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RNF41 encodes an E3 ubiquitin ligase. Additionally we are shipping RNF41 Antibodies (43) and many more products for this protein.
Showing 8 out of 9 products:
HPV 16 E2 can modulate ErbB-3 (show ERBB3 Proteins) by interacting with Nrdp-1, which is involved in the regulation of this receptor, via ubiquitination and degradation.
The results of this study suggested that Nrdp1-mediated ErbB3 (show ERBB3 Proteins) degradation suppresses glioma migration and invasion and that loss of Nrdp1 may amplify ErbB3 (show ERBB3 Proteins) signaling to contribute to glioma migration and invasion.
ABPN downregulates multiple components of the EGFR (show EGFR Proteins)/ErbB3 (show ERBB3 Proteins) signaling pathway through Nrdp1 activation.
Nrdp1 may serve as a useful biomarker for the clinical outcome and efficacy of adjuvant anthracyclines-based chemotherapy in breast cancer.
The regulation of MMP7 (show MMP7 Proteins) by Nrdp1 in CRC (show CALR Proteins) cells could be inhibited by miR (show MLXIP Proteins)-497 through suppressing Nrdp1 translation.
Lower expression of Nrdp1 in human glioma contributes tumor progression by reducing apoptosis.
Our findings thus reveal Nrdp1, EGFR (show EGFR Proteins) signaling, and MMP7 (show MMP7 Proteins) as promising therapeutic targets for preventing the metastasis of colorectal cancer .
Data suggest that neuregulin receptor degradation protein-1 (Nrtp1) may induce cell-cycle inhibitor p27 (show PAK2 Proteins) nuclear retention to directly inhibit proliferation of colorectal cancer (CRC (show CALR Proteins)) cells.
Phosphorylation of RNF41 by Par-1b (show MARK2 Proteins) regulates basolateral membrane targeting of laminin-111 receptors.
Balanced reciprocal cross-regulation of RNF41 and USP8 (show USP8 Proteins) determines whether receptors are sorted for lysosomal degradation or recycling, this way regulating basal cytokine receptor (show EBI3 Proteins) levels.
Data suggest that ring finger protein 41 Nrdp1 terminates T cell antigen receptors (TCRs) signaling by inactivating Zap70 (show ZAP70 Proteins) kinase.
The novel Pdx1 (show PDX1 Proteins)-Clec16a-Nrdp1 pathway this study describes provides a genetic basis for the pathogenesis of mitochondrial dysfunction in multiple forms of diabetes.
demonstrate that Nrdp1-mediated ubiquitination and activation of C/EBPbeta (show CEBPB Proteins) contributes to a ubiquitin-dependent nonproteolytic pathway that up-regulates Arg1 (show ARG1 Proteins) expression and promotes M2 macrophage polarization
Nrdp1 may be a key mediator in the development of cardiac dysfunction after DOX treatment and associated with inhibition of Akt (show AKT1 Proteins), ERK1/2 and STAT3 (show STAT3 Proteins).
these results provide evidence for an important role for Nrdp1 in regulating ischemia/reperfusioninduced cardiac injury
Post-transcriptional mechanisms contribute to the suppression of the ErbB3 (show ERBB3 Proteins) negative regulator protein Nrdp1 in mammary tumors.
Rnf41 is nominated as a candidate gene for anxiety-like behaviors, depression, and vulnerability to seizures.
Data suggest that Nrdp1 functions as both an adaptor protein and an E3 unbiquitin ligase to regulate TLR responses in different ways.
Nrdp1 is associated with differentiation process of the melanocyte lineage by regulating Erbb3b, an Erbb (show EGFR Proteins) signaling molecule along zebrafish embryogenesis.
This gene encodes an E3 ubiquitin ligase. The encoded protein plays a role in type 1 cytokine receptor signaling by controlling the balance between JAK2-associated cytokine receptor degradation and ectodomain shedding. Alternative splicing results in multiple transcript variants.
E3 ubiquitin-protein ligase NRDP1
, fetal liver ring finger
, neuregulin receptor degradation protein-1