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Retinal Degeneration 3 Proteins (RD3)

RD3 encodes a retinal protein that is associated with promyelocytic leukemia-gene product (PML) bodies in the nucleus. Additionally we are shipping RD3 Antibodies (3) and RD3 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RD3 343035 Q7Z3Z2
RD3 74023 Q8BRE0
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Top RD3 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

RD3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

More Proteins for Retinal Degeneration 3 (RD3) Interaction Partners

Human Retinal Degeneration 3 (RD3) interaction partners

  1. This study reports the results of an international study aimed at delineating the clinical and molecular spectrum of RD3 mutations in retinal dystrophies.

  2. Mutations in RD3 are a very rare cause of Leber's congenital amaurosis (LCA (show CLTA Proteins)) associated with an extremely severe form of retinal dystrophy (show MERTK Proteins).

  3. RD3 suppresses the basal catalytic activity of guanylyl cyclase activating proteins (GCAP (show ALPPL2 Proteins)) in a noncompetitive manner.

  4. Identification and sequence analysis of C1orf36.

  5. the retinopathy-associated RD3 protein is part of subnuclear protein complexes involved in diverse processes, such as transcription and splicing.

Mouse (Murine) Retinal Degeneration 3 (RD3) interaction partners

  1. Direct association between RD3 and GCAP1 is important for GC1 targeting.

  2. Studies indicate that RD3 plays an essential role in the exit of guanylate cyclase from the endoplasmic reticulum and its trafficking to photoreceptor outer segments.

  3. Changes in gene expression associated with photoreceptor degeneration in the rd3 mouse model of Leber congenital amaurosis (LCA (show CLTA Proteins)) type 12, are characterized.

  4. photoreceptor degeneration in the rd3 mouse, rcd2 dog, and LCA12 patients is caused by impaired RD3-mediated guanylate cyclase expression and trafficking

  5. Rd3 is preferentially expressed in the retina and exhibits increasing expression through early postnatal development.

RD3 Protein Profile

Protein Summary

This gene encodes a retinal protein that is associated with promyelocytic leukemia-gene product (PML) bodies in the nucleus. Mutations in this gene cause Leber congenital amaurosis type 12, a disease that results in retinal degeneration. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with Retinal Degeneration 3 Proteins (RD3)

  • retinal degeneration 3 (RD3)
  • retinal degeneration 3 (Rd3)
  • 3322402L07Rik protein
  • C1orf36 protein
  • LCA12 protein
  • rd-3 protein
  • rd3 protein

Protein level used designations for Retinal Degeneration 3 Proteins (RD3)

protein RD3 , retinal degeneration protein 3

GENE ID SPECIES
343035 Homo sapiens
74023 Mus musculus
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