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The protein encoded by RMND1 belongs to the evolutionary conserved sif2 family of proteins that share the DUF155 domain in common. Additionally we are shipping Required For Meiotic Nuclear Division 1 Homolog (S. Cerevisiae) Antibodies (5) and many more products for this protein.
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Expression of ESR1 (show ESR1 Proteins), RMND1 and CCDC170 (show CCDC170 Proteins) associated with variants in separate enhancer elements predisposing breast cancer. [meta-analysis]
Results demonstrate that the RMND1 complex is necessary for mitochondrial translation, possibly by coordinating the assembly or maintenance of the mitochondrial ribosome.
The RMND1 mutation caused haploinsufficiency that was rescued by overexpression of the wild-type transcript in mutant fibroblasts; this overexpression increased the levels and activities of mitochondrial respiratory-chain proteins.
The protein encoded by this gene belongs to the evolutionary conserved sif2 family of proteins that share the DUF155 domain in common. This protein is thought to be localized in the mitochondria and involved in mitochondrial translation. Mutations in this gene are associated with combined oxidative phosphorylation deficiency-11. Alternatively spliced transcript variants have been found for this gene.
required for meiotic nuclear division 1 homolog (S. cerevisiae)
, required for meiotic nuclear division protein 1 homolog
, required for meiotic nuclear division protein 1 homolog-like
, implantation-associated gene-1