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RARRES2 encodes a secreted chemotactic protein that initiates chemotaxis via the ChemR23 G protein-coupled seven-transmembrane domain ligand. Additionally we are shipping RARRES2 Kits (44) and RARRES2 Proteins (30) and many more products for this protein.
Showing 10 out of 99 products:
Mouse (Murine) Polyclonal RARRES2 Primary Antibody for IF (cc), IF (p) - ABIN1715135
Krautbauer, Wanninger, Eisinger, Hader, Beck, Kopp, Schmid, Weiss, Dorn, Buechler: Chemerin is highly expressed in hepatocytes and is induced in non-alcoholic steatohepatitis liver. in Experimental and molecular pathology 2013
Show all 3 references for ABIN1715135
Mouse (Murine) Polyclonal RARRES2 Primary Antibody for IHC (p) - ABIN1701633
Gonzalvo-Feo, Del Prete, Pruenster, Salvi, Wang, Sironi, Bierschenk, Sperandio, Vecchi, Sozzani: Endothelial cell-derived chemerin promotes dendritic cell transmigration. in Journal of immunology (Baltimore, Md. : 1950) 2014
this study suggested that a role of STRA6 (show STRA6 Antibodies) polymorphism could also be of value in predicting the risk of type 2 diabetes mellitus(T2DM) while RARRES2 polymorphism could not predict the risk of T2DM.
Studied levels of salivary visfatin (show NAMPT Antibodies), chemerin, and progranulin (show GRN Antibodies) and in gingivitis, periodontitis, as well as healthy patients. Salivary progranulin (show GRN Antibodies) levels were similar in all groups; chemerin was detected at higher levels in the periodontitis group compared to the gingivitis and the healthy groups; visfatin (show NAMPT Antibodies) levels were higher in patients with gingivitis and periodontitis compared to those of healthy subjects.
Data show inverse Relationship of the CMKLR1 (show CMKLR1 Antibodies) Relative Expression and Chemerin Serum Levels in Obesity with Dysmetabolic Phenotype and Insulin (show INS Antibodies) Resistance
Oral lipid loading is linked to reduced circulating pro-inflammatory chemokines CCL2 (show CCL2 Antibodies), IP-10 (show CXCL10 Antibodies), and chemerin and to increased RANTES (show CCL5 Antibodies) levels, suggesting that dietary lipids affect immune function.
Metabolic syndrome in Egyptian females is associated with the minor allele of chemerin rs17173608 polymorphism.
Serum chemerin was significantly higher in the obese PCOS group compared with non-obese PCOS and the obese and non-obese control groups.
The synovial fluid and synovial membrane levels of chemerin are increased in knee osteoarthritis patients
Together, these findings suggest that CCL2 (show CCL2 Antibodies), RARRES2 and EFNB2 (show EFNB2 Antibodies) are host cell factors involved in respiratory syncytial virus replication.
serum chemerin may have a role in acute ischemic stroke and carotid artery plaque instability in Chinese populations
Suggest reduction of chemerin could contribute to the antiobesity/antidiabetic properties described for alpha-lipoic acid.
Study indicates that Chemerin plays a role in the negative cross-talk between skeletal muscle and adipose tissue. Specifically, Chemerin promotes the adipogenic differentiation potential and alters the myoblast cell fate from myogenesis to adipogenesis.
Data indicate that chemerin may play an important role in regulating mitochondrial remodelling and function in skeletal muscle.
The chemerin15 (C15) precursor, chemerin, and its receptor, ChemR23, are both upregulated after skin damage and the receptor is expressed by macrophages, neutrophils, and keratinocytes. C15 delivery dampens immediate inflammatory events.
findings reveal previously uncharacterized regulators of chemerin expression in skin and identify a physiologic role for chemerin in skin barrier defense against microbial pathogens.
A novel autocrine/paracrine role for chemerin in regulating osteoclast differentiation of hematopoietic stem cells
this study reports that retinoic acid-activated endothelial cells can promote myeloid and plasmacytoid dendritic cell transmigration across endothelial cell monolayers through the endogenous production of chemerin
Data suggest that chemerin/ChemR23 (chemokine-like receptor 1 (show CMKLR1 Antibodies)) signaling is not essential for adipocyte differentiation, but it appears to play a role in control of body weight and energy metabolism as overweight/obesity progresses.
Studies using isolated islets and perfused pancreas revealed impaired glucose-dependent insulin (show INS Antibodies) secretion (GSIS) in chemerin-deficient mice. Conversely, chemerin transgenic mice revealed enhanced GSIS and improved glucose tolerance.
Following TNFalpha (show TNF Antibodies) treatment, increased elastase and tryptase (show TPSAB1 Antibodies) modify the balance between activation and deactivation, elevating active chemerin concentration in adipocyte media and subsequent CMKLR1 (show CMKLR1 Antibodies) activation.
Chemerin regulates energy metabolism partly through the Akt (show AKT1 Antibodies) and ERK1/2 (show MAPK1/3 Antibodies) signaling pathways.
These results suggest that Chemerin promotes lipolysis in mature adipocytes and induces adipogenesis during preadipocyte re-differentiation, further indicating a dual role for Chemerin in the deposition of intramuscular fat in ruminant animals.
chemerin is a novel regulator of lactogenesis via its own receptor in bovine mammary epithelial cells
This gene encodes a secreted chemotactic protein that initiates chemotaxis via the ChemR23 G protein-coupled seven-transmembrane domain ligand. Expression of this gene is upregulated by the synthetic retinoid tazarotene and occurs in a wide variety of tissues. The active protein has several roles, including that as an adipokine, and is truncated on both termini from the proprotein.
RAR-responsive protein TIG2
, retinoic acid receptor responder protein 2
, tazarotene-induced gene 2 protein
, CHO functionally unknown type II transmembrane protein
, Tazarotene-induced gene 2 protein