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anti-Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2) Antibodies

RXFP2 encodes a member of the GPCR (G protein-coupled, 7-transmembrane receptor) family. Additionally we are shipping RXFP2 Proteins (5) and RXFP2 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RXFP2 122042 Q8WXD0
RXFP2 140498 Q91ZZ5
RXFP2 363866  
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Top anti-RXFP2 Antibodies at antibodies-online.com

Showing 10 out of 65 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from Jurkat cells, using RXFP2 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, IHC (p) Immunohistochemistry of RXFP2 staining in Paraffin Section of Human testis. The section was incubated with AP23449SU (1/4000) overnight and detected using ABC stainig Kit. DAB was used as the chromogen. The section was counter-stained with haemalaun. A: AP23449SU recognizes interstitial Leydig cells and germ cells (arrow heads). B: Preimmune serum at the same dilution. Scale bar = 50 µm Anand-Ivell R et al. Biol Reprod 74:945-953. 0.1 mL Log in to see 6 to 8 Days
$742.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemical staining of Uterus using anti- RXFP2 antibody ABIN122210 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-RXFP2 antibody  ABIN1049309 IHC staining of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemical staining of Uterus using anti- RXFP2 antibody ABIN122211 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB RXFP2 Antibody (C-term)  western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the RXFP2 antibody detected the RXFP2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p) Anti-RXFP2 antibody  ABIN1049310 IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details

RXFP2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,


, , , , , , , , ,
Mouse (Murine) ,


Rat (Rattus)


Top referenced anti-RXFP2 Antibodies

  1. Human Polyclonal RXFP2 Primary Antibody for ELISA, WB - ABIN1535993 : Hsu, Nakabayashi, Nishi, Kumagai, Kudo, Sherwood, Hsueh: Activation of orphan receptors by the hormone relaxin. in Science (New York, N.Y.) 2002 (PubMed)

  2. Human Polyclonal RXFP2 Primary Antibody for IF, IHC (p) - ABIN615664 : Anand-Ivell, Relan, Balvers, Coiffec-Dorval, Fritsch, Bathgate, Ivell: Expression of the insulin-like peptide 3 (INSL3) hormone-receptor (LGR8) system in the testis. in Biology of reproduction 2006 (PubMed)

More Antibodies against RXFP2 Interaction Partners

Human Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2) interaction partners

  1. Mapping key regions of the RXFP2 low-density lipoprotein class-A module that are involved in signal activation.

  2. Findings suggest a novel and gender-specific role for INSL3 (show INSL3 Antibodies) and cognate receptor RXFP2 signaling in ocular surface homeostasis.

  3. These results provide new mechanistic insights into the binding and activation events of RXFP1 (show RXFP1 Antibodies) and RXFP2 by their native hormone ligands.

  4. Identification of key residues essential for the structural fold and receptor selectivity within the A-chain of human gene-2 (H2) relaxin

  5. relaxin-2 (show RLN1 Antibodies) and its receptors RXFP1 (show RXFP1 Antibodies) and RXFP2 are expressed in GSV and their expression is significantly decreased in varicose GSV

  6. haplotype analysis of the RXFP2 gene in T222P carriers and their parents showed that this variant is linked to the previously inferred C-C-G-A-13 haplotype and consequently provides further support to the 'founder effect' hypothesis

  7. higher expression of LGR8 may facilitate tumor invasiveness in the early clinical stage of hepatocellular carcinoma.

  8. Data show that synthetic parallel dimer of the B-chain of INSL3 (show INSL3 Antibodies) is a potent inhibitor of the native peptide's binding to its receptor, RXFP2.

  9. the only clinical consequence of alterations of the INSL3 (show INSL3 Antibodies)-LGR8 system seems to be failure of the testis to normally descend in the scrotum during embryonic development, without affecting the spermatogenic and endocrine components of the testis itself

  10. mutations involving the human LGR8 gene do not represent a frequent cause of cryptorchidism in the Finnish population

Mouse (Murine) Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2) interaction partners

  1. data suggest a novel role for Rln (show RLN1 Antibodies) in craniofacial skeletal development and metabolism through Rxfp2

  2. Rxfp1 (show RXFP1 Antibodies), Rxfp2, and Nr3c1 (show NR3C1 Antibodies) mRNAs were expressed on the developing maxilla and mandible, Meckel's cartilage, tongue, and tooth primordia between mouse embryonic days 13.5-18.5.

  3. Spermatogonial stem cells undergo drastic depletion in the cryptorchid testes of RXFP2 deficient mice.

  4. Data suggest that Insl3 (show INSL3 Antibodies)/Rxfp2 (insulin-like peptide 3 (show INSL3 Antibodies)/relaxin receptor 2) signaling is important for testicular descent; however, germ-cell deletion of Rxfp2 did not affect spermatogenesis, germ cell survival, or male fertility.

  5. Prenatal exposure to diethylstilbestrol increased the expression of LGR8 mRNA in the mouse gubernaculum testis.

  6. A deficiency for Rxfp2 on Cav1 (show CAV1 Antibodies)-deficient background led to more than a 2-fold increase in the incidence of uterine cysts.

  7. A mouse model was created containing a novel missense mutation in Relaxin/insulin-like family peptide receptor 2 which likely prevents binding to its ligand, Insulin-like peptide 3 (show INSL3 Antibodies), resulting in failure of the transabdominal phase of testicular descent.

  8. RXFP2 signaling pathway plays an important role in mediating androgen action to stimulate gubernaculum development during inguinoscrotal testis descent.

  9. Insulin-like 3 (show INSL3 Antibodies) peptide or great cause cryptorchidism (undescended testes) in mice.

  10. Disruption of the Greatgene causes failure of the transabdominal phase of descent, identical to that seen in the Insl3 (show INSL3 Antibodies)-deficient mutants, consistent with the recent data suggesting that Great gene encodes the Insl3 (show INSL3 Antibodies) transmembrane receptor.

RXFP2 Antigen Profile

Protein Summary

This gene encodes a member of the GPCR (G protein-coupled, 7-transmembrane receptor) family. Mutations in this gene are associated with cryptorchidism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RXFP2

  • relaxin/insulin-like family peptide receptor 2 (RXFP2) antibody
  • relaxin/insulin-like family peptide receptor 2 (Rxfp2) antibody
  • Gpcr antibody
  • Gpr106 antibody
  • Great antibody
  • INSL3R antibody
  • Lgr8 antibody
  • LGR8.1 antibody
  • RXFPR2 antibody

Protein level used designations for RXFP2

G protein coupled receptor affecting testicular descent , G-protein coupled receptor 106 , G-protein coupled receptor affecting testicular descent , leucine-rich repeat-containing G protein-coupled receptor 8 , leucine-rich repeat-containing G-protein coupled receptor 8 , relaxin family peptide receptor 2 , relaxin receptor 2 , G protein-coupled receptor 106 , INSL3 receptor

GENE ID SPECIES
122042 Homo sapiens
140498 Mus musculus
363866 Rattus norvegicus
450220 Canis lupus familiaris
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