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The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. Additionally we are shipping RHD Kits (4) and and many more products for this protein.
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The RHCE (show RHCE Antibodies) gene intron 4 of Han Chinese, Tibetans, and Mongols differs from the RHD gene intron 4 in the presence of a 652-bp fragment.
Reduced expression of D antigen is caused not only by missense mutation of the RHD gene, but also by silent mutation that may affect splicing.
Loss of heterozygosity of RhD gene on chromosome 1p in acute myeloid leukemia (show BCL11A Antibodies).
Rh antibodies in SCD (show SCD Antibodies) patients with RH variants can be clinically significant and, therefore, matching patients based on RH variants should be considered.
Paternal RHD zygosity determination in Tunisians: evaluation of three molecular tests.
Serologic findings of RhD alleles in Egyptians and their clinical implications.
An uneven distribution of RH variant alleles between Dogon and Fulani, in Mali. A high incidence of predicted partial-C phenotype encoded by RHCE (show RHCE Antibodies)*Ce-D(4)-ce was found in Fulani.
Despite the enormous diversity of RHD alleles, first-line weak D genotyping was remarkably informative, allowing for rapid classification of most samples with conspicuous RhD phenotype in Flanders, Belgium.
Splicing is altered in RHD*weak D Type 2 allele, a rare variant most commonly found in Caucasians; RHD including the full-length Exon 9 is transcribed in the presence of the c.1227G>A substitution frequently carried by Asians with DEL phenotype.
The frequency of D variants detected by IAT allele RHD(M295I) was 1:272 in D negative donors. Obviously, DEL phenotype is more common in some parts of European population than initially thought.
The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene.
D antigen (DCS)
, RH polypeptide 2
, Rh blood group antigen Evans
, Rh blood group, D anitgen
, Rhesus blood group D antigen allele DIII type 7
, Rhesus system D polypeptide
, blood group Rh(D) polypeptide
, rhesus D antigen
, Rh-like polypeptide
, Rhesus blood group CE and D
, erythrocyte membrane glycoprotein Rh30