a key regulator of signaling pathways linking synaptic plasticity in CA2 (show CA2 ELISA Kits) pyramidal neurons to hippocampal-based learning and memory but distinct from the canonical DG-CA3 (show CA3 ELISA Kits)-CA1 (show CA1 ELISA Kits) circuit.

  5. the RGS14 (show RGS16 ELISA Kits) GoLoco domain discriminates among Galphai isoforms

  6. RGS14 (show RGS16 ELISA Kits) is found ubiquitously throughout the postimplantation period in mice

  7. RGS14 (show RGS16 ELISA Kits) activity towards heterotrimeric G-proteins, as either a GAP or a guanine nucleotide dissociation inhibitor, was unaffected by Rap (show LRPAP1 ELISA Kits) binding.

  8. Morphine activation of Mu opioid receptors RGS14 (show RGS16 ELISA Kits) prevents G-protein-coupled receptor (show GPR34 ELISA Kits) kinases from phosphorylating those residues required for receptor endocytosis.

RGS14 Antigen Profile

Antigen Summary

This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Gene names and symbols associated with RGS14

  • regulator of G-protein signaling 14 (rgs14) antibody
  • regulator of G-protein signaling 14 (RGS14) antibody
  • Regulator of G-protein signaling 14 (rgs14) antibody
  • regulator of G-protein signaling 14 (Rgs14) antibody
  • MGC80558 antibody
  • rgs14 antibody
  • RPIP1 antibody

Protein level used designations for RGS14

regulator of G-protein signaling 14 , regulator of G-protein signalling 14 , Regulator of G-protein signaling 14 , regulator of G-protein signaling 14-like , RAP1/RAP2-interacting protein , rap1/rap2 interacting protein

GENE ID SPECIES
444133 Xenopus laevis
471758 Pan troglodytes
489092 Canis lupus familiaris
532605 Bos taurus
699625 Macaca mulatta
769193 Gallus gallus
100195412 Salmo salar
100404112 Callithrix jacchus
100476010 Ailuropoda melanoleuca
100524790 Sus scrofa
100585478 Nomascus leucogenys
10636 Homo sapiens
51791 Mus musculus
114705 Rattus norvegicus
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