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RNF41 encodes an E3 ubiquitin ligase. Additionally we are shipping RNF41 Proteins (9) and many more products for this protein.
Showing 10 out of 42 products:
Cow (Bovine) Polyclonal RNF41 Primary Antibody for WB - ABIN2775956
Cao, Wu, Yen, Sweeney, Carraway: Neuregulin-induced ErbB3 downregulation is mediated by a protein stability cascade involving the E3 ubiquitin ligase Nrdp1. in Molecular and cellular biology 2007
HPV 16 E2 can modulate ErbB-3 (show ERBB3 Antibodies) by interacting with Nrdp-1, which is involved in the regulation of this receptor, via ubiquitination and degradation.
The results of this study suggested that Nrdp1-mediated ErbB3 (show ERBB3 Antibodies) degradation suppresses glioma migration and invasion and that loss of Nrdp1 may amplify ErbB3 (show ERBB3 Antibodies) signaling to contribute to glioma migration and invasion.
ABPN downregulates multiple components of the EGFR (show EGFR Antibodies)/ErbB3 (show ERBB3 Antibodies) signaling pathway through Nrdp1 activation.
Nrdp1 may serve as a useful biomarker for the clinical outcome and efficacy of adjuvant anthracyclines-based chemotherapy in breast cancer.
The regulation of MMP7 (show MMP7 Antibodies) by Nrdp1 in CRC (show CALR Antibodies) cells could be inhibited by miR (show MLXIP Antibodies)-497 through suppressing Nrdp1 translation.
Lower expression of Nrdp1 in human glioma contributes tumor progression by reducing apoptosis.
Our findings thus reveal Nrdp1, EGFR (show EGFR Antibodies) signaling, and MMP7 (show MMP7 Antibodies) as promising therapeutic targets for preventing the metastasis of colorectal cancer .
Data suggest that neuregulin receptor degradation protein-1 (Nrtp1) may induce cell-cycle inhibitor (show CDKN2A Antibodies) p27 (show PAK2 Antibodies) nuclear retention to directly inhibit proliferation of colorectal cancer (CRC (show CALR Antibodies)) cells.
Phosphorylation of RNF41 by Par-1b (show MARK2 Antibodies) regulates basolateral membrane targeting of laminin-111 receptors.
Balanced reciprocal cross-regulation of RNF41 and USP8 (show USP8 Antibodies) determines whether receptors are sorted for lysosomal degradation or recycling, this way regulating basal cytokine receptor (show EBI3 Antibodies) levels.
Data suggest that ring finger protein 41 Nrdp1 terminates T cell antigen receptors (TCRs) signaling by inactivating Zap70 (show ZAP70 Antibodies) kinase.
The novel Pdx1 (show PDX1 Antibodies)-Clec16a (show CLEC16A Antibodies)-Nrdp1 pathway this study describes provides a genetic basis for the pathogenesis of mitochondrial dysfunction in multiple forms of diabetes.
demonstrate that Nrdp1-mediated ubiquitination and activation of C/EBPbeta (show CEBPB Antibodies) contributes to a ubiquitin-dependent nonproteolytic pathway that up-regulates Arg1 (show ARG1 Antibodies) expression and promotes M2 macrophage polarization
Nrdp1 may be a key mediator in the development of cardiac dysfunction after DOX treatment and associated with inhibition of Akt (show AKT1 Antibodies), ERK1/2 (show MAPK1/3 Antibodies) and STAT3 (show STAT3 Antibodies).
these results provide evidence for an important role for Nrdp1 in regulating ischemia/reperfusioninduced cardiac injury
Post-transcriptional mechanisms contribute to the suppression of the ErbB3 (show ERBB3 Antibodies) negative regulator protein Nrdp1 in mammary tumors.
Rnf41 is nominated as a candidate gene for anxiety-like behaviors, depression, and vulnerability to seizures.
Data suggest that Nrdp1 functions as both an adaptor protein and an E3 unbiquitin ligase to regulate TLR responses in different ways.
gene generates two isoforms differing in their expression patterns and in regulatory functions (Nrdp1 or neuregulin receptor degradation protein-1)
Nrdp1 is associated with differentiation process of the melanocyte lineage by regulating Erbb3b, an Erbb (show EGFR Antibodies) signaling molecule along zebrafish embryogenesis.
This gene encodes an E3 ubiquitin ligase. The encoded protein plays a role in type 1 cytokine receptor signaling by controlling the balance between JAK2-associated cytokine receptor degradation and ectodomain shedding. Alternative splicing results in multiple transcript variants.
E3 ubiquitin-protein ligase NRDP1
, fetal liver ring finger
, neuregulin receptor degradation protein-1