You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Retinitis Pigmentosa 1 (Autosomal Dominant) (RP1) Antibodies

RP1 encodes a member of the doublecortin family.

list all antibodies Gene Name GeneID UniProt
RP1 6101 P56715
RP1 681377  
RP1 19888 P56716
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-RP1 Antibodies at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Reactivity Host Conjugate Application Quantity Supplier Delivery Price Details
Human Rabbit Alexa Fluor 350 IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit FITC IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 594 IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Cy5 IF (p) 100 μL Log in to see 14 to 21 Days
$379.50
Details
Human Rabbit Cy3 IF (p) 100 μL Log in to see 14 to 21 Days
$379.50
Details
Human Rabbit Cy5.5 IF (p) 100 μL Log in to see 14 to 21 Days
$379.50
Details

RP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,


, , , , , , , , , , ,
Rat (Rattus) ,


, , , , , , , , , , ,
Mouse (Murine) ,


, , , , , , , , , , ,

More Antibodies against RP1 Interaction Partners

Human Retinitis Pigmentosa 1 (Autosomal Dominant) (RP1) interaction partners

  1. The L66P mutation in the first doublecortin (show DCX Antibodies) domain of the Rp1 (show STK19 Antibodies) gene impairs Rp1 (show STK19 Antibodies) protein localization and function, leading to abnormalities in photoreceptor outer segment structure and progressive photoreceptor degeneration.

  2. We suggest that arRP patients with high myopic refractive error should be preferentially analysed for RP1 (show STK19 Antibodies) mutations.

  3. it reports that different regions of RP1 (show STK19 Antibodies) can also lead to arRCD.

  4. Two novel heterozygous null mutations in RP1 (show STK19 Antibodies) co-segregate with the disease in autosomal recessive retinitis pigmentosa patients.

  5. RP1 (show STK19 Antibodies) phosphorylation at Ser (show SIGLEC1 Antibodies)(236) by CK2 (show CSNK2A1 Antibodies) seems to play a significant role in cell adhesion and might initiate new insights in the CK2 (show CSNK2A1 Antibodies) and EB1 (show MAPRE2 Antibodies) family protein association.

  6. Data found pathogenic DNA variants in the genes RP1 (show STK19 Antibodies), USH2A (show USH2A Antibodies), CNGB3 (show CNGB3 Antibodies), NMNAT1 (show NMNAT1 Antibodies), CHM (show CHM Antibodies), and ABCA4 (show ABCA4 Antibodies), responsible for retinitis pigmentosa, Usher syndrome, achromatopsia, Leber congenital amaurosis, choroideremia (show CHM Antibodies), or recessive Stargardt/cone-rod dystrophy cases.

  7. The most severe missense mutation occurred in patients with p.D984G in RP1 (show STK19 Antibodies).

  8. A novel homozygous retinitis pigmentosa nonsense mutation in exon 4 of the RP1 (show STK19 Antibodies) gene, c.1012C>T (p.R338*) was identified in the proband and her two affected sisters.

  9. molecular mechanism of RP1 (show STK19 Antibodies) mutation

  10. The distribution of these novel and previously reported RP1 (show STK19 Antibodies) mutations makes it challenging to describe a unifying mutational mechanism for dominant versus recessive RP1 (show STK19 Antibodies)-related retinitis pigmentosa.

Mouse (Murine) Retinitis Pigmentosa 1 (Autosomal Dominant) (RP1) interaction partners

  1. The L66P mutation in the first doublecortin (show DCX Antibodies) domain of the Rp1 gene impairs Rp1 protein localization and function, leading to abnormalities in photoreceptor outer segment structure and progressive photoreceptor degeneration.

  2. RP1 is required for the correct orientation and higher order stacking of outer segment discs.

  3. RP1 is a photoreceptor-specific microtubule-associated protein (show SPAG5 Antibodies) that participates in controlling the length and stability of the photoreceptor axoneme.

  4. The disruption of Rp1 changed gene expression in the c-Jun N-terminal kinase signaling cascades.

  5. Rp1 and Rp1L1 play essential and synergistic roles in affecting photosensitivity and morphogenesis of rod photoreceptors. Our findings suggest that mutations in RP1L1 could underlie retinopathy or modify RP1 disease expression

RP1 Antigen Profile

Protein Summary

This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains, which bind microtubules and regulate microtubule polymerization. The encoded protein is a photoreceptor microtubule-associated protein and is required for correct stacking of outer segment disc. This protein and the RP1L1 protein, another retinal-specific protein, play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. Because of its response to in vivo retinal oxygen levels, this protein was initially named ORP1 (oxygen-regulated protein-1). This protein was subsequently designated RP1 (retinitis pigmentosa 1) when it was found that mutations in this gene cause autosomal dominant retinitis pigmentosa. Mutations in this gene also cause autosomal recessive retinitis pigmentosa. Two transcript variants encoding distinct isoforms are resulted from alternative promoters and alternative splicing.

Gene names and symbols associated with RP1

  • retinitis pigmentosa 1 (autosomal dominant) (rp1) antibody
  • retinitis pigmentosa 1 (autosomal dominant) (RP1) antibody
  • retinitis pigmentosa 1 (human) (Rp1) antibody
  • Dcdc3 antibody
  • DCDC4A antibody
  • mG145 antibody
  • MGC83581 antibody
  • Orp1 antibody
  • Rp1h antibody

Protein level used designations for RP1

retinitis pigmentosa 1 (autosomal dominant) , retinitis pigmentosa RP1 protein , oxygen-regulated protein 1-like , oxygen-regulated protein 1 , retinitis pigmentosa 1 protein , retinitis pigmentosa RP1 protein homolog , retinitis pigmentosa 1 homolog

GENE ID SPECIES
447052 Xenopus laevis
472766 Pan troglodytes
677695 Macaca mulatta
100053179 Equus caballus
100188920 Xenopus (Silurana) tropicalis
100355685 Oryctolagus cuniculus
100444488 Pongo abelii
6101 Homo sapiens
280916 Bos taurus
403565 Canis lupus familiaris
681377 Rattus norvegicus
19888 Mus musculus
Selected quality suppliers for anti-RP1 (RP1) Antibodies
Did you look for something else?