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Resistance To Inhibitors of Cholinesterase 3 Homolog (C. Elegans) Proteins (RIC3)

The protein encoded by RIC3 promotes functional expression of homomeric nicotinic acetylcholine receptors at the cell surface. Additionally we are shipping RIC3 Antibodies (27) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RIC3 320360 Q8BPM6
RIC3 79608 Q7Z5B4
RIC3    
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Top RIC3 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,684.00
Details

RIC3 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , ,
, ,
Xenopus tropicalis

More Proteins for Resistance To Inhibitors of Cholinesterase 3 Homolog (C. Elegans) (RIC3) Interaction Partners

Mouse (Murine) Resistance To Inhibitors of Cholinesterase 3 Homolog (C. Elegans) (RIC3) interaction partners

  1. In neurons, Ric-3 ER retention appears to promote transport within the dendritic ER subcompartment, thereby restricting 7 trafficking to dendrites and preventing axonal transport.

Human Resistance To Inhibitors of Cholinesterase 3 Homolog (C. Elegans) (RIC3) interaction partners

  1. expression of chaperones such as Ric-3 can influence proteins associating with alpha7-nAChRs

  2. RIC-3 differentially regulates assembly and expression of different nicotinic receptor subunits. These results also show that nicotine-mediated upregulation of alpha4beta2 receptors can be dynamically regulated by the presence of the chaperone, RIC-3.

  3. RIC-3 gene rs1528133 variation was not found to be effective over any analyzed obesity related parameter, but associated with higher glycemic load, protein and fat eating behavior and antihypertensive drug use

  4. Xenopus laevis RIC-3 is more effective than either the homomeric human or C. elegans protein in chaperoning the expression of nematode nicotinic receptor ACR (show ACR Proteins)-16 in Xenopus oocytes.

  5. RIC-3 exclusively enhances the surface expression of human homomeric 5-hydroxytryptamine type 3A (5-HT3A (show HTR3A Proteins)) receptors despite direct interactions with 5-HT3A (show HTR3A Proteins), -C, -D, and -E subunits.

  6. ric-3 appears to be necessary for proper folding and/or assembly of alpha7 receptors in HEK293 cells

  7. RIC-3 may play a role in 5-HT (show DDC Proteins)(3A) receptor folding, assembly, or transport to the cell surface

  8. hRIC-3 can act as a specific regulator of alpha7 and 5-HT3 (show HTR3A Proteins) expression at different levels by increasing the number of mature receptors and facilitating its transport to the membrane

  9. Mutations in the ric-3 gene affect maturation of nicotinic acetylcholine receptors.

  10. both isoforms of RIC-3 play a role in determining 5-HT3 receptor (show HTR3A Proteins) composition.

RIC3 Protein Profile

Protein Summary

The protein encoded by this gene promotes functional expression of homomeric nicotinic acetylcholine receptors at the cell surface. It enhances currents generated by these receptors by expediting receptor transport to the cell surface and by increasing receptor number. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RIC3

  • resistance to inhibitors of cholinesterase 3 homolog (C. elegans) (Ric3)
  • RIC3 acetylcholine receptor chaperone (RIC3)
  • AYST720 protein
  • E130307J04Rik protein
  • PRO1385 protein

Protein level used designations for RIC3

protein RIC-3 , resistant to inhibitor of cholinesterase 3 , resistance to inhibitors of cholinesterase 3 homolog

GENE ID SPECIES
320360 Mus musculus
79608 Homo sapiens
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