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Ribosomal RNA Processing 8, Methyltransferase, Homolog (Yeast) (RRP8) ELISA Kits

Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. Additionally we are shipping RRP8 Antibodies (21) and RRP8 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human RRP8 RRP8 23378 O43159
Anti-Mouse RRP8 RRP8 101867 Q9DB85
Anti-Rat RRP8 RRP8 308911 Q5U4F0
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More ELISA Kits for RRP8 Interaction Partners

Human Ribosomal RNA Processing 8, Methyltransferase, Homolog (Yeast) (RRP8) interaction partners

  1. Among Systemic lupus erythematosus patients, 63.6% and 45.5% of those with lupus nephritis were positive for anti-RRP8 and anti-TNP1 (show TNP1 ELISA Kits) antibodies, compared with 12.5% and 9.4% of Systemic lupus erythematosus patients without nephritis, respectively.

  2. Data indicate that the the nucleomethylin (NML)-SirT1 (show SIRT1 ELISA Kits) interaction was competitively inhibited by rRNA.

RRP8 Antigen Profile

Antigen Summary

Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys- 9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.

Gene names and symbols associated with RRP8

  • ribosomal RNA processing 8, methyltransferase, homolog (yeast) (RRP8) antibody
  • ribosomal RNA processing 8, methyltransferase, homolog (yeast) (Rrp8) antibody
  • 1500003O22Rik antibody
  • 2900001K19Rik antibody
  • AW538116 antibody
  • KIAA0409 antibody
  • RGD1308302 antibody

Protein level used designations for RRP8

RRP8 methyltransferase homolog , cerebral protein 1 , nucleomethylin , ribosomal RNA-processing protein 8 , cerebral protein 1 homolog

GENE ID SPECIES
23378 Homo sapiens
101867 Mus musculus
308911 Rattus norvegicus
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