You are viewing an incomplete version of our website. Please click to reload the website as full version.

Retinol Dehydrogenase 5 (11-Cis/9-Cis) Proteins (RDH5)

RDH5 encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. Additionally we are shipping Retinol Dehydrogenase 5 (11-Cis/9-Cis) Antibodies (32) and Retinol Dehydrogenase 5 (11-Cis/9-Cis) Kits (15) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RDH5 19682  
RDH5 5959 Q92781
Rat RDH5 RDH5 366791  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Retinol Dehydrogenase 5 (11-Cis/9-Cis) Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,781.17
Details

RDH5 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Retinol Dehydrogenase 5 (11-Cis/9-Cis) (RDH5) Interaction Partners

Zebrafish Retinol Dehydrogenase 5 (11-Cis/9-Cis) (RDH5) interaction partners

  1. zRDHA and zRDHB show strong expression within the gut (show GUSB Proteins) of developing zebrafish embryos

  2. A role for G143 in zebrafish 17beta-HSD 1 and M146 and M147 in the two zebrafish paralogs prRDH 1 and prRDH 2, respectively, in substrate specificity.

Mouse (Murine) Retinol Dehydrogenase 5 (11-Cis/9-Cis) (RDH5) interaction partners

  1. The role of Rgr (show RGR Proteins) using rgr (show RGR Proteins)-/- single and rdh5-/-rgr (show RGR Proteins)-/- double knockout mice under a number of light conditions was studied; results suggest that RGR (show RGR Proteins) and RDH5 are likely to function in the retinoid cycle, although their role is not essential

  2. RDH11 (show RDH11 Proteins) has a measurable role in regenerating the visual pigment by complementing RDH5 in retinal pigment epithelium.

Human Retinol Dehydrogenase 5 (11-Cis/9-Cis) (RDH5) interaction partners

  1. A novel c.832C>T (p.Arg278Ter) nonsense mutation in RDH5 was identified. Preserved rod function was observed in one young subject in this study.

  2. RDH5 sequence analysis revealed a novel five base pair deletion, c.913_917delGTGCT (p.Val305Hisfs*29), in family A, and a novel missense mutation, c.758T>G (p.Met253Arg), in family B with fundus albipunctatus.

  3. Four novel RDH5 gene mutations were identified in fundus albipunctatus Israeli patients. Of them, the null mutations c.343C>T (p.R54X) and c. 242delTGCC were the most prevalent.

  4. The proband had a compound heterozygotic missense mutation of Cys59Ser (TGC (show TGM2 Proteins) --> AGC (show ACAN Proteins)) and a nonsense mutation of Trp95ter (TGG --> TGA (show TBX1 Proteins)) in the RDH5 gene.

  5. The clinical and electrophysiologic phenotype of patients with RDH5 retinopathy is variable.

  6. Mutations in RDH5 associated with fundus albipunctatus seem to prevent normal lipofuscin accumulation.

  7. Macular dystrophy is caused by the RDH5 mutation as a phenotype variation in fundus albipunctus.

  8. Macular dystrophy is caused by the RDH5 gene mutation as a phenotype variation in fundus albipunctatus.

  9. Fundus changes due to Fundus albipunctatus associated with mutations in the RDH5 gene.

  10. RDH5 gene mutations cause a progressive cone dystrophy or macular dystrophy as well as night blindness. The clinical phenotype including electrophysiological responses varied among patients with the RDH5 gene mutations.

Retinol Dehydrogenase 5 (11-Cis/9-Cis) (RDH5) Protein Profile

Protein Summary

This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene.

Gene names and symbols associated with RDH5

  • retinol dehydrogenase 1 (rdh1)
  • retinol dehydrogenase 5 (11-cis/9-cis) (rdh5)
  • retinol dehydrogenase 5 (11-cis/9-cis) (RDH5)
  • retinol dehydrogenase 5 (Rdh5)
  • retinol dehydrogenase 5 (11-cis/9-cis) (Rdh5)
  • 9-cis protein
  • 9cRDH protein
  • AI987873 protein
  • cRDH protein
  • HSD17B9 protein
  • im:6901729 protein
  • MGC84134 protein
  • RDH1 protein
  • RDH4 protein
  • RDH5 protein
  • RDHB protein
  • SDR9C5 protein
  • si:dkey-102c8.5 protein

Protein level used designations for RDH5

retinol dehydrogenase 2 , retinol dehydrogenase 5 (11-cis/9-cis) , 11-cis retinol dehydrogenase , 11-cis RDH , 11-cis RoDH , 9-cis retinol dehydrogenase , 9-cis-retinol dehydrogenase , cis-retinol dehydrogenase , retinol dehydrogenase type 5 , 9-cis-retinol specific dehydrogenase , retinol dehydrogenase 1 , retinol dehydrogenase 5 (11-cis and 9-cis) , short chain dehydrogenase/reductase family 9C, member 5 , P32

GENE ID SPECIES
378440 Danio rerio
444623 Xenopus laevis
467029 Pan troglodytes
481099 Canis lupus familiaris
496830 Xenopus (Silurana) tropicalis
556528 Danio rerio
709644 Macaca mulatta
100598708 Nomascus leucogenys
19682 Mus musculus
5959 Homo sapiens
281448 Bos taurus
366791 Rattus norvegicus
101115199 Ovis aries
Selected quality suppliers for Retinol Dehydrogenase 5 (11-Cis/9-Cis) Proteins (RDH5)
Did you look for something else?