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Retinoblastoma Binding Protein 7 Proteins (RBBP7)

This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. Additionally we are shipping Retinoblastoma Binding Protein 7 Antibodies (85) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RBBP7 5931 Q16576
RBBP7 245688 Q60973
Rat RBBP7 RBBP7 83712 Q71UF4
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Top Retinoblastoma Binding Protein 7 Proteins at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Candida albicans His tag   1 mg Log in to see 56 to 66 Days
$3,050.67
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Yeast Encephalitozoon cuniculi His tag   1 mg Log in to see 56 to 66 Days
$3,058.00
Details
Yeast Yeast His tag   1 mg Log in to see 56 to 66 Days
$3,111.17
Details
Yeast Candida His tag   1 mg Log in to see 56 to 66 Days
$3,166.17
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$3,182.67
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,182.67
Details

RBBP7 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Retinoblastoma Binding Protein 7 (RBBP7) Interaction Partners

Zebrafish Retinoblastoma Binding Protein 7 (RBBP7) interaction partners

  1. Rbb4l acts as an enhancer of Nodal/Smad2/3 signaling during embryogene-sis, and depends on the existence of Nodal signaling

  2. CAF-1 (show CNOT7 Proteins) activity is essential for differentiation in several organs, including the retina, optic tectum, pectoral fins, and head skeleton

Human Retinoblastoma Binding Protein 7 (RBBP7) interaction partners

  1. the CRL4 complex containing RBBP7 (CRL4(RBBP7)) might regulate mitosis by promoting ubiquitin-dependent loading of newly synthesized CENP-A (show CENPA Proteins) during the G1 phase of the cell cycle.

  2. Ras induced RbAp46 expression increases invasion of bladder cancer cells.

  3. Both of RbAp46 mRNA and protein levels were upregulated significantly in NSCLC cancer tissues. Serum levels of RbAp46 were markedly higher in NSCLC patients than in healthy controls.

  4. RbAp46 expression suppresses the transformed phenotypes of breast cancer cells, and dysregulation of RbAp46 expression may contribute to breast cancer tumorigenesis.

  5. RbAp46 inhibits cell growth and suppresses the transformed phenotypes of tumor cell lines.

  6. RT-PCR data show high expression of putative tumor suppressor genes Rsk4 (show RPS6KA6 Proteins) and RbAp46 in 47% and 79% of breast carcinoma cases, respectively, whereas Cldn2 (show CLDN2 Proteins) was down-regulated in 52% of breast cancer cases compared with normal adjacent tissues.

  7. RbAp46 folds into a seven-bladed beta propeller structure and binds histone H4 in a groove formed between an N-terminal alpha helix and an extended loop inserted into blade six.

  8. Data show that RbAp46 and RbAp48 (show RBBP4 Proteins) interact with estrogen receptor (ER)alpha (show ESR1 Proteins) at endogenous, estrogen-responsive genes and alter expression of endogenous, ERalpha (show ESR1 Proteins)-activated and -repressed genes in MCF-7 breast cancer cells.

Mouse (Murine) Retinoblastoma Binding Protein 7 (RBBP7) interaction partners

  1. The results collectively suggest that Rbbp7 is a potentially functional player regulating normal histone acetylation modification and cyclin D3 (show CCND3 Proteins) expression in stromal cells during postimplantation decidual development.

  2. RBBP7 as a novel regulator of histone deacetylation during oocyte maturation and provide evidence that such deacetylation is required for proper chromosome segregation by regulating the localized chromosomal passenger complex function.

  3. PRC2 complex that includes mPINC and RbAp46 may provide the epigenetic modifications that maintain a progenitor population of mammary epithelial cells committed to an alveolar fate in the pregnant and involuted gland.

  4. Characterization of the gene encoding mouse retinoblastoma binding protein-7

Retinoblastoma Binding Protein 7 (RBBP7) Protein Profile

Protein Summary

This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RBBP7

  • retinoblastoma binding protein 7 (rbbp7)
  • retinoblastoma binding protein 7 (RBBP7)
  • retinoblastoma binding protein 7 (LOC100229904)
  • retinoblastoma binding protein 7 (LOC100352868)
  • retinoblastoma binding protein 4, like (rbb4l)
  • retinoblastoma binding protein 7 (Rbbp7)
  • WD40 repeat protein similar to S. cerevisiae HAT2 (YEL056W) histone acetyltransferase subunit 2 (HAT2)
  • AA409861 protein
  • AI173248 protein
  • AU019541 protein
  • BB114024 protein
  • Caf1 protein
  • DKFZp459K2224 protein
  • mRbAp46 protein
  • RbAp46 protein
  • RBBP-7 protein
  • rbbp7 protein
  • wu:fa13g08 protein
  • wu:fb50h10 protein
  • wu:fc29d09 protein
  • zgc:56477 protein
  • zgc:85617 protein

Protein level used designations for RBBP7

RBBP-7 , histone-binding protein RBBP7 , retinoblastoma-binding protein 7 , retinoblastoma binding protein 7 , histone-binding protein RBBP7-like , nucleosome-remodeling factor subunit RBAP46 , G1/S transition control protein-binding protein RbAp46 , histone acetyltransferase type B subunit 2 , retinoblastoma-binding protein RbAp46 , retinoblastoma-binding protein p46 , G1/S transition control protein-binding protein , Rbap46 polypeptide , potential histone acetyltransferase subunit

GENE ID SPECIES
394900 Xenopus (Silurana) tropicalis
480854 Canis lupus familiaris
713843 Macaca mulatta
100229904 Taeniopygia guttata
100302664 Pongo abelii
100352868 Oryctolagus cuniculus
100414385 Callithrix jacchus
100439948 Pongo abelii
100607103 Nomascus leucogenys
322129 Danio rerio
5931 Homo sapiens
245688 Mus musculus
83712 Rattus norvegicus
537402 Bos taurus
395390 Gallus gallus
380056 Xenopus laevis
3646093 Candida albicans SC5314
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