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anti-Relaxin/insulin-Like Family Peptide Receptor 1 (RXFP1) Antibodies

RXFP1 encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. Additionally we are shipping RXFP1 Kits (30) and RXFP1 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RXFP1 59350 Q9HBX9
RXFP1 381489 Q6R6I7
Anti-Rat RXFP1 RXFP1 295144 Q6R6I6
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Top anti-RXFP1 Antibodies at antibodies-online.com

Showing 10 out of 75 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, IHC (p) Immunohistochemistry of RXFP1 staining in Paraffin Section of healthy Human breast tissue from lactating patient. The section was incubated with AP23447SU (1/4000) overnight and detected using Peroxidase anti Peroxidase (PAP)-Avidin-Biotin-Complex (ABC) combination method. DAB was used as the chromogen. The section was counter-stained with haemalaun. A: AP23447SU recognizes the stromal cells within the glands. B: Preimmune serum at the same dilution. Scale bar = 50 µm Ivell Re et al. Reprod Biol Endocrinol 1:114 0.1 mL Log in to see 6 to 8 Days
$742.50
Details
Human Rabbit Un-conjugated WB RXFP1 Antibody (C-term) (ABIN1881770) western blot analysis in A375 cell line lysates (35 µg/lane). This demonstrates the RXFP1 antibody detected the RXFP1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged LGR7 is approximately 3ng/ml as a capture antibody. Western Blot detection against Immunogen (36.19 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemical staining of uterus endometrium using anti-LGR7 antibody ABIN122209 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged LGR7 is approximately 3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p) Anti-RXFP1 antibody  ABIN1049305 IHC staining of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated IHC (p) Anti-RXFP1 antibody IHC staining of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN957486 concentration 10 ug/ml. 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p) Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details

RXFP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Mouse (Murine)


Top referenced anti-RXFP1 Antibodies

  1. Human Monoclonal RXFP1 Primary Antibody for ELISA, WB - ABIN566200 : Kern, Bryant-Greenwood: Characterization of relaxin receptor (RXFP1) desensitization and internalization in primary human decidual cells and RXFP1-transfected HEK293 cells. in Endocrinology 2009 (PubMed)
    Show all 8 references for ABIN566200

  2. Human Polyclonal RXFP1 Primary Antibody for IF, IHC (p) - ABIN615660 : Ivell, Balvers, Pohnke, Telgmann, Bartsch, Milde-Langosch, Bamberger, Einspanier: Immunoexpression of the relaxin receptor LGR7 in breast and uterine tissues of humans and primates. in Reproductive biology and endocrinology : RB&E 2004 (PubMed)

  3. Human Polyclonal RXFP1 Primary Antibody for WB - ABIN1881770 : Halls, Cooper: Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, beta-arrestin 2, PDE4D3 complex. in The EMBO journal 2010 (PubMed)

More Antibodies against RXFP1 Interaction Partners

Zebrafish Relaxin/insulin-Like Family Peptide Receptor 1 (RXFP1) interaction partners

  1. The rxfp1 expression pattern in Danio rerio embryos is very similar to that reported in the adult mammalian brain, suggesting a pivotal role of this receptor in the neurophysiology processes already at very early developmental stages.

Human Relaxin/insulin-Like Family Peptide Receptor 1 (RXFP1) interaction partners

  1. The complex binding mode of the peptide hormone H2 relaxin to its receptor RXFP1 has been deciphered.

  2. RXFP1 gene expression was dysregulated in the anterior cingulate of bipolar patients.

  3. H2 relaxin amide is fully active at the relaxin receptor RXFP1 and thus dimerization is not required for biological activity.

  4. Synthetic covalently linked dimeric form of H2 relaxin retains native RXFP1 activity and has improved in vitro serum stability.

  5. Using cells stably expressing RXFP1, we found that relaxin regulation of PPARgamma activity requires accumulation of cAMP and subsequent activation of cAMP-dependent protein kinase (PKA).

  6. RXFP-1 receptors are present at the ligament, cartilage, and synovium of the TM joint, indicating that it is a potential target for relaxin. This suggests that circulating relaxin may impact joint stability.

  7. To create a tool to investigate the low-affinity interaction, a protein scaffold system displaying exoloops 1 and 2 from RXFP1 was designed.

  8. RXFP1, is a complex G-protein coupled receptor (GPCR (show TAS1R3 Antibodies))and has a rhodopsin (show RHO Antibodies)-like 7 transmembrane helix region and a large ecto (show TRIM33 Antibodies)-domain containing Leucine-rich repeats and a Low Desnsity Lipoprotein Class-A module at the N-terminus.

  9. We have developed and assessed four microRNA against human RXFP1.

  10. The development of a quantitative high-throughput platform for an RXFP1 agonist screen.

Mouse (Murine) Relaxin/insulin-Like Family Peptide Receptor 1 (RXFP1) interaction partners

  1. No differences were found in RXFP1 expression related to aging.

  2. Colonic tissue expresses RXFP1 in smooth muscle cells of the muscular wall and in neurons of the myenteric plexus.

  3. relaxin/RXFP1 signaling in smooth muscle cells is important for normal collagen turnover and relaxation of the pubic symphysis during pregnancy

  4. Rxfp1, Rxfp2 (show RXFP2 Antibodies), and Nr3c1 (show NR3C1 Antibodies) mRNAs were expressed on the developing maxilla and mandible, Meckel's cartilage, tongue, and tooth primordia between mouse embryonic days 13.5-18.5.

  5. maternal exposure to simazine causes disturbed relaxin signaling pathway and testicular dysfunction

  6. H3 relaxin exerts antifibrotic actions via RXFP1 receptor

  7. The downregulation of RXFP1 resulted in significant decrease in metastasis rate in PC3 (show BTG2 Antibodies) tumors.

  8. Rxfp1 acts in an autocrine and/or paracrine fashion upstream of PCDHY (show PCDH11Y Antibodies) in regulating increased canonical Wnt (show WNT2 Antibodies) signaling in prostate cancer.

  9. neither Insl3 (show INSL3 Antibodies) nor Lgr8 (show RXFP2 Antibodies) contribute to the RLN (show RLN1 Antibodies) signaling pathway; Insl3 (show INSL3 Antibodies)/Lgr8 (show RXFP2 Antibodies) and Rln1 (show RLN1 Antibodies)/Lgr7 actions do not overlap in vivo

  10. mouse and rat LGR7 are the relaxin receptors in these species

Pig (Porcine) Relaxin/insulin-Like Family Peptide Receptor 1 (RXFP1) interaction partners

  1. RXFP1 and RXFP2 (show RXFP2 Antibodies) signal intensities were mostly located in the plasma membrane region in oocytes and embryonic cells. Spermatozoa displayed stronger RXFP2 (show RXFP2 Antibodies) signal than RXFP1

  2. This study provides evidence for expression of RLN-RXFP1 ligand-receptor system in the boar testis, suggesting that the testes act as a source and possible target tissue of RLN.

RXFP1 Antigen Profile

Protein Summary

This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a role in endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with RXFP1

  • relaxin/insulin-like family peptide receptor 1 (RXFP1) antibody
  • relaxin/insulin-like family peptide receptor 1 (LOC100222591) antibody
  • relaxin/insulin-like family peptide receptor 1 (rxfp1) antibody
  • relaxin/insulin-like family peptide receptor 1 (Rxfp1) antibody
  • relaxin/insulin-like family peptide receptor 1 (LOC100345713) antibody
  • Gm1018 antibody
  • Lgr7 antibody
  • RXFP2 antibody
  • RXFPR1 antibody

Protein level used designations for RXFP1

leucine-rich repeat-containing G protein-coupled receptor 7 , relaxin/insulin-like family peptide receptor 1 , relaxin receptor 1-like , relaxin receptor 1 , leucine-rich repeat-containing 7 , leucine-rich repeat-containing G-protein coupled receptor 7 , relaxin family peptide receptor 1 , relaxin/insulin-like family peptide receptor 2

GENE ID SPECIES
461572 Pan troglodytes
701107 Macaca mulatta
100222591 Taeniopygia guttata
100483514 Ailuropoda melanoleuca
100494807 Xenopus (Silurana) tropicalis
100498669 Danio rerio
100548436 Meleagris gallopavo
100562228 Anolis carolinensis
100591035 Nomascus leucogenys
59350 Homo sapiens
381489 Mus musculus
295144 Rattus norvegicus
100345713 Oryctolagus cuniculus
100721183 Cavia porcellus
100127453 Sus scrofa
475479 Canis lupus familiaris
532277 Bos taurus
422415 Gallus gallus
101107224 Ovis aries
Selected quality suppliers for anti-RXFP1 (RXFP1) Antibodies
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