You are viewing an incomplete version of our website. Please click to reload the website as full version.

Retinitis Pigmentosa GTPase Regulator Interacting Protein 1 Proteins (RPGRIP1)

RPGRIP1 encodes a photoreceptor protein that interacts with retinitis pigmentosa GTPase regulator protein and is a key component of cone and rod photoreceptor cells. Additionally we are shipping Retinitis Pigmentosa GTPase Regulator Interacting Protein 1 Antibodies (28) and Retinitis Pigmentosa GTPase Regulator Interacting Protein 1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RPGRIP1 57096 Q96KN7
RPGRIP1 77945 Q9EPQ2
Rat RPGRIP1 RPGRIP1 305850  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Retinitis Pigmentosa GTPase Regulator Interacting Protein 1 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

RPGRIP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Retinitis Pigmentosa GTPase Regulator Interacting Protein 1 (RPGRIP1) Interaction Partners

Human Retinitis Pigmentosa GTPase Regulator Interacting Protein 1 (RPGRIP1) interaction partners

  1. RPGRIP1 has an essential role in the photoreceptor connecting cilia, and photoreceptors lacking RPGRIP1 are unable to maintain the light sensing outer segments. [review]

  2. SPATA7 (show SPATA7 Proteins) plays a role in RPGRIP1-mediated protein trafficking across the connecting cilium of photoreceptor cells. Apoptotic degeneration of these cells triggered by protein mislocalization is a mechanism of disease progression in LCA3 (show SPATA7 Proteins)/juvenile RP patients

  3. Although the present patients did not show sufficient clinical findings as Leber congenital amaurosis (LCA (show CLTA Proteins)), PCR findings and direct sequencing following microarray analysis confirmed that they were LCA (show CLTA Proteins).

  4. Neurodevelopmental delay is a potential feature of strictly defined LCA, documented in our series for some children with homozygous RPGRIP1 and GUCY2D mutations.

  5. We report a novel RPGRIP1 mutation causing LCA (show CLTA Proteins) in a consanguineous Emirati family. To the best of our knowledge, this alteration has not been described in the literature so far.

  6. Recessive RPGRIP1 mutations cause a severe cone-rod Leber congenital amaurosis phenotype, often with poor or no fixation and an oculodigital sign. In the first decade of life retinal changes are clinically most evident in the periphery.

  7. RPGRIP1 in human and in canine model involves protein network and photoreceptor cilia.

  8. Nek4 interaction with both RPGRIP1 and the RPGRIP1L is involved in cilium assembly.

  9. heterozygous non-synonymous variants of RPGRIP1 may cause or increase the susceptibility to various forms of glaucoma

  10. Studies highlight the recent developments in understanding the mechanism of cilia-dependent photoreceptor degeneration due to mutations in RPGR (show RPGR Proteins) and PGR (show PGR Proteins)-interacting proteins in severe genetic diseases.

Mouse (Murine) Retinitis Pigmentosa GTPase Regulator Interacting Protein 1 (RPGRIP1) interaction partners

  1. RPGRIP1 has an essential role in the photoreceptor connecting cilia, and photoreceptors lacking RPGRIP1 are unable to maintain the light sensing outer segments. [review]

  2. RPGRIP1 loss in photoreceptors shifts the subcellular partitioning of SDCCAG8 (show SDCCAG8 Proteins) and NPHP4 (show NPHP4 Proteins) to the membrane fraction associated to the endoplasmic reticulum.

  3. RPGRIP1 is essential for rod photoreceptor outer segment morphogenesis.

  4. RPGRIP1 and nephrocystin-4 (show NPHP4 Proteins) interact strongly in vitro and in vivo, and that they colocalize in the retina

Cow (Bovine) Retinitis Pigmentosa GTPase Regulator Interacting Protein 1 (RPGRIP1) interaction partners

  1. RPGR (show RPGR Proteins) and RPGRIP isoforms are distributed and co-localized at restricted foci throughout the outer segments of human and bovine, but not mice rod photoreceptors.

  2. RPGRIP1 and nephrocystin-4 (show NPHP4 Proteins) interact strongly in vitro and in vivo, and that they colocalize in the retina

Retinitis Pigmentosa GTPase Regulator Interacting Protein 1 (RPGRIP1) Protein Profile

Protein Summary

This gene encodes a photoreceptor protein that interacts with retinitis pigmentosa GTPase regulator protein and is a key component of cone and rod photoreceptor cells. Mutations in this gene lead to autosomal recessive congenital blindness.

Gene names and symbols associated with RPGRIP1

  • retinitis pigmentosa GTPase regulator interacting protein 1 (RPGRIP1)
  • retinitis pigmentosa GTPase regulator interacting protein 1 (Rpgrip1)
  • 0610005A07Rik protein
  • 4930401L23Rik protein
  • 4930505G06Rik protein
  • A930002K18Rik protein
  • AA415034 protein
  • CORD13 protein
  • LCA6 protein
  • nmf247 protein
  • RGI1 protein
  • RGRIP protein
  • RPGRIP protein
  • RPGRIP1d protein

Protein level used designations for RPGRIP1

retinitis pigmentosa GTPase regulator interacting protein 1 , X-linked retinitis pigmentosa GTPase regulator-interacting protein 1-like , x-linked retinitis pigmentosa GTPase regulator-interacting protein 1-like , RPGR-interacting protein 1 , X-linked retinitis pigmentosa GTPase regulator-interacting protein 1

GENE ID SPECIES
473331 Pan troglodytes
475400 Canis lupus familiaris
100029857 Monodelphis domestica
100072725 Equus caballus
100357598 Oryctolagus cuniculus
100405160 Callithrix jacchus
100441722 Pongo abelii
100467875 Ailuropoda melanoleuca
57096 Homo sapiens
77945 Mus musculus
305850 Rattus norvegicus
282656 Bos taurus
Selected quality suppliers for Retinitis Pigmentosa GTPase Regulator Interacting Protein 1 Proteins (RPGRIP1)
Did you look for something else?