Rhotekin (RTKN) ELISA Kits

RTKN encodes a scaffold protein that interacts with GTP-bound Rho proteins. Additionally we are shipping Rhotekin Antibodies (39) and Rhotekin Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human RTKN RTKN 6242 Q9BST9
Anti-Mouse RTKN RTKN 20166 Q8C6B2
Anti-Rat RTKN RTKN 297383 Q6V7V2
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More ELISA Kits for Rhotekin Interaction Partners

Human Rhotekin (RTKN) interaction partners

  1. Let-7a microRNA inhibits tumor cell growth and metastasis by directly targeting RTKN in human colon cancer.

  2. RTKN is upregulated in hepatocellular carcinoma.MicroRNA-152 inhibits tumor cell growth by directly targeting RTKN in hepatocellular carcinoma.

  3. The RTKN protein is associated with lung cancer in clinic samples and exerts anticancer activity in lung adenocarcinoma cells through inhibiting cell cycle progression and the DNA replication machinery.

  4. RTKN could affect the proliferation and metastasis of colon cancer by reducing expression of MCM2 (show MCM2 ELISA Kits)/3/5, CDK1 (show CDK1 ELISA Kits)/2 and PCNA (show PCNA ELISA Kits)

  5. suggest that interaction of S100A4 (show S100A4 ELISA Kits) and Rhotekin permits S100A4 (show S100A4 ELISA Kits) to complex with RhoA (show RHOA ELISA Kits) and switch Rho function from stress fiber formation to membrane ruffling to confer an invasive phenotypea

  6. Protein kinase D (show PRKD1 ELISA Kits) regulates RhoA (show RHOA ELISA Kits) activity via phosphorylation rhotekin at Ser (show SIGLEC1 ELISA Kits)-435.

  7. Rho/RTKN-mediated NF-kappaB (show NFKB1 ELISA Kits) activation leading to cell survival may play a key role in gastric tumorigenesis.

  8. These results suggest that the RTKN gene is involved in bladder carcinogenesis and progression in bladder carcinoma, indicating that RTKN gene could be a molecular target in cancer therapy.

  9. Lin-7B (show LIN7B ELISA Kits) is a binding partner for Rhotekin in the human brain cDNA library

  10. SEPT9 (show SEPT9 ELISA Kits) sequence alternations causing hereditary neuralgic amyotrophy are associated with altered interactions with SEPT4 (show SEPT4 ELISA Kits)/SEPT11 (show SEPT11 ELISA Kits) and resistance to Rho/Rhotekin-signaling

Mouse (Murine) Rhotekin (RTKN) interaction partners

  1. these findings suggest that cGK (show PRKG1 ELISA Kits)-Ialpha interacts with and phosphorylates rhotekin, thereby contributing to neurite outgrowth regulation.

Rhotekin (RTKN) Antigen Profile

Antigen Summary

This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with Rhotekin (RTKN) ELISA Kits

  • rhotekin (RTKN) antibody
  • rhotekin (rtkn) antibody
  • rhotekin (Rtkn) antibody
  • RTKN antibody

Protein level used designations for Rhotekin (RTKN) ELISA Kits

rhotekin , rhotekin-like

459334 Pan troglodytes
100053888 Equus caballus
100124981 Xenopus (Silurana) tropicalis
100349385 Oryctolagus cuniculus
100400941 Callithrix jacchus
100455723 Pongo abelii
100474465 Ailuropoda melanoleuca
100519086 Sus scrofa
6242 Homo sapiens
20166 Mus musculus
297383 Rattus norvegicus
475788 Canis lupus familiaris
539691 Bos taurus
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