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Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Additionally we are shipping RPS6 Kits (22) and RPS6 Proteins (20) and many more products for this protein.
Showing 10 out of 303 products:
Human Polyclonal RPS6 Primary Antibody for IF, WB - ABIN196982
McBride, Nemer: The C-terminal domain of c-fos is required for activation of an AP-1 site specific for jun-fos heterodimers. in Molecular and cellular biology 1998
Show all 4 references for ABIN196982
Human Polyclonal RPS6 Primary Antibody for EIA, IHC (p) - ABIN357338
Lott, Mackie: Isolation and characterization of cloned cDNAs that code for human ribosomal protein S6. in Gene 1988
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Human Polyclonal RPS6 Primary Antibody for WB - ABIN1881764
Glover, Oates, Tang, Moore, Tarnopolsky, Phillips: Resistance exercise decreases eIF2Bepsilon phosphorylation and potentiates the feeding-induced stimulation of p70S6K1 and rpS6 in young men. in American journal of physiology. Regulatory, integrative and comparative physiology 2008
Show all 4 references for ABIN1881764
Human Polyclonal RPS6 Primary Antibody for IF, IHC (p) - ABIN197470
Williams, Werner-Fraczek, Chang, Bailey-Serres: Regulated phosphorylation of 40S ribosomal protein S6 in root tips of maize. in Plant physiology 2003
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Human Polyclonal RPS6 Primary Antibody for EIA, FACS - ABIN954620
Fujita, Ito, Nakano, Kinoshita, Wate, Kusaka: Immunohistochemical identification of messenger RNA-related proteins in basophilic inclusions of adult-onset atypical motor neuron disease. in Acta neuropathologica 2008
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Human Polyclonal RPS6 Primary Antibody for ICC, IF - ABIN4350514
Castañeda, Genzor, van der Heijden, Sarkeshik, Yates, Ingolia, Bortvin: Reduced pachytene piRNAs and translation underlie spermiogenic arrest in Maelstrom mutant mice. in The EMBO journal 2014
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Data suggest ribosomal protein S6 (rpS6) as tumor marker for renal cell carcinoma (show MOK Antibodies).
Hyperphosphorylation of ribosomal protein S6 predicts unfavorable clinical survival in non-small cell lung cancer
p-rpS6 is a robust post-treatment indicator of HER2 (show ERBB2 Antibodies) pathway-targeted therapy resistance
Resistance to Selumetinib (AZD6244) in colorectal cancer cell lines is mediated by p70S6K (show RPS6KB1 Antibodies) and RPS6 activation.
Tanshinone IIA inhibits HIF-1alpha (show HIF1A Antibodies) and VEGF (show VEGFA Antibodies) expression in breast cancer cells via mTOR (show FRAP1 Antibodies)/p70S6K (show RPS6KB1 Antibodies)/RPS6/4E-BP1 (show EIF4EBP1 Antibodies) signaling pathway.
The expression levels of phospho-mTOR (show FRAP1 Antibodies) and phospho-S6RP may be potential predictive biomarkers for efficacy of everolimus in patients with metastatic renal cell carcinoma (show MOK Antibodies).
we report that phosphorylation of ribosomal protein S6 is greatly increased in BRCA1 deficient cells resistant to PARP (show COL11A2 Antibodies) inhibition
High Ribosomal Protein S6 is associated with renal cell carcinoma (show MOK Antibodies) metastases.
a novel mechanism for modulating the RPS6 function by PP1 (show PPA1 Antibodies) and ATM (show ATM Antibodies) which regulates cell growth and survival in response to DNA-damage stim
Downregulation of HELZ (show HELZ Antibodies) reduced translational initiation, resulting in the disassembly of polysomes, in a reduction of cell proliferation and hypophosphorylation of ribosomal protein S6.
in adult cardiac myocytes 4-hydroxy-trans-2-nonenal stimulates protein synthesis by activation of mTORC1-p70S6K (show RPS6KB1 Antibodies)-RPS6 signaling
rpS6 phosphorylation facilitates the increase in cyclin D1 (show CCND1 Antibodies) and decrease in cyclin E1 (show CCNE1 Antibodies) that underlie the hypertrophic nature of uninephrectomy-induced kidney growth.
The mTORC1 effectors, RPS6 and eIF4E, play distinct roles and are both necessary for AKT/Ras hepatocarcinogenesis.
Activation of mTORC2 (show CRTC2 Antibodies) plays a pivotal role in cardioprotection, and Rps6 is a convergence point of cardioprotective signaling, providing positive feedback regulation of mTORC2 (show CRTC2 Antibodies)/Akt (show AKT1 Antibodies) signaling.
Data indicate that the mTOR (show FRAP1 Antibodies) activity evaluated by the phosphorylation status of ribosomal protein S6, and phospho-S6 (pS6) levels was found declined shortly after rapamycin treatment in both cortex and hippocampus.
regulatory protein (show TGFB1 Antibodies) S6 phosphorylation is controlled by Akt (show AKT1 Antibodies), downstream to PI-3K and upstream to mTOR (show FRAP1 Antibodies) in an IL2 (show IL2 Antibodies)-mediated signal transduction pathway
Rps6 phosphorylation is a determinant of cell size and glucose homeostasis.
the phosphorylation of Tyr (show TYR Antibodies)(1077) on LepRb (show LEPR Antibodies) during receptor activation, substantiate the hypothalamic regulation of STAT5 (show STAT5A Antibodies) and S6 by leptin (show LEP Antibodies), and define the alternate LepRb (show LEPR Antibodies) signaling pathways
rpS6, especially in its unphosphorylated form, is a selective mediator of TRAIL-induced apoptosis
Arg, Leu, and Gln act coordinately to stimulate proliferation of pTr (show PTCHD3 Antibodies) cells through activation of the MTOR (show FRAP1 Antibodies)-RPS6K-RPS6-EIF4EBP1 (show EIF4EBP1 Antibodies) signal transduction pathway.
molecular network including eIF1AX (show EIF1AY Antibodies), RPS7 (show RPS7 Antibodies), and 14-3-3gamma (show YWHAG Antibodies) regulates protein translation and cell proliferation in BMECs.
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
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, ribosomal protein S6
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, phosphoprotein NP33
, ribosomal Protein, Small subunit (28.1 kD) (rps-6)
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