anti-Ribosomal RNA Processing 8, Methyltransferase, Homolog (Yeast) (RRP8) Antibodies

Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. Additionally we are shipping RRP8 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RRP8 23378 O43159
RRP8 101867 Q9DB85
RRP8 308911 Q5U4F0
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Top anti-RRP8 Antibodies at antibodies-online.com

Showing 10 out of 21 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: RRP8 Sample Type: Fetal Kidney lysates Antibody Dilution: 1.0ug/ml Rabbit Anti-RRP8 Antibody Catalog Number: ARP68566 Formalin Fixed Paraffin Embedded Tissue: Human Adult Skeletal muscle  Observed Staining: Cytoplasm in hepatocytes Primary Antibody Concentration: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 – 2.0 sec 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: RRP8 Sample Type: Placenta lysates Antibody Dilution: 1.0ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 7 to 9 Days
$478.50
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of RRP8 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated wit Western blot analysis of RRP8 expression in Hela (A), MCF7 (B), Hela (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μL Log in to see 7 to 9 Days
$522.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of KIAA0409 expression in transfected 293T cell line by KIAA0409 MaxPab polyclonal antibody.Lane 1: KIAA0409 transfected lysate(50.16 KDa).Lane 2: Non-transfected lysate. KIAA0409 MaxPab polyclonal antibody. Western Blot analysis of KIAA0409 expression in HeLa. 50 μg Log in to see 11 to 12 Days
$430.00
Details
Human Rabbit Un-conjugated WB   50 μL Log in to see 7 to 9 Days
$463.83
Details
Human Rabbit Un-conjugated IHC (p), WB   50 μg Log in to see 7 to 9 Days
$676.50
Details
Human Mouse Un-conjugated WB   50 μg Log in to see 7 to 9 Days
$742.50
Details

RRP8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,
,

Mouse (Murine) ,


Rat (Rattus)


More Antibodies against RRP8 Interaction Partners

Human Ribosomal RNA Processing 8, Methyltransferase, Homolog (Yeast) (RRP8) interaction partners

  1. NML depletion increases 60S ribosomal protein L11 (RPL11 (show RPL11 Antibodies)) levels in the ribosome-free fraction and protein levels of p53 (show TP53 Antibodies) through an RPL11 (show RPL11 Antibodies)-MDM2 (show MDM2 Antibodies) complex, which activates the p53 (show TP53 Antibodies) pathway.

  2. Among Systemic lupus erythematosus patients, 63.6% and 45.5% of those with lupus nephritis were positive for anti-RRP8 and anti-TNP1 (show TNP1 Antibodies) antibodies, compared with 12.5% and 9.4% of Systemic lupus erythematosus patients without nephritis, respectively.

  3. Data indicate that the the nucleomethylin (NML)-SirT1 (show SIRT1 Antibodies) interaction was competitively inhibited by rRNA.

RRP8 Antigen Profile

Protein Summary

Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys- 9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.

Gene names and symbols associated with RRP8

  • ribosomal RNA processing 8, methyltransferase, homolog (yeast) (RRP8) antibody
  • ribosomal RNA processing 8, methyltransferase, homolog (yeast) (Rrp8) antibody
  • 1500003O22Rik antibody
  • 2900001K19Rik antibody
  • AW538116 antibody
  • KIAA0409 antibody
  • RGD1308302 antibody

Protein level used designations for RRP8

RRP8 methyltransferase homolog , cerebral protein 1 , nucleomethylin , ribosomal RNA-processing protein 8 , cerebral protein 1 homolog

GENE ID SPECIES
23378 Homo sapiens
101867 Mus musculus
308911 Rattus norvegicus
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