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Retinoic Acid Early Transcript 1E Proteins (RAET1E)

RAET1E belong to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. Additionally we are shipping Retinoic Acid Early Transcript 1E Antibodies (96) and Retinoic Acid Early Transcript 1E Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RAET1E 135250 Q8TD07
RAET1E 379043 Q9CZQ6
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Top Retinoic Acid Early Transcript 1E Proteins at antibodies-online.com

Showing 7 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$382.86
Details

RAET1E Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Mouse (Murine)

Top referenced Retinoic Acid Early Transcript 1E Proteins

  1. Human RAET1E Protein expressed in Escherichia coli (E. coli) - ABIN1098707 : Antoun, Jobson, Cook, OCallaghan, Moss, Briggs: Single nucleotide polymorphism analysis of the NKG2D ligand cluster on the long arm of chromosome 6: Extensive polymorphisms and evidence of diversity between human populations. in Human immunology 2010 (PubMed)
    Show all 2 references for ABIN1098707

More Proteins for Retinoic Acid Early Transcript 1E (RAET1E) Interaction Partners

Human Retinoic Acid Early Transcript 1E (RAET1E) interaction partners

  1. RAET1E promoter polymorphism has increased to nine types, and there are now 12 alleles determined by the coding exons, including one null.

  2. Patients whose tumors had high expression of RAET1E, ULBP1 and ULBP3 surviving a median of 11, 14 and 11 months, respectively, compared with disease-specific survival of 29, 30 and 25 months in patients whose tumors showed no expression of these ligands

  3. Binds the activating receptor NKG2D (show KLRK1 Proteins).

  4. immune escape mechanism of tumors via alternative splicing of ULBP RNA to generate a free soluble ULBP protein, RAET1E2, that may impair NKG2D (show KLRK1 Proteins)-mediated NK cell cytotoxicity to tumors

  5. All ULBP4 splice variants (ULBP4-I, ULBP4-II and ULBP4-III) were type 1 membrane-spanning molecules and had the ability to bind with human NKG2D (show KLRK1 Proteins) receptor in vitro

  6. data suggest that ULBP4 functions as a ligand for both TCRgammadelta and NKG2D (show KLRK1 Proteins) and may play a key role in immune surveillance of tumor development and clearance of viral infection

Mouse (Murine) Retinoic Acid Early Transcript 1E (RAET1E) interaction partners

  1. CD4 (show CD4 Proteins)(+) NKG2D (show KLRK1 Proteins)(+) T cells induce NKG2D (show KLRK1 Proteins) down-regulation in natural killer cells in CD86 (show CD86 Proteins)-RAE-1epsilon transgenic mice.

  2. Reveal Raet1e, a major histocompatibility complex class 1-like molecule expressed in lesional aortic endothelial cells and macrophage-rich regions, as a novel atherosclerosis gene.

  3. Raet1e genes are directly transcriptionally activated by E2F (show E2F1 Proteins) family transcription factors, which play a central role in regulating cell cycle entry.

  4. RAE1 (show RAE1 Proteins) expression was sufficient to induce the recruitment of adoptively transferred CTLs to islets.

Retinoic Acid Early Transcript 1E (RAET1E) Protein Profile

Protein Summary

This gene belong to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. This and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RAET1E

  • retinoic acid early transcript 1E (RAET1E)
  • retinoic acid early transcript 1E (Raet1e)
  • bA350J20.7 protein
  • LETAL protein
  • N2DL-4 protein
  • NKG2DL4 protein
  • RAET1E2 protein
  • RL-4 protein
  • ULBP4 protein

Protein level used designations for RAET1E

NKG2D ligand 4 , RAE-1-like transcript 4 , lymphocyte effector toxicity activation ligand , RAE-1-epsilon , RAE1epsilon , Rae-1 epsilon , retinoic acid early-inducible protein 1-epsilon

GENE ID SPECIES
135250 Homo sapiens
379043 Mus musculus
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