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Retinol Binding Protein 3, Interstitial Proteins (RBP3)

Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. Additionally we are shipping Retinol Binding Protein 3, Interstitial Antibodies (56) and Retinol Binding Protein 3, Interstitial Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RBP3 19661 P49194
RBP3 24711  
RBP3 5949 P10745
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Top Retinol Binding Protein 3, Interstitial Proteins at antibodies-online.com

Showing 9 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$704.00
Details
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$774.40
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$563.20
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$889.07
Details
HOST_Escherichia coli (E. coli) Rat Un-conjugated   100 μg Log in to see 9 to 19 Days
$952.01
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

RBP3 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
,
Rat (Rattus)

Human , ,
,

More Proteins for Retinol Binding Protein 3, Interstitial (RBP3) Interaction Partners

Zebrafish Retinol Binding Protein 3, Interstitial (RBP3) interaction partners

  1. Our study, which provides the first structure of an IRBP with bound ligand, supports a potential role for fatty acids in regulating retinoid binding.

Mouse (Murine) Retinol Binding Protein 3, Interstitial (RBP3) interaction partners

  1. The 629-643 RBP-3 peptide is a major uveitogenic peptide for the induction of autoimmune uveoretinitis in C57BL/6J mice and the persistent clinical disease induced with one peptide leads to epitope spreading.

  2. We propose that down-regulation of IRBP may represent an early and novel pathogenic mechanism in degenerative retinal diseases

  3. Although death signaling proteins are increased, the caspase (show CASP3 Proteins)-dependent and independent apoptotic pathways are mildly activated in Irbp-deficient retinas.

  4. Secretory defect and cytotoxicity: the potential disease mechanisms for the retinitis pigmentosa (RP)-associated interphotoreceptor retinoid-binding protein (IRBP).

  5. In addition to its role in the visual cycle, IRBP is needed for normal eye development.

  6. IRBP is essential to normal cone function and demonstrate that differences exist in the visual cycle of rods and cones.

  7. these findings suggest that IRBP plays an important role in the delivery of 11-cis (show CISH Proteins)-retinol to cones and can facilitate cone function in the presence of light

  8. Tumor formation in mice with somatic inactivation of the retinoblastoma gene in interphotoreceptor retinol binding protein-expressing cells.

  9. analysis of the structure and sequence of the IRBP gene

  10. data show that presence of IRBP is necessary in ocular and pineal gland tissues for expression of autoimmune uveitis

Human Retinol Binding Protein 3, Interstitial (RBP3) interaction partners

  1. this report is the first to describe the retinal dystrophy (show MERTK Proteins) in children caused by homozygous nonsense RBP3 (show E2F1 Proteins) mutations, highlighting the requirement for IRBP (show GRB10 Proteins) in normal eye development and visual function.

  2. CMPK1 (show CMPK1 Proteins) and RBP3 (show E2F1 Proteins) are associated with corneal curvature in Asian populations.

  3. We found that most patients with macular telangiectasia-2 possess retinal autoantibodies, the most prevalent of which were directed against AGL (show AGL Proteins), RBP3 (show E2F1 Proteins), and CK-B.

  4. Secretory defect and cytotoxicity: the potential disease mechanisms for the retinitis pigmentosa (RP)-associated interphotoreceptor retinoid-binding protein (IRBP).

  5. It is likely that mutations in RGR (show RGR Proteins), RBP3 (show E2F1 Proteins), and possibly RBP1 occur rarely in inherited retinal dystrophies.

  6. Underproduction of IRBP (show GRB10 Proteins) is an early event in the human diabetic retina and is associated with retinal neurodegeneration.

  7. studies suggest that IRBP (show GRB10 Proteins) and S-Ag (show SAG Proteins) can initiate innate and, in sensitive individuals, adaptive immune response by attracting iDCs and T and B cells expressing CXCR3 (show CXCR3 Proteins) and CXCR5 (show CXCR5 Proteins)

  8. analysis of IRBP (show GRB10 Proteins) proteolysis is useful as a biomarker for uveitis

  9. Mutations in RBP3 (show E2F1 Proteins) are an infrequent cause of autosomal recessive retinitis pigmentosa.

  10. In interphotoreceptor retinoid-binding protein transgenic mice cone dysfunction appears to be caused by abnormal trafficking of cone opsins due to impaired delivery of all-transretinaldehyde chromophore without IRBP (show GRB10 Proteins).

Cow (Bovine) Retinol Binding Protein 3, Interstitial (RBP3) interaction partners

  1. IRBP is able to bind a variety of carotenoids at an affinity comparable to retinoids and with much stronger affinity than any fatty acid tested.

  2. In mouse immunization studies Ehrlichia canis amino acid sequence 44-59 is identified as a candidate mimicry epitope for interphotoreceptor retinoid-binding protein (IRBP) 201-216 and is capable of preventing ocular inflammation.

  3. KLF15 binds to multiple 9 bp consensus sites in the Rhodospin and IRBP promoters including the CRS-1 (show TWIST1 Proteins) and G-rich repressor elements.

Retinol Binding Protein 3, Interstitial (RBP3) Protein Profile

Protein Summary

Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process.The human IRBP gene is approximately 9.5 kbp in length and consists of four exons separated by three introns. The introns are 1.6-1.9 kbp long. The gene is transcribed by photoreceptor and retinoblastoma cells into an approximately 4.3-kilobase mRNA that is translated and processed into a glycosylated protein of 135,000 Da. The amino acid sequence of human IRBP can be divided into four contiguous homology domains with 33-38% identity, suggesting a series of gene duplication events. In the gene, the boundaries of these domains are not defined by exon-intron junctions, as might have been expected. The first three homology domains and part of the fourth are all encoded by the first large exon, which is 3,180 base pairs long. The remainder of the fourth domain is encoded in the last three exons, which are 191, 143, and approximately 740 base pairs long, respectively.

Gene names and symbols associated with RBP3

  • interphotoreceptor retinoid-binding protein (irbp)
  • retinol binding protein 3, interstitial (RBP3)
  • interphotoreceptor retinoid-binding protein (glr2547)
  • interphotoreceptor retinoid-binding protein (XOO2681)
  • interphotoreceptor retinoid-binding protein (AMED_0162)
  • interphotoreceptor retinoid-binding protein (ambt_08395)
  • retinol binding protein 3, interstitial (LOC100227987)
  • excision repair cross-complementing rodent repair deficiency, complementation group 6 (ERCC6)
  • retinol binding protein 3, interstitial (Rbp3)
  • D10S64 protein
  • D10S65 protein
  • D10S66 protein
  • IRBP protein
  • Rbp-3 protein
  • RBPI protein
  • RP66 protein

Protein level used designations for RBP3

irbp gene 2 , retinol-binding protein 3 , interphotoreceptor retinoid-binding protein , retinol binding protein 3, interstitial , retinol-binding protein 3-like , interstitial retinol-binding protein , interphotoreceptor retinoid binding protein , interphotoreceptor retinol- binding protein , 7S protein , IRBP , protein 7S

GENE ID SPECIES
30735 Danio rerio
395553 Gallus gallus
2600948 Gloeobacter violaceus PCC 7421
3261969 Xanthomonas oryzae pv. oryzae KACC 10331
9434373 Amycolatopsis mediterranei U32
10651281 Alteromonas sp. SN2
450440 Pan troglodytes
489084 Canis lupus familiaris
711582 Macaca mulatta
100018783 Monodelphis domestica
100227987 Taeniopygia guttata
100395148 Callithrix jacchus
100436295 Pongo abelii
100581780 Nomascus leucogenys
100155788 Sus scrofa
19661 Mus musculus
24711 Rattus norvegicus
5949 Homo sapiens
281443 Bos taurus
100723349 Cavia porcellus
101115179 Ovis aries
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