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Ring Finger Protein 146 (RNF146) ELISA Kits

E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation. Additionally we are shipping RNF146 Antibodies (26) and RNF146 Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human RNF146 RNF146 81847 Q9NTX7
Anti-Mouse RNF146 RNF146 68031 Q9CZW6
Anti-Rat RNF146 RNF146 308051 Q5XIK5
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More ELISA Kits for RNF146 Interaction Partners

Human Ring Finger Protein 146 (RNF146) interaction partners

  1. the maintenance of unliganded RNF146 in an inactive state may serve to maintain the stability of the RNF146-TNKS (show TNKS ELISA Kits) complex, which in turn regulates the homeostasis of PARylation-dependent ubiquitination activity in the cell

  2. RNF146 regulated the development and progression of NSCLC

  3. Iduna is a Poly(ADP-ribose)-dependent ubiquitin E3 ligase.

  4. RNF146/Iduna has been found to be implicated in neurodegenerative disease and cancer development. [Review]

  5. the RNF146 WWE domain recognizes poly(ADP-ribose) (PAR) by interacting with iso-ADP-ribose (iso-ADPR), the smallest internal PAR structural unit containing the characteristic ribose-ribose glycosidic bond formed during poly(ADP-ribosyl)ation.

  6. RNF146 RING-type ubiquitin E3 ligase as a positive regulator of Wnt (show WNT2 ELISA Kits) signaling that operates with tankyrase to maintain low steady-state levels of Axin (show AXIN1 ELISA Kits) proteins

  7. Dactylidin may function early in the progression of Alzheimer's disease.

  8. Mutations in the coding regions of the RNF146 and ECHDC1 (show ECHDC1 ELISA Kits) genes do not contribute to the burden of inherited predisposition of breast cancer in Ashkenazi high risk women.

Mouse (Murine) Ring Finger Protein 146 (RNF146) interaction partners

  1. Modulation of PARP-1 (show PARP1 ELISA Kits)-mediated oxidative cell injury by ring finger protein 146 (RNF146) in cardiac myocytes

  2. Iduna acts as a potential antioxidant by improving mitochondrial function and inhibiting oxidative stress-induced parthanatos, and these protective effects are dependent on the involvement of ubiquitin-proteasome system.

RNF146 Antigen Profile

Antigen Summary

E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation. Acts as an activator of the Wnt signaling pathway by mediating the ubiquitination of poly-ADP- ribosylated proteins (By similarity).

Gene names and symbols associated with RNF146

  • ring finger protein 146 (RNF146) antibody
  • ring finger protein 146 (Rnf146) antibody
  • ring finger protein 146 (RNF146B) antibody
  • RING finger protein 146 (rn146) antibody
  • ring finger protein 146 (rnf146) antibody
  • 2610509H23Rik antibody
  • dactylidin antibody
  • dJ351K20.1 antibody
  • Iduna antibody
  • rnf146 antibody
  • RP3-351K20.1 antibody
  • wu:fi29e08 antibody
  • zgc:55909 antibody

Protein level used designations for RNF146

2610509H23Rik , E3 ubiquitin-protein ligase RNF146 , dactylidin , iduna , E3 ubiquitin-protein ligase RNF146-B , RING finger protein 146-B , E3 ubiquitin-protein ligase rnf146

GENE ID SPECIES
100067400 Equus caballus
81847 Homo sapiens
68031 Mus musculus
308051 Rattus norvegicus
425313 Gallus gallus
476288 Canis lupus familiaris
100512692 Sus scrofa
767901 Bos taurus
100380617 Salmo salar
443895 Xenopus laevis
334065 Danio rerio
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