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RNF41 encodes an E3 ubiquitin ligase. Additionally we are shipping RNF41 Antibodies (42) and RNF41 Proteins (9) and many more products for this protein.
HPV 16 E2 can modulate ErbB-3 (show ERBB3 ELISA Kits) by interacting with Nrdp-1, which is involved in the regulation of this receptor, via ubiquitination and degradation.
The results of this study suggested that Nrdp1-mediated ErbB3 (show ERBB3 ELISA Kits) degradation suppresses glioma migration and invasion and that loss of Nrdp1 may amplify ErbB3 (show ERBB3 ELISA Kits) signaling to contribute to glioma migration and invasion.
ABPN downregulates multiple components of the EGFR (show EGFR ELISA Kits)/ErbB3 (show ERBB3 ELISA Kits) signaling pathway through Nrdp1 activation.
Nrdp1 may serve as a useful biomarker for the clinical outcome and efficacy of adjuvant anthracyclines-based chemotherapy in breast cancer.
The regulation of MMP7 (show MMP7 ELISA Kits) by Nrdp1 in CRC (show CALR ELISA Kits) cells could be inhibited by miR (show MLXIP ELISA Kits)-497 through suppressing Nrdp1 translation.
Lower expression of Nrdp1 in human glioma contributes tumor progression by reducing apoptosis.
Our findings thus reveal Nrdp1, EGFR (show EGFR ELISA Kits) signaling, and MMP7 (show MMP7 ELISA Kits) as promising therapeutic targets for preventing the metastasis of colorectal cancer .
Data suggest that neuregulin receptor degradation protein-1 (Nrtp1) may induce cell-cycle inhibitor p27 (show PAK2 ELISA Kits) nuclear retention to directly inhibit proliferation of colorectal cancer (CRC (show CALR ELISA Kits)) cells.
Phosphorylation of RNF41 by Par-1b (show MARK2 ELISA Kits) regulates basolateral membrane targeting of laminin-111 receptors.
Balanced reciprocal cross-regulation of RNF41 and USP8 (show USP8 ELISA Kits) determines whether receptors are sorted for lysosomal degradation or recycling, this way regulating basal cytokine receptor (show EBI3 ELISA Kits) levels.
Data suggest that ring finger protein 41 Nrdp1 terminates T cell antigen receptors (TCRs) signaling by inactivating Zap70 (show ZAP70 ELISA Kits) kinase.
The novel Pdx1 (show PDX1 ELISA Kits)-Clec16a (show CLEC16A ELISA Kits)-Nrdp1 pathway this study describes provides a genetic basis for the pathogenesis of mitochondrial dysfunction in multiple forms of diabetes.
demonstrate that Nrdp1-mediated ubiquitination and activation of C/EBPbeta (show CEBPB ELISA Kits) contributes to a ubiquitin-dependent nonproteolytic pathway that up-regulates Arg1 (show ARG1 ELISA Kits) expression and promotes M2 macrophage polarization
Nrdp1 may be a key mediator in the development of cardiac dysfunction after DOX treatment and associated with inhibition of Akt (show AKT1 ELISA Kits), ERK1/2 (show MAPK1/3 ELISA Kits) and STAT3 (show STAT3 ELISA Kits).
these results provide evidence for an important role for Nrdp1 in regulating ischemia/reperfusioninduced cardiac injury
Post-transcriptional mechanisms contribute to the suppression of the ErbB3 (show ERBB3 ELISA Kits) negative regulator protein Nrdp1 in mammary tumors.
Rnf41 is nominated as a candidate gene for anxiety-like behaviors, depression, and vulnerability to seizures.
Data suggest that Nrdp1 functions as both an adaptor protein and an E3 unbiquitin ligase to regulate TLR responses in different ways.
gene generates two isoforms differing in their expression patterns and in regulatory functions (Nrdp1 or neuregulin receptor degradation protein-1)
Nrdp1 is associated with differentiation process of the melanocyte lineage by regulating Erbb3b, an Erbb (show EGFR ELISA Kits) signaling molecule along zebrafish embryogenesis.
This gene encodes an E3 ubiquitin ligase. The encoded protein plays a role in type 1 cytokine receptor signaling by controlling the balance between JAK2-associated cytokine receptor degradation and ectodomain shedding. Alternative splicing results in multiple transcript variants.
E3 ubiquitin-protein ligase NRDP1
, fetal liver ring finger
, neuregulin receptor degradation protein-1