anti-Ring Finger Protein 169 (RNF169) Antibodies

Probable E3 ubiquitin-protein ligase that acts as a negative regulator of double-strand breaks (DSBs) repair following DNA damage. Additionally we are shipping RNF169 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RNF169 254225 Q8NCN4
RNF169 108937 E9Q7F2
RNF169 685009  
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Top anti-RNF169 Antibodies at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-RNF169 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB RNF169 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 2 to 3 Days
$473.93
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Paraformaldehyde-fixed, paraffin embedded Mouse heart tissue, Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes, Blocking buffer (normal goat serum) at 37°C for 30min, Antibody incubation with RNF169 Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, followed by a conjugated secondary and DAB staining Paraformaldehyde-fixed, paraffin embedded Mouse heart tissue, Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes, Blocking buffer (normal goat serum) at 37°C for 30min, Antibody incubation with RNF169 Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, followed by a conjugated secondary and DAPI staining 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

RNF169 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against RNF169 Interaction Partners

Human Ring Finger Protein 169 (RNF169) interaction partners

  1. Ubiquitin ligases RNF168 (show RNF168 Antibodies), RNF169, and RAD18 (show RAD18 Antibodies) specifically bind histone H2A Lys13/15-ubiquitylated nucleosomes. 53BP1 (show TP53BP1 Antibodies) chromatin recruitment may be activated by RNF168 (show RNF168 Antibodies) and blocked by RNF169 and RAD18 (show RAD18 Antibodies).

  2. RNF169 as a component in DNA damage signal transduction and adds to the complexity of regulatory ubiquitylation in genome stability maintenance.

  3. RNF168, its paralog RNF169, RAD18, and the BRCA1-interacting RAP80 protein accumulate at DNA double strand break sites through the use of bipartite modules composed of ubiquitin binding domains.

  4. results show that RNF169 functions in a noncanonical fashion to harness RNF168 (show RNF168 Antibodies)-mediated protein recruitment to DSB-containing chromatin, thereby contributing to regulation of DSB repair pathway utilization.

RNF169 Antigen Profile

Protein Summary

Probable E3 ubiquitin-protein ligase that acts as a negative regulator of double-strand breaks (DSBs) repair following DNA damage. Recruited to DSB repair sites by recognizing and binding ubiquitin catalyzed by RNF168 and competes with TP53BP1 and BRCA1 for association with RNF168-modified chromatin, thereby acting as a negative regulator of DSBs repair. E3 ubiquitin- protein ligase activity is not required for regulation of DSBs repair (By similarity).

Gene names and symbols associated with RNF169

  • ring finger protein 169 (RNF169) antibody
  • ring finger protein 169 (Rnf169) antibody
  • 2900057K09Rik antibody

Protein level used designations for RNF169

E3 ubiquitin-protein ligase RNF169

GENE ID SPECIES
419055 Gallus gallus
100739168 Sus scrofa
525756 Bos taurus
254225 Homo sapiens
609300 Canis lupus familiaris
108937 Mus musculus
685009 Rattus norvegicus
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