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Retinal G Protein Coupled Receptor Proteins (RGR)

RGR encodes a putative retinal G-protein coupled receptor. Additionally we are shipping RGR Antibodies (53) and RGR Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RGR 57811 Q9Z2B3
RGR 5995 P47804
Rat RGR RGR 306307  
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Top RGR Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 9 Days
$491.43
Details

RGR Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Retinal G Protein Coupled Receptor (RGR) Interaction Partners

Mouse (Murine) Retinal G Protein Coupled Receptor (RGR) interaction partners

  1. structure of rhodopsin and opsin dimer in native membranes

  2. The role of Rgr using rgr-/- single and rdh5 (show RDH5 Proteins)-/-rgr-/- double knockout mice under a number of light conditions was studied; results suggest that RGR and RDH5 (show RDH5 Proteins) are likely to function in the retinoid cycle, although their role is not essential

  3. RGR-opsin mediates light-dependent translocation of all-trans-retinyl esters from a storage pool in lipid droplets to an "isomerase pool" in membranes of the endoplasmic reticulum.

Human Retinal G Protein Coupled Receptor (RGR) interaction partners

  1. conclude that the ability of hRgr to activate both Ral and Ras is responsible for its transformation-inducing phenotype and it could be an important contributor in the development of some T-cell malignancies

  2. It is likely that mutations in RGR, RBP3 (show E2F1 Proteins), and possibly RBP1 occur rarely in inherited retinal dystrophies.

  3. E150K opsin is partially colocalized with the cis/medial Golgi compartment but not with the trans-Golgi network; results are consistent with recessive pattern of inheritance; retinal degeneration results from deficient export of opsin from the Golgi

  4. These results indicate that after exon-skipping RGR splice isoform (RGR-d) is synthesized, the RGR-d epitope is released at the basal surface of the retinal pigment epithelium and deposited into Bruch's membrane in human eyes throughout adult life.

  5. RGR-opsin mediates light-dependent translocation of all-trans-retinyl esters from a storage pool in lipid droplets to an "isomerase pool" in membranes of the endoplasmic reticulum.

  6. the exon-skipping variant of RGR (RGR-d) is found in extracellular deposits;at the base of early-stage drusen mounds in the older donors and may precede the formation of these drusen

RGR Protein Profile

Protein Summary

This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with RGR

  • retinal G protein coupled receptor (RGR)
  • retinal G protein coupled receptor (rgr)
  • retinal G protein coupled receptor a (rgra)
  • retinal G protein coupled receptor (Rgr)
  • MGC84794 protein
  • rgr protein
  • RP44 protein
  • zgc:110660 protein

Protein level used designations for RGR

RPE-retinal G protein-coupled receptor , retinal g-protein receptor opsin , rgr opsin , retinal G protein coupled receptor , retinal G-protein coupled receptor , RGR opsin , RGR-opsin , RPE retinal G-protein coupled receptor

GENE ID SPECIES
423619 Gallus gallus
444753 Xenopus laevis
450906 Pan troglodytes
489072 Canis lupus familiaris
548767 Xenopus (Silurana) tropicalis
550575 Danio rerio
57811 Mus musculus
5995 Homo sapiens
306307 Rattus norvegicus
280911 Bos taurus
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