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Retinoblastoma Binding Protein 5 (RBBP5) ELISA Kits

RBBP5 encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. Additionally we are shipping Retinoblastoma Binding Protein 5 Antibodies (56) and Retinoblastoma Binding Protein 5 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human RBBP5 RBBP5 5929 Q15291
Anti-Mouse RBBP5 RBBP5 213464 Q8BX09
Anti-Rat RBBP5 RBBP5 304794  
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More ELISA Kits for Retinoblastoma Binding Protein 5 Interaction Partners

Human Retinoblastoma Binding Protein 5 (RBBP5) interaction partners

  1. This study demonstrated that RBQ3 might play an important role in glioma, and RBQ3 inhibitors might be novel anti-tumor agents.

  2. The identified components revealed factors involved in histone methylation and cell cycle control and include Ash2L, RbBP5, WDR5, HCF-1, DBC-1, and EMSY.

  3. Non active site mutations in the MLL1 SET domain render the protein defective for H3K4 dimethylation by the MLL1 core complex, which is associated with a loss of the ability of MLL1 to interact with WRAD or with the RbBP5/Ash2L heterodimer.

  4. Data indicate that MLL1 methylates Ash2L in the absence of histone H3 (show HIST3H3 ELISA Kits), but only when assembled within a complex with WDR5 (show WDR5 ELISA Kits) and RbBP5.

  5. structural and biochemical analyses reveal a basic surface on Ash2L as the RbBP5-binding interface, and this interface is crucial for both RbBP5 binding and MLL1 methyltransferase activity regulation

  6. Results show that Depletion of CHD8 (show CHD8 ELISA Kits) enhances HOXA2 (show HOXA2 ELISA Kits) expression and a loss of the WDR5 (show WDR5 ELISA Kits)/Ash2L/RbBP5 subcomplex.

  7. analysis of menin's role as a tumor suppressor and binding sites of Rbbp5 and MLL1

Mouse (Murine) Retinoblastoma Binding Protein 5 (RBBP5) interaction partners

  1. a phosphorylation switch on RbBP5 stimulates WRAD complex formation and significantly increases KMT2 (lysine [K] methyltransferase 2 (show DNMT1 ELISA Kits)) enzyme methylation rates

  2. Characterization of a novel WDR5 (show WDR5 ELISA Kits)-binding site that recruits RbBP5 through a conserved motif to enhance methylation of histone H3 (show HIST3H3 ELISA Kits) lysine 4 by mixed lineage leukemia protein-1.

Retinoblastoma Binding Protein 5 (RBBP5) Antigen Profile

Antigen Summary

This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Gene names and symbols associated with RBBP5

  • retinoblastoma binding protein 5 (RBBP5) antibody
  • retinoblastoma binding protein 5 (rbbp5) antibody
  • retinoblastoma binding protein 5 (LOC100356995) antibody
  • retinoblastoma binding protein 5 (Rbbp5) antibody
  • 4933411J24Rik antibody
  • C330016J05 antibody
  • DKFZp469C191 antibody
  • MGC56078 antibody
  • MGC80141 antibody
  • MGC97793 antibody
  • RBBP5 antibody
  • RBQ3 antibody
  • SWD1 antibody
  • zgc:56078 antibody
  • zgc:85864 antibody

Protein level used designations for RBBP5

retinoblastoma binding protein 5 , retinoblastoma-binding protein 5-like , RBBP-5 , SWD1, Set1c WD40 repeat protein, homolog , retinoblastoma-binding protein 5 , retinoblastoma-binding protein RBQ-3

GENE ID SPECIES
100054708 Equus caballus
393215 Danio rerio
446510 Xenopus laevis
457665 Pan troglodytes
595072 Xenopus (Silurana) tropicalis
100173341 Pongo abelii
100356995 Oryctolagus cuniculus
100470847 Ailuropoda melanoleuca
100513301 Sus scrofa
100544888 Meleagris gallopavo
100566805 Anolis carolinensis
100597470 Nomascus leucogenys
5929 Homo sapiens
488568 Canis lupus familiaris
510455 Bos taurus
213464 Mus musculus
304794 Rattus norvegicus
419826 Gallus gallus
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