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The protein encoded by RNASE4 belongs to the pancreatic ribonuclease family. Additionally we are shipping RNASE4 Antibodies (25) and RNASE4 Kits (1) and many more products for this protein.
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RNase 4 and RNase 5/ang (show ANG Proteins) 1 (show ANGPT1 Proteins) are unique among the RNase A (show RNASE1 Proteins) ribonuclease genes in that they maintain a complex gene locus that is conserved across species with transcription initiated from tissue-specific dual promoters followed by differential exon splicing.
Data show that the transcription of angiogenin (ANG (show ANG Proteins)) and ribonuclease 4 (RNASE4) promoter is influenced by RNA polymerase III (Pol III) elements and could be differentially regulated by an intragenic CCCTC binding factor (CTCF (show CTCF Proteins))-dependent chromatin loop.
RNASE4 (show ANG Proteins) not only stimulates the formation of neurofilaments from mouse embryonic cortical neurons, but also protects hypothermia-induced degeneration
The protein encoded by this gene belongs to the pancreatic ribonuclease family. It plays an important role in mRNA cleavage and has marked specificity towards the 3' side of uridine nucleotides. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes angiogenin share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region.
, ribonuclease 4
, RNase PL3
, ribonuclease PL3
, ribonuclease BL4