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Regulatory Factor X 5 (RFX5) ELISA Kits

A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS\; MIM 209920). Additionally we are shipping RFX5 Antibodies (95) and RFX5 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human RFX5 RFX5 5993 P48382
Anti-Mouse RFX5 RFX5 53970  
Anti-Rat RFX5 RFX5 310659  
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More ELISA Kits for RFX5 Interaction Partners

Human Regulatory Factor X 5 (RFX5) interaction partners

  1. Data show arginine methyltransferase PRMT6 (show PRMT6 ELISA Kits) methylates the AT-hook motif of regulatory factor RFX5 and downregulates HLA-DQ expression.

  2. these data have identified as novel pathway whereby SIRT1 (show SIRT1 ELISA Kits) maintains COL1A2 (show COL1A2 ELISA Kits) synthesis in SMCs by modulating RFX5 activity.

  3. RFXAP (show RFXAP ELISA Kits)(C) consists of two alpha-helices that form a V-shaped structure that packs within the RFX5(N)(2) staple.

  4. interaction at COL1A2 (show COL1A2 ELISA Kits) start site and transcription repression

  5. The mutation for the fifth Bbare lymphocyte syndrome complementation group was found in RFX5 and was mapped to one of the arginines in a DNA-binding surface of this protein. Its wild-type counterpart restored function.

  6. RFX5 binds to the collagen transcription start site and represses collagen gene expression

  7. The identification of nuclear import and export sites on RFX molecules provides potential targets to modulate MHC class II expression.

  8. results demonstrate that RFX1 (show RFX1 ELISA Kits) and RFX5 differentially interact with class I HDACs underlying the different pathways when repressing collagen synthesis

  9. PPARgamma (show PPARG ELISA Kits) is within the RFX5.CIITA (show CIITA ELISA Kits) complex as judged by co-immunoprecipitation and DNA affinity precipitation studies

  10. RFXAP (show RFXAP ELISA Kits) and RFXB (show RFXANK ELISA Kits) have roles in relieving autoinhibition of RFX5

Mouse (Murine) Regulatory Factor X 5 (RFX5) interaction partners

  1. TSA (show PRDX2 ELISA Kits) treatment enhances the association of CIITA (show CIITA ELISA Kits) with the transcription factor RFX5, which ameliorates the down-regulation of CIITA (show CIITA ELISA Kits) recruitment to target promoters by HDAC2 (show HDAC2 ELISA Kits).

RFX5 Antigen Profile

Antigen Summary

A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS\; MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX (Steimle et al., 1995). RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined.

Gene names and symbols associated with Regulatory Factor X 5 (RFX5) ELISA Kits

  • regulatory factor X, 5 (influences HLA class II expression) (RFX5) antibody
  • regulatory factor X, 5 (influences HLA class II expression) (Rfx5) antibody

Protein level used designations for Regulatory Factor X 5 (RFX5) ELISA Kits

DNA-binding protein RFX5 , regulatory factor X 5 , DNA-binding protein Rfx5 , regulatory factor X, 5 , regulator factor X 5

GENE ID SPECIES
5993 Homo sapiens
53970 Mus musculus
483197 Canis lupus familiaris
100328902 Oryctolagus cuniculus
310659 Rattus norvegicus
100517711 Sus scrofa
539884 Bos taurus
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