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Regulator of Telomere Elongation Helicase 1 (RTEL1) ELISA Kits

In mice, inactivation of the Rtel (regulator of telomere length) gene has been shown to cause chromosome breaks, fusions, and telomere loss. Additionally we are shipping RTEL1 Antibodies (12) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human RTEL1 RTEL1 51750 Q9NZ71
Anti-Mouse RTEL1 RTEL1 269400 Q0VGM9
Anti-Rat RTEL1 RTEL1 362288 Q5RJZ1
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More ELISA Kits for RTEL1 Interaction Partners

Arabidopsis thaliana Regulator of Telomere Elongation Helicase 1 (RTEL1) interaction partners

  1. The RTEL1 homolog in Arabidopsis thaliana plays multiple roles in preserving genome stability.

Human Regulator of Telomere Elongation Helicase 1 (RTEL1) interaction partners

  1. Deletion in the RTEL1 gene is associated with metastatic glioblastoma.

  2. Heterozygous RTEL1 mutations are responsible for familial pulmonary fibrosis (FPF (show TNFRSF1A ELISA Kits)) and, thereby, extend the clinical spectrum of RTEL1 deficiency. Thus, RTEL1 enlarges the number of telomere-associated genes implicated in FPF (show TNFRSF1A ELISA Kits).

  3. results suggest a significant association between the RETL1, TREH, and PHLDB1 genes and GBM development in the Han Chinese population

  4. A homozygous mutation of RTEL1 in a child presenting with an apparently isolated natural killer cell deficiency.

  5. RTEL1 single nucleotide polymorphisms are associated with decreased susceptibility to pediatric brain astrocytoma.

  6. Association between the RTEL1 rs6010620 polymorphism and glioma risk was significant. [Meta-Analysis]

  7. PARN (show PARN ELISA Kits) and RTEL1 mutation carriers had shortened leukocyte telomere lengths.

  8. This work unravels completely unanticipated roles for RTEL1 in RNP (show RNPC3 ELISA Kits) trafficking and strongly suggests that defects in RNP (show RNPC3 ELISA Kits) biogenesis pathways contribute to the pathology of Hoyeraal-Hreidarsson syndrome

  9. rs6010620 polymorphism in the RTEL1 gene is associated with increased risk of glioma in both Caucasians and Asians. [Meta-Analysis]

  10. Rare loss-of-function variants in RTEL1 represent a newly defined genetic predisposition for FIP (show USF2 ELISA Kits), supporting the importance of telomere-related pathways in pulmonary fibrosis.

Mouse (Murine) Regulator of Telomere Elongation Helicase 1 (RTEL1) interaction partners

  1. RTEL1 plays a critical role in both telomere and genome-wide replication, which is crucial for genetic stability and tumor avoidance.

  2. Upregulated RTEL1 is tumorigenic and is able to initiate the formation of hepatocellular carcinoma in mice.

  3. RTEL1 performs two distinct functions at telomeres: it disassembles T loops and also counteracts telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.

Cow (Bovine) Regulator of Telomere Elongation Helicase 1 (RTEL1) interaction partners

  1. Cloned a bovine regulator of telomere length elongation helicase (show DNA2 ELISA Kits) (RTEL) homolog and characterized its gene structure, expression distribution, splice variants and profile of DNA methylation (show HELLS ELISA Kits) around two putative transcription start sites.

RTEL1 Antigen Profile

Antigen Summary

In mice, inactivation of the Rtel (regulator of telomere length) gene has been shown to cause chromosome breaks, fusions, and telomere loss. In addition, Rtel is required for telomere elongation. Therefore, the mouse Rtel gene regulates chromosome stability and telomere length. This gene is the human ortholog of the mouse Rtel gene, so its protein product may play similar roles in humans. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, decoy (TNFRSF6B), generates a non-coding transcript. Multiple transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with RTEL1

  • regulator of telomere elongation helicase 1 (RTEL1) antibody
  • regulator of telomere elongation helicase 1 (rtel1) antibody
  • RAD3-like DNA-binding helicase protein (AT1G79950) antibody
  • regulator of telomere elongation helicase 1 (LOC100286037) antibody
  • regulator of telomere elongation helicase 1 (Rtel1) antibody
  • AI451565 antibody
  • AW540478 antibody
  • bK3184A7.3 antibody
  • C20orf41 antibody
  • DKCB5 antibody
  • F18B13.3 antibody
  • F18B13_3 antibody
  • NHL antibody
  • RGD1306721 antibody
  • Rtel antibody
  • zgc:113114 antibody

Protein level used designations for RTEL1

regulator of telomere elongation helicase 1 , helicase-like protein NHL , regulator of telomere length , DEAH helicase , regulator of telomere length helicase 1

GENE ID SPECIES
419262 Gallus gallus
458415 Pan troglodytes
485976 Canis lupus familiaris
100540349 Meleagris gallopavo
100561075 Anolis carolinensis
844335 Arabidopsis thaliana
100286037 Zea mays
51750 Homo sapiens
269400 Mus musculus
362288 Rattus norvegicus
505721 Bos taurus
503732 Danio rerio
100171800 Pongo abelii
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