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anti-Ribonuclease H2, Subunit B (RNASEH2B) Antibodies

RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. Additionally we are shipping Ribonuclease H2, Subunit B Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RNASEH2B 79621 Q5TBB1
RNASEH2B 67153 Q80ZV0
RNASEH2B 361056 Q5XI96
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Top anti-Ribonuclease H2, Subunit B Antibodies at antibodies-online.com

Showing 10 out of 23 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of RNASEH2B Antibody (Center) (ABIN650970) in CEM cell line lysates (35 µg/lane). RNASEH2B (arrow) was detected using the purified polyclonal antibody. RNASEH2B Antibody (Center) (ABIN650970) IHC analysis in formalin fixed and paraffin embedded human lymph tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit APC IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 9 to 11 Days
$313.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details
Human Rabbit FITC IHC, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit APC IHC, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit PE IHC, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit HRP IHC, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details

RNASEH2B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,


, , , , ,
Mouse (Murine)


Rat (Rattus)


More Antibodies against Ribonuclease H2, Subunit B Interaction Partners

Human Ribonuclease H2, Subunit B (RNASEH2B) interaction partners

  1. Aicardi-Goutieres syndrome 2 is caused by mutations in the ribonuclease H2 subunit B gene RNASEH2B.

  2. RNase H2 complex is assembled in the cytosol and imported into the nucleus in an RNase H2B-dependent manner.

  3. A genome-wide search for homozygosity in Aicardi-Goutieres syndrome patients in the Faroe Islands revealed one single 15.6 Mb region of homozygosity on chromosome 13, which included RNASEH2B, where a splice site mutation c.322-3C>G was identified.

  4. This study demonistrated that ribonuclease H2 mutation releated to Aicardi-Goutieres syndrome.

  5. Congenital infection is seen with preserved neurological function, most frequently due to RNASEH2B mutations.

  6. Examination of the effect of several Aicardi-Goutieres Syndrome-related mutations in the B subunit of RNase H2.

Mouse (Murine) Ribonuclease H2, Subunit B (RNASEH2B) interaction partners

  1. Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response

  2. Recent evidence gathered from ribonuclease H2 knock-out mice provides insight into the molecular mechanisms underlying Aicardi-Goutieres syndrome development and a potential role of DNA damage as a trigger of autoimmunity is discussed. [review]

  3. Study performed targeted mutagenesis of the mouse Rnaseh2b gene to gain insight into the in vivo role of the mammalian RNase H2 enzyme. Ablation of Rnaseh2b in mice leads to early embryonic lethality due to elevated DNA damage and reduced cellular proliferation during gastrulation.

  4. Data show that the interwoven architecture of RNase H2B and RNase H2C (show RNASEH2C Antibodies) that interface with RNase H2A (show RNASEH2A Antibodies) in a complex ideally suited for nucleic acid binding and hydrolysis coupled to protein-protein interaction motifs.

Ribonuclease H2, Subunit B (RNASEH2B) Antigen Profile

Protein Summary

RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2).

Gene names and symbols associated with RNASEH2B

  • ribonuclease H2, subunit B (RNASEH2B) antibody
  • ribonuclease H2, subunit B (Rnaseh2b) antibody
  • ribonuclease H2, subunit B (rnaseh2b) antibody
  • 1110019N06Rik antibody
  • 2610207P08Rik antibody
  • AGS2 antibody
  • Dleu8 antibody

Protein level used designations for RNASEH2B

Aicardi-Goutieres syndrome 2 protein , RNase H2 subunit B , deleted in lymphocytic leukemia 8 , ribonuclease H2 subunit B , ribonuclease HI subunit B , deleted in lymphocytic leukemia 8 homolog

GENE ID SPECIES
79621 Homo sapiens
67153 Mus musculus
361056 Rattus norvegicus
509258 Bos taurus
496343 Xenopus laevis
Selected quality suppliers for anti-Ribonuclease H2, Subunit B (RNASEH2B) Antibodies
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