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anti-Ring Finger Protein 4 (RNF4) Antibodies

The protein encoded by RNF4 contains a RING finger motif and acts as a transcription regulator. Additionally we are shipping RNF4 Kits (29) and RNF4 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RNF4 6047 P78317
RNF4 19822 Q9QZS2
Anti-Rat RNF4 RNF4 29274 O88846
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Top anti-RNF4 Antibodies at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis in LNCaP cell line lysates (35ug/lane) using RNF4 Antibody (C-term) Cat.-No AP53693PU-N. This demonstrates the RNF4 antibody detected the RNF4 protein (arrow). Western blot analysis in T47D cell line lysates (35µg/lane) using RNF4 Antibody (C-term) Cat.-No AP53693PU-N. This demonstrates the RNF4 antibody detected the RNF4 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB RNF4 Antibody (C-term)  western blot analysis in LNCaP cell line lysates (35ug/lane).This demonstrates the RNF4 antibody detected the RNF4 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) 200 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (35.35 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 11 to 16 Days
$531.14
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit FITC ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details

RNF4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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, , , , ,
Mouse (Murine)


Top referenced anti-RNF4 Antibodies

  1. Human Polyclonal RNF4 Primary Antibody for EIA, WB - ABIN954575 : Hu, Rodrigues, Tao, Baker, Miraglia, Orth, Lyons, Schultz, Wu: Identification of RING finger protein 4 (RNF4) as a modulator of DNA demethylation through a functional genomics screen. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Show all 4 references for ABIN954575

  2. Human Polyclonal RNF4 Primary Antibody for WB - ABIN1537658 : Wang, Sang, Ren, Liu, Liu, Zhang, Wang, Wang, Orian, Yang, Yi: SENP3 regulates the global protein turnover and the Sp1 level via antagonizing SUMO2/3-targeted ubiquitination and degradation. in Protein & cell 2015 (PubMed)

More Antibodies against RNF4 Interaction Partners

Human Ring Finger Protein 4 (RNF4) interaction partners

  1. c-Myc (show MYC Antibodies) is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1 (show PIAS1 Antibodies), SENP7 (show SENP7 Antibodies) and RNF4

  2. Data show that RNF4 is a SUMO-targeted ubiquitin ligase that targets TRF2 (show TERF2 Antibodies) for ubiquitination.

  3. novel insight into cross-talk between ubiquitin and SUMO and uncover USP11 (show USP11 Antibodies) and RNF4 as a balanced SUMO-targeted ubiquitin ligase/protease pair with a role in the DDR (show DDR1 Antibodies).

  4. RNF4 negatively regulates NF-kappaB (show NFKB1 Antibodies) signaling by down-regulating TAB2 (show TAB2 Antibodies)

  5. RNF4 enhances Ube2E1 (show UBE2E1 Antibodies) self-ubiquitination.

  6. NMR spectroscopy and biochemical characterization reveal how RNF4 manipulates the conformation of the SUMO chain, thereby facilitating optimal delivery of the distal SUMO domain for ubiquitin transfer.

  7. RecQ-like helicase BLM subcellular localization is regulated by SUMO-targeted ubiquitin ligase RNF4 in response to DNA damage, presumably to prevent illegitimate recombination events.

  8. Cells lacking RNF4 exhibited interstrand cross-linker hypersensitivity. The gene encoding RNF4 was epistatic with the other genes encoding members of the FA/BRCA pathway.

  9. RNF4 mediates ubiquitination and turnover of MeCP2 (show MECP2 Antibodies) and thus derepresses transcription from DNA methylation (show HELLS Antibodies).

  10. the ARM dynamically regulates the SIM (show SIM2 Antibodies)-dependent recruitment of targets to RNF4, which could be critical to dynamically fine-tune the abundance of Ser (show SIGLEC1 Antibodies)(P)-824-SUMO-KAP1 (show CDKN3 Antibodies) and, potentially, other SUMOylated proteins during DNA damage response.

Mouse (Murine) Ring Finger Protein 4 (RNF4) interaction partners

  1. This paper identifies a nucleosome-targeting motif within the RNF4 RING domain that can bind DNA and thereby enables RNF4 to selectively ubiquitinate nucleosomal histones.

  2. fork collapse in Atr (show ATR Antibodies)-deleted cells is mediated through the combined effects the sumo targeted E3-ubiquitin ligase RNF4 and activation of the AURKA (show AURKA Antibodies)-PLK1 (show PLK1 Antibodies) pathway

  3. Rnf4 controls protein localization at DNA damage sites by integrating SUMOylation and ubiquitylation events.

  4. SUMO interacting motif is dispensable for PML (show PML Antibodies) SUMOylation and interaction with RNF4 but is required for efficient PML (show PML Antibodies) ubiquitination, recruitment of proteasome components within NBs (show NLRP2 Antibodies) and proteasome-dependent degradation of PML (show PML Antibodies) in response to AsO

  5. Rnf4 deficiency is embryonic lethal with higher levels of methylation in genomic DNA. Mechanistic studies show that RNF4 interacts with and requires the base excision repair enzymes TDG (show TDG Antibodies) and APE1 (show APEX1 Antibodies) for active demethylation.

  6. GC-rich (show RELB Antibodies) elements flanking the transcription start site govern activation

  7. 1.6- and 3.0-kb transcripts originate from the same promoter, encode for the same protein and differ in the 3' UTR (show UTS2R Antibodies).

  8. RNF4 is a negative regulator of TRPS1 (show TRPS1 Antibodies) activity

  9. results suggest a role for small nuclear ring finger protein(SNURF/RNF4) in fetal germ cell development as well as in oocyte and granulosa cell maturation in an estrogen- and gonadotropin-regulated fashion

  10. Rnf4 possesses ubiquitin E3 ligase activity.

RNF4 Antigen Profile

Protein Summary

The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.

Gene names and symbols associated with RNF4

  • ring finger protein 4 (RNF4) antibody
  • ring finger protein 4 (Rnf4) antibody
  • ring finger protein 4 (LOC100348357) antibody
  • AU018689 antibody
  • Gtrgeo8 antibody
  • SLX5 antibody
  • SNURF antibody

Protein level used designations for RNF4

E3 ubiquitin ligase RNF4 , E3 ubiquitin-protein ligase RNF4 , small nuclear RING finger protein , gene trap ROSA b-geo 8 , SNURF , small nuclear ring finger protein , RING finger protein 4

GENE ID SPECIES
6047 Homo sapiens
19822 Mus musculus
29274 Rattus norvegicus
100348357 Oryctolagus cuniculus
100735750 Cavia porcellus
692189 Sus scrofa
617018 Bos taurus
101110510 Ovis aries
610552 Canis lupus familiaris
422886 Gallus gallus
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