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Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). Additionally we are shipping RNH1 Antibodies (120) and RNH1 Kits (27) and many more products for this protein.
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Human RNH1 Protein expressed in Wheat germ - ABIN1318405
Rucksaken, Pairojkul, Pinlaor, Khuntikeo, Roytrakul, Selmi, Pinlaor: Plasma autoantibodies against heat shock protein 70, enolase 1 and ribonuclease/angiogenin inhibitor 1 as potential biomarkers for cholangiocarcinoma. in PLoS ONE 2014
a novel mechanism of ANG (show ANG Proteins) in regulating PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins)/mTOR (show FRAP1 Proteins) signaling pathway via RI, is reported.
RNH1 bound to RNase 7 (show RNASE7 Proteins) and suppressed its antimicrobial activity by blocking its ability to bind the cell wall of uropathogenic bacteria.
angiogenin (show ANG Proteins) and ILK (show ILK Proteins) signaling pathway plays a pivotal role in mediating the inhibitory effects of RI on melanoma cells growth
RI could play a novel role in inhibiting metastasis of bladder cancer through regulating EMT (show ITK Proteins) and ILK (show ILK Proteins) signaling pathways.
RNH1 as a regulator of HDACi resistance in gastric cancer
RI might play a novel role in the development of bladder cancer through regulating EMT (show ITK Proteins) and the ILK (show ILK Proteins) signaling pathway.
PTEN-mediated miR (show MLXIP Proteins)-21 regulation is achieved by inhibiting the interaction between the Drosha (show DROSHA Proteins) complex and RNH1, revealing previously unidentified role of PTEN in the oncogenic miR (show MLXIP Proteins)-21 biogenesis
the anti-tumor effect of RNH1 is also involved in suppressing growth and metastasis
RNH1 (as a recombinant fusion protein) is localized to mitochondria, nuclei, and cytosol in HeLa and HCT cells; RNH1 appears to bind to various mitochondrial proteins.
Human ribonuclease inhibitor gene has antiangiogenic and antitumor effects when expressed in hematopoietic cells in mouse melanoma models.
X-ray crystallographic analysis of RNH1 from mouse, bovine and chicken binding to RNase reveals two residues that appear to contribute to the differential binding affinity.
Mouse angiogenin (show ANG Proteins) inhibitor 1 (show PPP1R1A Proteins) interacts with hylA of Streptococcus suis.
Cow placenta ribonuclease inhibitor (CPRI) was isolated, characterized and proved to have radical scavenging activities toward different reactive oxygen species.
Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988
, ribonuclease/angiogenin inhibitor 1
, placental RNase inhibitor
, placental ribonuclease inhibitor
, RNase inhibitor