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Resistance To Inhibitors of Cholinesterase 3 Homolog (C. Elegans) (RIC3) ELISA Kits

The protein encoded by RIC3 promotes functional expression of homomeric nicotinic acetylcholine receptors at the cell surface. Additionally we are shipping RIC3 Antibodies (27) and RIC3 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse RIC3 RIC3 320360 Q8BPM6
Anti-Human RIC3 RIC3 79608 Q7Z5B4
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More ELISA Kits for RIC3 Interaction Partners

Mouse (Murine) Resistance To Inhibitors of Cholinesterase 3 Homolog (C. Elegans) (RIC3) interaction partners

  1. In neurons, Ric-3 ER retention appears to promote transport within the dendritic ER subcompartment, thereby restricting 7 trafficking to dendrites and preventing axonal transport.

Human Resistance To Inhibitors of Cholinesterase 3 Homolog (C. Elegans) (RIC3) interaction partners

  1. expression of chaperones such as Ric-3 can influence proteins associating with alpha7-nAChRs

  2. RIC-3 differentially regulates assembly and expression of different nicotinic receptor subunits. These results also show that nicotine-mediated upregulation of alpha4beta2 receptors can be dynamically regulated by the presence of the chaperone, RIC-3.

  3. RIC-3 gene rs1528133 variation was not found to be effective over any analyzed obesity related parameter, but associated with higher glycemic load, protein and fat eating behavior and antihypertensive drug use

  4. Xenopus laevis RIC-3 is more effective than either the homomeric human or C. elegans protein in chaperoning the expression of nematode nicotinic receptor ACR (show ACR ELISA Kits)-16 in Xenopus oocytes.

  5. RIC-3 exclusively enhances the surface expression of human homomeric 5-hydroxytryptamine type 3A (5-HT3A (show HTR3A ELISA Kits)) receptors despite direct interactions with 5-HT3A (show HTR3A ELISA Kits), -C, -D, and -E subunits.

  6. ric-3 appears to be necessary for proper folding and/or assembly of alpha7 receptors in HEK293 cells

  7. RIC-3 may play a role in 5-HT (show DDC ELISA Kits)(3A) receptor folding, assembly, or transport to the cell surface

  8. hRIC-3 can act as a specific regulator of alpha7 and 5-HT3 (show HTR3A ELISA Kits) expression at different levels by increasing the number of mature receptors and facilitating its transport to the membrane

  9. Mutations in the ric-3 gene affect maturation of nicotinic acetylcholine receptors.

  10. both isoforms of RIC-3 play a role in determining 5-HT3 receptor (show HTR3A ELISA Kits) composition.

RIC3 Antigen Profile

Antigen Summary

The protein encoded by this gene promotes functional expression of homomeric nicotinic acetylcholine receptors at the cell surface. It enhances currents generated by these receptors by expediting receptor transport to the cell surface and by increasing receptor number. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RIC3

  • resistance to inhibitors of cholinesterase 3 homolog (C. elegans) (Ric3) antibody
  • RIC3 acetylcholine receptor chaperone (RIC3) antibody
  • AYST720 antibody
  • E130307J04Rik antibody
  • PRO1385 antibody

Protein level used designations for RIC3

protein RIC-3 , resistant to inhibitor of cholinesterase 3 , resistance to inhibitors of cholinesterase 3 homolog

GENE ID SPECIES
320360 Mus musculus
79608 Homo sapiens
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