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RNASE7 is a member of the RNase A superfamily that has broad-spectrum antimicrobial activity and ribonuclease activity (Harder and Schroder, 2002 [PubMed 12244054]\\\\; Zhang et al., 2003 [PubMed 12527768]).[supplied by OMIM, Dec 2008].. Additionally we are shipping RNASE7 Antibodies (17) and RNASE7 Kits (12) and many more products for this protein.
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Insulin (show INS Proteins) and PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins) signaling are essential for RNase 7 expression and increased infection risks in diabetic patients may be secondary to suppressed RNase 7 production.
This article provides an overview about the role of RNase 7 in cutaneous defense with focus on the molecular mechanism of the antimicrobial activity of RNase 7, the regulation of RNase 7 expression, and the role of RNase 7 in skin diseases. [review]
RNH1 (show RNH1 Proteins) bound to RNase 7 and suppressed its antimicrobial activity by blocking its ability to bind the cell wall of uropathogenic bacteria.
epidermal growth factor (show EGF Proteins)-dependent RNase 7 and human beta-defensin-3 (show DEFB103A Proteins) expression upon infection with Trichophytum rubrum
RNase 7 is an antimicrobial protein that plays an important role in the innate immune defense system of human epithelia.
Suggest that RNase 7 may function as antimicrobial peptide (show cAMP Proteins) with a role in the differentiation and development of the primitive epidermis.
Levels of psoriasin (show S100A7 Proteins), RNase 7 and hBD-3 (show DEFB103A Proteins) expression - assessed by immunohistochemistry - varied between different body localisations.
the influence of STAT3 (show STAT3 Proteins) on the IL-17A (show IL17A Proteins)/IFN-gamma (show IFNG Proteins) -mediated RNase 7 induction
RNase 7 expression is increased in the urinary tract with infection and has antibacterial activity against uropathogens at micromolar concentrations.
a complex relationship between tear induction of miR (show MLXIP Proteins)-762, its modulation of innate defense genes, and P. aeruginosa internalization
RNASE7 is a member of the RNase A superfamily that has broad-spectrum antimicrobial activity and ribonuclease activity (Harder and Schroder, 2002
, ribonuclease 7
, skin-derived antimicrobial protein 2