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Renalase is a flavin adenine dinucleotide-dependent amine oxidase that is secreted into the blood from the kidney (Xu et al., 2005 [PubMed 15841207]).[supplied by OMIM, Mar 2008].. Additionally we are shipping Renalase, FAD-Dependent Amine Oxidase Antibodies (93) and Renalase, FAD-Dependent Amine Oxidase Kits (26) and many more products for this protein.
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Human RNLS Protein expressed in Wheat germ - ABIN1347031
Du, Huang, Huang, Yang, Gao, Wang, Huang, Li, Wang, Zhang, Wang, Cheng, Tong, Qin, Huang, Wang: Renalase is a novel target gene of hypoxia-inducible factor-1 in protection against cardiac ischaemia-reperfusion injury. in Cardiovascular research 2015
High RNLS expression is associated with melanoma.
Renalase gene rs2296545 polymorphism is significantly associated with increased risk of hypertension(HT), whereas rs2576178 polymorphism may not be associated with the susceptibility to HT
The rs10887800 renalase gene polymorphism significantly increased the risk of coronary artery disease in hemodialyzed end-stage renal disease patients.
genetic association studies in a population of pregnant women in Pakistan: Data suggest that an SNP in renalase (rs10887800; but not rs2576178) is modestly associated with gestational diabetes mellitus in the population studied; no difference was observed in the serum levels of renalase in this case-control study.
analysis of metabolic function of renalase
Lack of the N-terminal peptide, the structural precondition for FAD (show BRCA2 Proteins) binding, suggests that extracellular (circulating) renalase acts in a FAD (show BRCA2 Proteins)-independent manner and mechanisms of its action are not associated with FAD (show BRCA2 Proteins).
Findings of the present study suggest that blood pressure may be increased by GG genotype and G allele of rs10887800 renalase polymorphism and the polymorphism may increase the susceptibility to preeclampsia.
plasma renalase was not significantly associated with hypertension and high brachial-ankle pulse wave velocity
Data show that nhibition of renalase caused tumor cell apoptosis and cell cycle arrest.
marked increase of glomerular renalase and its association with macrophages suggest that it might play an important role in disease progression of LN
revealed renalase as a novel target gene of HIF-1alpha (show HIF1A Proteins) in protection against myocardial ischaemia/reperfusion injury
Renalase promotes cell survival and protects against renal injury in mice through the activation of intracellular signaling cascades, independent of its ability to metabolize catecholamines.
Renalase is wildly expressed in kidney, including glomeruli, tubule, mesangial cells, podocytes and tubule epithelial cells, and may be secreted by tubule epithelial cells primarily
the identification of a renalase homologue from mouse, termed mMAO-C (mouse monoamine oxidase-C) after the monoamine oxidase-A (show MAOA Proteins) and -B (MAO-A (show MAOA Proteins) and -B
Renalase is a flavin adenine dinucleotide-dependent amine oxidase that is secreted into the blood from the kidney (Xu et al., 2005
chromosome 10 open reading frame 59
, monoamine oxidase-C