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Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Additionally we are shipping RPL7 Proteins (11) and RPL7 Kits (9) and many more products for this protein.
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Human Polyclonal RPL7 Primary Antibody for EIA, WB - ABIN954601
Chou, Tai, Kirby, Lee, Lin: Importin β3 mediates the nuclear import of human ribosomal protein L7 through its interaction with the multifaceted basic clusters of L7. in FEBS letters 2010
Show all 5 references for ABIN954601
In case of L7, importin (show KPNA4 Antibodies) beta2 or importin (show KPNA4 Antibodies) beta3 are preferentially used by clusters with a high import efficiency.
RPL7 gene expression is decreased in follicular variant of papillary thyroid carcinoma.
importin (show KPNA4 Antibodies) beta3 is essential for the nuclear import of RPL7. The import is mediated via the multifaceted basic amino acid clusters present in the NH(2)-region of RPL7, and is RanGTP-dependent
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ribosomal proteins. It contains an N-terminal basic region-leucine zipper (BZIP)-like domain and the RNP consensus submotif RNP2. In vitro the BZIP-like domain mediates homodimerization and stable binding to DNA and RNA, with a preference for 28S rRNA and mRNA. The protein can inhibit cell-free translation of mRNAs, suggesting that it plays a regulatory role in the translation apparatus. It is located in the cytoplasm. The protein has been shown to be an autoantigen in patients with systemic autoimmune diseases, such as systemic lupus erythematosus. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
, ribosomal protein L7
, 60S ribosomal protein L7