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The protein encoded by RNF40 contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. Additionally we are shipping RNF40 Proteins (3) and many more products for this protein.
Showing 10 out of 48 products:
Cow (Bovine) Polyclonal RNF40 Primary Antibody for IHC, WB - ABIN2774720
Zhu, Zheng, Pham, Mandal, Erdjument-Bromage, Tempst, Reinberg: Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation. in Molecular cell 2005
We show that Bre1 (show RNF20 Antibodies) (human BRE1A (show RNF20 Antibodies)/B (RNF20 (show RNF20 Antibodies)/40) and mouse Bre1a (show RNF20 Antibodies)/b (Rnf20 (show RNF20 Antibodies)/40)) acts as an important suppressor of chromosomal instability
the observed defects in the radiation response of Bre1a (show RNF20 Antibodies)/b-deficient cells
our results suggest that RNF20 and RNF40, either via ubiquitylation of H2B or other targets, are coupled to the proliferation of prostate cancer cells.
RNF40 cooperates with SUPT16H (show SUPT16H Antibodies) to induce dynamic changes in chromatin structure during DNA double-strand break repair.
Studies indicate that H2B monoubiquitylation is driven primarily by an E3 ubiquitin ligase (show MUL1 Antibodies) composed of the two RING finger (show PCGF1 Antibodies) proteins RNF20 (show RNF20 Antibodies) and RNF40.
Formation of trimeric complex UbcH6 and RNF20/40 with PAF stimulates histone 2B monoubiquitination activity in vitro
The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, E3 ubiquitin-protein ligase BRE1B
, 95 kDa retinoblastoma protein binding protein
, 95 kDa retinoblastoma-associated protein
, BRE1 E3 ubiquitin ligase homolog B
, Rb-associated protein
, protein staring
, staring protein
, syntaxin-1-interacting RING finger protein